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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:49 PM EDT

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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hernia Incisional Clear all
Completed No phase listed Observational Accepts healthy volunteers Results available

Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement

NCT01325792
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
GORE® BIO-A® Tissue Reinforcement
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
8
States / cities
San Diego, California • Indianapolis, Indiana • St Louis, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2015 · Synced Oct 23, 2026, 1:49 PM EDT
Completed Not applicable Interventional Results available

Repair of Infected or Contaminated Hernias

NCT00617357
View directory record Official record
Conditions
Hernia
Interventions
LTM (Strattice Reconstructive Tissue Matrix)
Device
Lead sponsor
LifeCell
Industry
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
15
States / cities
La Jolla, California • New Haven, Connecticut • New Orleans, Louisiana + 10 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Oct 23, 2026, 1:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh

NCT06409091
View directory record Official record
Conditions
Hernia, Ventral, Hernia Incisional
Interventions
Medium weight or Heavy weight mesh
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,496 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 23, 2026, 1:49 PM EDT
Withdrawn Phase 3 Interventional

Peri-Incisional Drug Injection in Lumbar Spine Surgery

NCT03513445
View directory record Official record
Conditions
Lumbar Disc Herniation, Degenerative Disc Disease, Spondylolisthesis
Interventions
Morphine, Epinephrine, naropin
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2022 · Synced Oct 23, 2026, 1:49 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?

NCT02007096
View directory record Official record
Conditions
Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications, Pain, Postoperative
Interventions
Transabdominal Plane Block, Non Transabdominal Plane Block
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 19, 2018 · Synced Oct 23, 2026, 1:49 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cytokine Response to Abdominal Wall Reconstruction

NCT07422584
View directory record Official record
Conditions
Incisional Ventral Hernia
Interventions
Not applicable- observational study
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 23, 2026, 1:49 PM EDT
Not listed No phase listed Observational Results available

Review of Complex Recurrent Hernia Repair

NCT01644695
View directory record Official record
Conditions
Recurrent Hernia
Interventions
Bony Anchoring Reinforcement System
Procedure
Lead sponsor
Institute For Advanced Reconstruction
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Shrewsbury, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 15, 2012 · Synced Oct 23, 2026, 1:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Suture Repair vs Mesh Repair for Incisional Hernia

NCT05599750
View directory record Official record
Conditions
Incisional Hernia
Interventions
Incisional hernia repair
Procedure
Lead sponsor
Clayton Petro
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2031
U.S. locations
5
States / cities
Gainesville, Florida • Chicago, Illinois • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 23, 2026, 1:49 PM EDT
Completed No phase listed Observational Results available

A Prospective, Observational Study Utilizing Phasix™ Mesh During Ventral and Incisional Hernia Repair Surgery

NCT01863030
View directory record Official record
Conditions
Ventral Hernia
Interventions
Phasix mesh implant
Device
Lead sponsor
John Roth
Other
Eligibility
18 Years to 100 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 23, 2026, 1:49 PM EDT
Completed No phase listed Observational

Observational Study to Evaluate Ventral Incisional Hernia Repair Using a Biologic Mesh (Cook Biodesign)

NCT02129140
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Hernia graft/mesh
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 23, 2026, 1:49 PM EDT
Terminated No phase listed Observational

Observational Biologic or Prosthetic Mesh

NCT03317665
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Mesh for hernia repair
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Oct 23, 2026, 1:49 PM EDT
Active, not recruiting Not applicable Interventional

Effect of Duramesh™ on Hernia Formation After Ileostomy Closure

NCT06511414
View directory record Official record
Conditions
Incisional Hernia, Ileostomy - Stoma
Interventions
duramesh, Control
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 23, 2026, 1:49 PM EDT
Recruiting Not applicable Interventional

Use of Stratafix Symmetric™ to Prevent Incisional Hernia in Gastrointestinal and Abdominal Surgery

NCT06063577
View directory record Official record
Conditions
C.Surgical Procedure; Disruption of Wound, Suture
Interventions
Stratafix suture, Standard of care suture
Device
Lead sponsor
West Michigan Cancer Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 23, 2026, 1:49 PM EDT
Withdrawn Not applicable Interventional

DuraMesh Laparotomy Closure Following Trauma and Emergency Surgery

NCT04312165
View directory record Official record
Conditions
Hernia Incisional, Suture, Complication
Interventions
Duramesh Laparotomy Closure, Conventional suture closure
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 23, 2026, 1:49 PM EDT
Completed Not applicable Interventional

Watchful Waiting of Incisional Hernias

NCT00351455
View directory record Official record
Conditions
Incisional Hernia, Ventral Hernia, Umbilical Hernia
Interventions
smoking cessation, tighter diabetic control, diet and exercise program
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 23, 2026, 1:49 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparative Study of Biologic Mesh Versus Repair With Component Separation.

NCT01295125
View directory record Official record
Conditions
Ventral Hernia
Interventions
XenMATRIX mesh, Open abdominal ventral hernia repair
Device · Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 23, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ultrasound Assessment of Ventral Hernia Defects

NCT03043079
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Ultrasound Acoustic Radiation Forced Impulse Shear Wave Velocity
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
20 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 23, 2026, 1:49 PM EDT
Completed Not applicable Interventional

Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation

NCT03938688
View directory record Official record
Conditions
Ventral Hernia, Incisional Hernia
Interventions
Mesh placement with Transfascial Sutures
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 23, 2026, 1:49 PM EDT
Recruiting Phase 4 Interventional

Preoperative BOTOX® Injection for Large Ventral Hernia Repair

NCT07220382
View directory record Official record
Conditions
Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome, Hernia Surgery, Hernia, Hernia Incisional
Interventions
OnabotulinumtoxinA Injection, Saline (placebo) Injection, OnabotulinumtoxinA, 0.9 % Normal Saline, Open Ventral Hernia Repair
Procedure · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 23, 2026, 1:49 PM EDT
Completed Not applicable Interventional Results available

A Prospective, Multicenter All Comers Study of Phasix Mesh for Ventral or Incisional Hernia Repair

NCT02053168
View directory record Official record
Conditions
Ventral Hernia, Incisional Hernia
Interventions
Resorbable Mesh
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
6
States / cities
Beverly Hills, California • Los Angeles, California • Celebration, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 23, 2026, 1:49 PM EDT
Not yet recruiting Not applicable Interventional

Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia Repair

NCT07874724
View directory record Official record
Conditions
Ventral Hernia, Incisional Hernia, Hernia, Hernia Abdominal Wall, Hernia Incisional, Hernia Incisional Ventral, Hernia of Abdominal Wall, Hernia Surgery
Interventions
Cryoneurolysis
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 23, 2026, 1:49 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

A Prospective, Double-Blinded, Randomized Controlled Trial of dHACM for Incisional Hernia Prophylaxis

NCT04417140
View directory record Official record
Conditions
Incisional Hernia
Interventions
dHACM (AmnioWrap)
Biological
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
533 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 23, 2026, 1:49 PM EDT
Not yet recruiting Not applicable Interventional

The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

NCT07145099
View directory record Official record
Conditions
Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
Interventions
PT Group, Usual Care
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 23, 2026, 1:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Tension in Posterior Component Separation for Abdominal Wall Reconstruction

NCT05142761
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Not listed
Lead sponsor
Michael Rosen
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 23, 2026, 1:49 PM EDT