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ClinicalTrials.gov public records Last synced Sep 26, 2026, 2:27 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Herniorrhaphy Clear all
Active, not recruiting No phase listed Observational

Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application

NCT05094089
View directory record Official record
Conditions
Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
Interventions
Hernia repair with mesh
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years to 80 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Grand Rapids, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional

Music Therapy in the Treatment of Perioperative Anxiety and Pain

NCT05263635
View directory record Official record
Conditions
Pain, Post Operative, Anxiety, Opioid Use
Interventions
Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS)
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Sep 26, 2026, 2:27 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Impact of Quadratus Lumborum Block on Recovery Profile After Ventral Hernia Repair

NCT03794882
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use
Interventions
Quadratus Lumborum Block, Standard Medical Management
Combination Product · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Phase 3 Interventional

Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Herniorrhaphy

NCT06215859
View directory record Official record
Conditions
Acute Pain, Post Operative Pain, Pain
Interventions
MR-107A-02, Tramadol, Placebo, Herniorrhaphy
Drug · Procedure
Lead sponsor
Viatris Specialty LLC
Industry
Eligibility
18 Years and older
Enrollment
579 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
18
States / cities
Sheffield, Alabama • Phoenix, Arizona • Anaheim, California + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional Results available

Continuous Local Anesthetic Infusion Following Hernia Repair

NCT01804114
View directory record Official record
Conditions
Ventral Hernia
Interventions
Pain management following hernia repair, Placebo for pain management following hernia repair
Procedure
Lead sponsor
Endeavor Health
Other
Eligibility
19 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Phase 3 Interventional

An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries

NCT04785638
View directory record Official record
Conditions
Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy, Colectomy, Reduction Mammoplasty
Interventions
INL-001 (bupivacaine hydrochloride) implant
Combination Product
Lead sponsor
Innocoll
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
8
States / cities
Florence, Alabama • Sheffield, Alabama • Pasadena, California + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional

Hernia Repair With or Without Sutures

NCT00905320
View directory record Official record
Conditions
Hernia
Interventions
Metallic Fasteners and Sutures, Metallic Fasteners Alone
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Sep 26, 2026, 2:27 AM EDT
Not listed Not applicable Interventional

Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial

NCT02363790
View directory record Official record
Conditions
Hernia, Ventral
Interventions
LVHR PFC, Bridging LVHR
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Iowa City, Iowa • Lexington, Kentucky + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2018 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Phase 3 Interventional

Does Tension-Free Herniorrhaphy or Laparoscopic Herniorrhaphy Achieve Equal or Better Recurrence Rates and Lower Costs While Achieving Equivalent Outcomes for Hernia Patients?

NCT00032448
View directory record Official record
Conditions
Hernia
Interventions
Standardized tension-free herniorrhaphy with prosthesis
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Male only
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
14
States / cities
Birmingham, Alabama • No. Little Rock, Arkansas • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2011 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional Results available

Miromatrix Biological Mesh for Hiatal Hernia Repair

NCT02436681
View directory record Official record
Conditions
Hiatal Hernia
Interventions
MIROMESH
Device
Lead sponsor
Miromatrix Medical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
6
States / cities
Lexington, Kentucky • Long Branch, New Jersey • Charlotte, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Sep 26, 2026, 2:27 AM EDT
Terminated Not applicable Interventional Results available

The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients

NCT01794338
View directory record Official record
Conditions
Ventral Hernia
Interventions
Strattice Arm, Bio-A Arm
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2022 · Synced Sep 26, 2026, 2:27 AM EDT
Completed No phase listed Observational

Analysis and Characterization of Biologic Implants

NCT01060046
View directory record Official record
Conditions
Ventral Hernia, Post-mastectomy Breast Reconstruction
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 13, 2018 · Synced Sep 26, 2026, 2:27 AM EDT
Enrolling by invitation Not applicable Interventional

Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair

NCT06874413
View directory record Official record
Conditions
Frailty, Ventral Hernia
Interventions
Prehabilitation, Standard of Care (SOC)
Behavioral · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
65 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Transabdominal Plane (TAP) Blocks for Inguinal Hernia Repairs

