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Showing 1–24 of 129 matching trials from the live ClinicalTrials.gov search.
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Conditions
Environmental Tobacco Smoke Exposure, Depression, Partner Abuse, Tobacco Smoking
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older · Female only
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed No phase listed Observational

Overcontrol and Suicide in PTSD

NCT06355284
Conditions
Compulsive Personality Disorder, Stress Disorders, Post-Traumatic
Interventions
Functional MRI
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Recruiting Not applicable Interventional Accepts healthy volunteers

Project HOPEFUL: A PN-RCT With Implementation Science

NCT07475039
Conditions
Older Adults (50-90 Years), Mental Health, Depression and Suicide Ideation, Social Functioning, Quality of Life, Thwarted Belongingness, Perceived Burdensomeness
Interventions
Standardized and manualized warm calls from providers trained in the BE training, Standardized and manualized warm calls from providers trained in the BE training + ASIST training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Completed No phase listed Observational Accepts healthy volunteers Results available

Oocyte Cryopreservation Registry (HOPE Registry)

NCT00699400
Conditions
Oocyte Cryopreservation
Interventions
Not listed
Lead sponsor
EMD Serono
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
15
States / cities
Fountain Valley, California • Laguna Hills, California • Newport Beach, California + 11 more
Completed Not applicable Interventional Results available

Piloting Pathways With Lung Cancer Patients

NCT04161157
Conditions
Metastatic Lung Cancer
Interventions
Pathways
Behavioral
Lead sponsor
Laurie McLouth
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

Forging Hopeful Futures to Reduce Youth Violence

NCT05743478
Conditions
Violence in Adolescence, Racism, Adolescent Behavior, Coping Skills, Communication, Social, Communication, Personal, Violence, Sexual, Violence, Non-accidental, Violence, Physical, Violence, Gender-Based
Interventions
Forging Hopeful Futures, Wellness Check-ins
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 19 Years
Enrollment
542 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Pittsburgh, Pennsylvania
Conditions
Traumatic Brain Injury, Hopelessness, Suicide
Interventions
Window to Hope, Waitlist Control
Other
Lead sponsor
Lisa Brenner
Federal
Eligibility
18 Years to 89 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Results available

HOPE Pilot for Veterans With Complex Diabetes

NCT01274715
Conditions
Diabetes, Depression
Interventions
Behavioral Health Coaching
Behavioral
Lead sponsor
Michael E. DeBakey VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Houston, Texas
Recruiting No phase listed Observational

Expanding HOPE Liver

NCT07778459
Conditions
HIV Infection, Liver Transplant
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Baltimore, Maryland • New York, New York
Conditions
HIV, AIDS, Substance Abuse, Inpatient
Interventions
Patient Navigation (PN) Group, Patient Navigator Plus Contingency Management (PN+CM) Group
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
801 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
12
States / cities
Birmingham, Alabama • Torrance, California • Miami, Florida + 8 more
Conditions
Stress
Interventions
Not listed
Lead sponsor
Creighton University
Other
Eligibility
3 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Cancer, Quality of Life, Anxiety, Depression, Hope, Coping Skills, Communication
Interventions
Promoting Resilience in Stress Management (PRISM)
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
12 Years to 24 Years
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • Pittsburgh, Pennsylvania + 2 more
Conditions
Chronic Pelvic Pain, Pudendal Neuralgia
Interventions
Saluda Evoke Smart SCS System
Device
Lead sponsor
Ainsworth Institute of Pain Management
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Phase 2 Interventional Results available

Halt cardiomyOPathy progrEssion in Duchenne (HOPE-OLE)

NCT06304064
Conditions
Duchenne Muscular Dystrophy
Interventions
Allogeneic Cardiosphere-Derived Cells (CAP-1002)
Biological
Lead sponsor
Capricor Inc.
Industry
Eligibility
12 Years and older · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Gainesville, Florida • Cincinnati, Ohio
Conditions
End Stage Renal Disease, Chronic Pain, Opioid Dependence
Interventions
Pain Coping Skills Training (PCST), Buprenorphine
Behavioral · Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
16
States / cities
West Haven, Connecticut • Chicago, Illinois • Boston, Massachusetts + 11 more
Conditions
Lung Cancer
Interventions
Pathways, Enhanced Usual Care
Behavioral
Lead sponsor
Laurie McLouth
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients, Traumatic Brain Injury (TBI); Concussion, Initial Encounter, Traumatic Brain Injury (TBI); Concussion, Subsequent Encounter, Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With Persistent Cognitive Deficits
Interventions
MUSE Stem Cell Therapy
Biological
Lead sponsor
Healing Hope International
Other
Eligibility
6 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2036
U.S. locations
1
States / cities
Houston, Texas
Conditions
Giant Axonal Neuropathy (GAN)
Interventions
scAAV9/JeT-GAN
Genetic
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years to 25 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Recurrent Ovarian Carcinoma
Interventions
Behavioral Intervention, Electronic Health Record Review, Interview, Survey Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Lung Cancer, Smoking Behaviors, Diagnosis
Interventions
Educational Lung Cancer Screening (LCS) Video
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Anxiety
Interventions
Digital CBT
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Conditions
Cancer, Exercise Test, Fatigue, Mood, Quality of Life, Biomarkers
Interventions
H4H fitness program
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Oral Feeding Outcomes, Neurodevelopment Outcome
Interventions
H-HOPE
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
1 Week to 8 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Not applicable Interventional Accepts healthy volunteers

Delivering HOPE (Helping Women Optimize Prenatal Equity)

NCT06814509
Conditions
Gestational Weight Gain, Diet, Healthy, Gestational Hypertension, Gestational Diabetes, Pregnancy Complications
Interventions
Enhanced Standard of Care (ESoC), Delivering HOPE
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
16 Years to 44 Years · Female only
Enrollment
1,440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
8
States / cities
Corning, Arkansas • Lavaca, Arkansas • Marianna, Arkansas + 5 more