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Showing 1–24 of 138 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hydration Status Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Nuun SPORT on Subjective Exercise Performance in Male and Female Runners

NCT05510791
View directory record Official record
Conditions
Hydration
Interventions
Nuun Sport Drink, Control
Dietary Supplement
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Jul 21, 2026, 6:05 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Hydrate Heroes for Improving Brain Function & Mood

NCT07241260
View directory record Official record
Conditions
Hydration Status
Interventions
Hydrate Heroes (6 packets), Hydrate Heroes (3 packets)
Dietary Supplement
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Rate and/or Presence of Dextrose on the Labor Course of Nulliparas

NCT01904617
View directory record Official record
Conditions
Length of Labor, Second Stage of Labor, Intravenous Hydration of Labor
Interventions
Dextrose, Normal Saline
Other
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2015 · Synced Jul 21, 2026, 6:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

An Open Label Direct-to-Consumer Study Assessing the Impact of Health and Wellness Products on GI Health and Related Health Outcomes

NCT07563855
View directory record Official record
Conditions
Health, Wellness, Quality of Life
Interventions
A ready-to-mix beverage containing protein, fiber, and electrolytes
Dietary Supplement
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
21 Years to 75 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 21, 2026, 6:05 PM EDT
Terminated No phase listed Observational

Comparison of Body Hydration State in Hemodialysis Patients

NCT01814254
View directory record Official record
Conditions
Hemodialysis, Chronic Kidney Disease
Interventions
Not listed
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hydration Factor Study for the Stayhealthy BC3

NCT01209936
View directory record Official record
Conditions
Body Composition
Interventions
D2O
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 80 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2023 · Synced Jul 21, 2026, 6:05 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Caregiver Assessments of the Quality of Home Hospice Care

NCT00895024
View directory record Official record
Conditions
Advanced Cancer
Interventions
Phone Interview/Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2020 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Phase 1Phase 2 Interventional

Effects of 2% IDL Lotion on Skin Hydration and Transepidermal Water Loss in Females With Dry Skin

NCT04253704
View directory record Official record
Conditions
Xerosis Cutis
Interventions
IDL lotion, Control lotion
Combination Product
Lead sponsor
Shyla Cantor
Industry
Eligibility
35 Years to 57 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Blauvelt, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional

Increasing Water Access and Appeal in Community Recreation Centers

NCT03637465
View directory record Official record
Conditions
Health Behavior
Interventions
Hydrate Philly
Behavioral
Lead sponsor
Philadelphia Department of Public Health
Government
Eligibility
3 Years to 100 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2019 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Hydration on Exercise Performance - ODIN

NCT02980939
View directory record Official record
Conditions
Dehydration
Interventions
iv fluid infusion
Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Phase 4 Interventional Results available

A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis

NCT01065714
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Hydrogel vehicle, Eucerin Lotion
Drug
Lead sponsor
Derm Research, PLLC
Other
Eligibility
12 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Jul 21, 2026, 6:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Beverage Hydration Index of Different Solutions

NCT07507344
View directory record Official record
Conditions
Hydration
Interventions
Hydramin hydration solution, Carbohydrate and Electrolyte hydration solution, Water
Dietary Supplement
Lead sponsor
University of Memphis
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of a Dietary Supplement on Parameters of Skin Aging in Men and Women

NCT06083402
View directory record Official record
Conditions
Skin Aging
Interventions
HyaCera™, Placebo
Dietary Supplement
Lead sponsor
Natals, Inc. dba Ritual
Industry
Eligibility
25 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Raritan, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Jul 21, 2026, 6:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Hydration and Rate of Cesarean Delivery Among Nulliparous

NCT01944787
View directory record Official record
Conditions
Pregnancy
Interventions
Routine, IV Hydration at 250cc hour
Other
Lead sponsor
Chauhan, Suneet P., M.D.
Individual
Eligibility
18 Years to 55 Years · Female only
Enrollment
670 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Campbell, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2013 · Synced Jul 21, 2026, 6:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes

NCT06212518
View directory record Official record
Conditions
Dehydration
Interventions
GENPOP ad libitum fluid intake, GENPOP fluid restriction, ATHLETE ad libitum fluid intake, ATHLETE restricted fluid intake
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
14 Years to 65 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
4
States / cities
Bradenton, Florida • Chicago, Illinois • Valhalla, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Glycerol-Electrolyte Beverage on Fluid Balance in Healthy Euhydrated Men and Women

NCT07217834
View directory record Official record
Conditions
Fluid Balance
Interventions
Placebo beverage, kiwi-strawberry flavor, Experimental glycerol beverage, kiwi-strawberry flavor
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Recombinant Hyaluronidase in Out-of-Hospital Setting: The EASI Access Trial

NCT00386386
View directory record Official record
Conditions
Mass Casualty Incident, Dehydration
Interventions
hypodermoclysis via recombinant hyaluronidase-facilitated subcutaneous infusion
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2008 · Synced Jul 21, 2026, 6:05 PM EDT
Withdrawn Phase 2 Interventional

Dipyridamole/Magnesium To Improve Sickle Cell Hydration

NCT00276146
View directory record Official record
Conditions
Anemia, Sickle Cell
Interventions
oral dipyridamole, oral magnesium, or a combination of both
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years and older
Timeline
Started 2005
U.S. locations
3
States / cities
Detroit, Michigan • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2013 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial to Evaluate Safety and Tolerability of a Novel Hydration Drink in Healthy Volunteers

NCT05428748
View directory record Official record
Conditions
Tolerance
Interventions
1 serving of test product, 2 servings of test product, 3 servings of test product, Placebo
Other
Lead sponsor
Liquid I.V.
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Proprietary Water on Physiological and Perceptual Responses

NCT05451446
View directory record Official record
Conditions
Hydration, Dehydration
Interventions
proprietary water, Active comparator, Placebo
Dietary Supplement · Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 50 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial to Evaluate the Efficacy of Skin Products to Improve Skin Quality and Health

NCT06853899
View directory record Official record
Conditions
Skin Hydration, Skin Aging
Interventions
Truology A2, Truology C-Boost, Truology Barrier Restore
Dietary Supplement
Lead sponsor
Truology
Industry
Eligibility
35 Years to 55 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Jul 21, 2026, 6:05 PM EDT
Active, not recruiting Not applicable Interventional

Xerosis and Use of Topical Moisturizer

NCT04341623
View directory record Official record
Conditions
Xerosis Due to Atopic Dermatitis
Interventions
Cetaphil Pro Eczema moisturizer, Electronic interaction, GPSkin
Other · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Jul 21, 2026, 6:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Adding Glycerol to Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest

NCT06654557
View directory record Official record
Conditions
Fluid Balance
Interventions
Placebo beverage, kiwi-strawberry flavor (Part 1 and Part 2), 0% carbohydrate electrolyte solution with glycerol beverage (Part 1 only), 0% carbohydrate electrolyte solution without glycerol beverage (Part 1 only), 1% carbohydrate electrolyte solution with glycerol beverage (Parts 1 and 2), 6% carbohydrate electrolyte solution with glycerol beverage (Parts 1 and 2), 6% carbohydrate electrolyte solution without glycerol beverage (Part 2 only), 2% carbohydrate electrolyte solution without glycerol beverage (Part 2 only)
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 50 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Jul 21, 2026, 6:05 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Boluses of Ringer's in Surgical Kids (BRiSK Study)

NCT05285371
View directory record Official record
Conditions
Dehydration in Children, Fluid Therapy
Interventions
Urinalysis (UA), Complete Metabolic Panel (CMP), Glucose Stick Test (d-Stick), Medical Chart Review
Diagnostic Test · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 21 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 21, 2026, 6:05 PM EDT