NCT05672680
View directory record Official record
Conditions
Inguinal Hernia
Interventions
0.25% Bupivacaine, Placebo, TAP block
Drug · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Sep 26, 2026, 2:27 AM EDT
Completed No phase listed Observational Results available

Study Of Hernia Repair Utilizing The Bard Ventrio Hernia Patch

NCT00866814
View directory record Official record
Conditions
Ventral Hernia
Interventions
Bard Ventrio Hernia Patch
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
7
States / cities
Sacramento, California • Pensacola, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Phase 4 Interventional Results available

Does Preop Midazolam Maintain Blood Glucose Norms in the Non Diabetic Perioperative Period

NCT01641653
View directory record Official record
Conditions
Hernia
Interventions
Normal saline, Midazolam
Other · Drug
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Sep 26, 2026, 2:27 AM EDT
Completed No phase listed Observational

Flexible Composite Next Generation Tissue Separating Mesh in Laparoscopic Incisional/Ventral Hernia Repair

NCT01162564
View directory record Official record
Conditions
Incisional Hernia, Ventral Hernia
Interventions
NG-TSM
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
6
States / cities
Jefferson City, Missouri • St Louis, Missouri • The Bronx, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2011 · Synced Sep 26, 2026, 2:27 AM EDT
Completed No phase listed Observational Results available

A Prospective, Observational Study Utilizing Phasix™ Mesh During Ventral and Incisional Hernia Repair Surgery

NCT01863030
View directory record Official record
Conditions
Ventral Hernia
Interventions
Phasix mesh implant
Device
Lead sponsor
John Roth
Other
Eligibility
18 Years to 100 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 20, 2020 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional

Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery

NCT05374096
View directory record Official record
Conditions
Postoperative Pain, Acute, Ventral Hernia, Hernia Abdominal Wall, Surgery, Anxiety
Interventions
Patient-Chosen Music, Placebo
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Sep 26, 2026, 2:27 AM EDT
Completed No phase listed Observational Results available

Complications, Outcomes and Revisions Following Hiatal Hernia Repair With MIROMESH

NCT03735862
View directory record Official record
Conditions
Hiatal Hernia With Gastroesophageal Reflux Disease, Gastroesophageal Reflux, GERD
Interventions
Hepatic derived surgical matrix
Biological
Lead sponsor
Miromatrix Medical Inc.
Industry
Eligibility
Not listed
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lorton, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Sep 26, 2026, 2:27 AM EDT
Terminated Not applicable Interventional

Gentrix™ Versus Biological or Prosthetic Mesh

NCT03034213
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Gentrix™ Surgical Matrix (Treatment), Permacol, Parietex, Progrip, Strattice Perforated, or Surgimend (Control)
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 26, 2026, 2:27 AM EDT
Not listed No phase listed Observational

Natural Orifice Translumenal Endoscopic Surgery (NOTES): Laparoscopic Assisted Transvaginal Ventral Hernia Repair

NCT01398215
View directory record Official record
Conditions
Umbilical Hernia, Ventral Hernia
Interventions
transvaginal NOTES ventral hernia repair
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Sep 26, 2026, 2:27 AM EDT
Completed No phase listed Observational

GERD Treatment With Transoral Incisionless Fundoplication (TIF) Following Hiatal Hernia Surgery

NCT03143608
View directory record Official record
Conditions
Gastro Esophageal Reflux
Interventions
Esophyx
Device
Lead sponsor
Peter G Mavrelis
Individual
Eligibility
18 Years to 80 Years
Enrollment
99 participants
Timeline
2014 – 2016
U.S. locations
2
States / cities
Merrillville, Indiana • Appleton, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 7, 2017 · Synced Sep 26, 2026, 2:27 AM EDT
Completed Not applicable Interventional Results available

Tacking Mesh Versus Self-fixating Mesh for Inguinal Hernia Repair

NCT03247985
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
PROLENE Polypropylene Tacking Mesh, ProGrip Self-fixating Mesh
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Sep 26, 2026, 2:27 AM EDT