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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:13 AM EDT

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Showing 25–48 of 144 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hydration Status Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Utility of Transdermal Optical Imaging (TOI) as a Non-invasive Measure of Hydration Status: Phase 3a for Model Development

NCT06044610
View directory record Official record
Conditions
Dehydration
Interventions
GENPOP Passive dehydration (75% reduction in fluid intake, GENPOP Ad lib fluid intake, EXERCISE without fluid replacement, EXERCISE with fluid replacement
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Valhalla, New York • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2024 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Glycerol-Electrolyte Beverage on Fluid Balance in Healthy Euhydrated Men and Women

NCT07217834
View directory record Official record
Conditions
Fluid Balance
Interventions
Placebo beverage, kiwi-strawberry flavor, Experimental glycerol beverage, kiwi-strawberry flavor
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Natreon Healthy Skin Study - PrimaVie Supplement

NCT02762032
View directory record Official record
Conditions
Healthy
Interventions
PrimaVie Herbal Supplement 125, PrimaVie Herbal Supplement 250, Placebo
Dietary Supplement · Drug
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
3
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 21, 2026, 7:13 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes

NCT06212518
View directory record Official record
Conditions
Dehydration
Interventions
GENPOP ad libitum fluid intake, GENPOP fluid restriction, ATHLETE ad libitum fluid intake, ATHLETE restricted fluid intake
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
14 Years to 65 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
4
States / cities
Bradenton, Florida • Chicago, Illinois • Valhalla, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2024 · Synced Oct 21, 2026, 7:13 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise

NCT07298863
View directory record Official record
Conditions
Hydration Status, Substrate Metabolism During Exercise
Interventions
Part 1 - Exercise Trial, Part 1 - Experimental Trial, Part 2 - Oral Glucose Tolerance Test
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 35 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 21, 2026, 7:13 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Hydration, Ergonomic Risk, and Fatigue Across Multiple PepsiCo Facilities

NCT07848256
View directory record Official record
Conditions
Hydration Status and Ergonomic Risk in Frontline Workers
Interventions
Not listed
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Orlando, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Hydration on Exercise Performance - ODIN

NCT02980939
View directory record Official record
Conditions
Dehydration
Interventions
iv fluid infusion
Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oral Water Hydration to Prevent Post-Vaccination Presyncope

NCT02353390
View directory record Official record
Conditions
Presyncope, Syncope
Interventions
Oral Water Hydration
Other
Lead sponsor
Duke University
Other
Eligibility
11 Years to 21 Years
Enrollment
1,820 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2016 · Synced Oct 21, 2026, 7:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Collection of Anatomical and Reference Data for Development of a Novel Non-Invasive Lung Hydration Status Technology

NCT02426593
View directory record Official record
Conditions
Healthy
Interventions
IMED-4
Device
Lead sponsor
Intersection Medical, Inc.
Industry
Eligibility
30 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2015 · Synced Oct 21, 2026, 7:13 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Reference Values and Determinants of Hydration in Children 3-13 y

NCT02937038
View directory record Official record
Conditions
Dehydration
Interventions
Not listed
Lead sponsor
Arizona State University
Other
Eligibility
3 Years to 13 Years
Enrollment
1,454 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Tolerability of a Novel Amino-acid Based Hydration Drink in Healthy Volunteers

NCT05592951
View directory record Official record
Conditions
Safety, Tolerance
Interventions
Crystal Light (once serving), Liquid IV with amino acids (one serving), Liquid IV with amino acids (two servings), Liquid IV with amino acids (three servings)
Dietary Supplement
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Trial Assessing the Impact on Facial Skin Quality, Hydration, and Skin Barrier of Three (3) Hydrafacial Treatments in Adults of All Skin Types.

NCT05932732
View directory record Official record
Conditions
Cutis Laxa Facialis, Xeroderma
Interventions
HydraFacial Syndeo System, ReGen-GF, HydraFacial Elite MD System
Device · Drug
Lead sponsor
Austin Institute for Clinical Research
Network
Eligibility
30 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Houston, Texas • Pflugerville, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of the Beverage Hydration Index of Different Solutions

NCT06733532
View directory record Official record
Conditions
Hydration
Interventions
Berry Propel Fitness Water, Essentia Hydroboost Raspberry Pomegranate, Smart Water
Dietary Supplement
Lead sponsor
University of Memphis
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 21, 2026, 7:13 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Ovolux Beauty From Within Trial#2

NCT07188051
View directory record Official record
Conditions
Skin Sagging, Skin Wrinkling, Skin Dryness
Interventions
Ovolux brand eggshell membrane powder, Placebo
Dietary Supplement
Lead sponsor
ESM Technologies, LLC
Industry
Eligibility
35 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 21, 2026, 7:13 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Physician Perceptions About Parenteral Hydration in Latin America and Spain

NCT01011140
View directory record Official record
Conditions
Dehydration, Advanced Cancers
Interventions
Survey
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Boluses of Ringer's in Surgical Kids (BRiSK Study)

NCT05285371
View directory record Official record
Conditions
Dehydration in Children, Fluid Therapy
Interventions
Urinalysis (UA), Complete Metabolic Panel (CMP), Glucose Stick Test (d-Stick), Medical Chart Review
Diagnostic Test · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 21 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hydration Intervention in Children

NCT04265300
View directory record Official record
Conditions
Dehydration in Children
Interventions
Creative Roots
Dietary Supplement
Lead sponsor
University of Connecticut
Other
Eligibility
7 Years to 12 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effects of Increased IV Hydration on Nulliparous Women Undergoing an Induction of Labor

NCT02989571
View directory record Official record
Conditions
Labor; Forced or Induced, Affecting Fetus or Newborn
Interventions
Intravenous normal saline administered at 250ml/hr, Intravenous normal saline administered at 125ml/hr
Drug
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2023 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Open Label Direct-to-Consumer Study Assessing the Impact of Health and Wellness Products on GI Health and Related Health Outcomes

NCT07563855
View directory record Official record
Conditions
Health, Wellness, Quality of Life
Interventions
A ready-to-mix beverage containing protein, fiber, and electrolytes
Dietary Supplement
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
21 Years to 75 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 21, 2026, 7:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes

NCT02121184
View directory record Official record
Conditions
Pregnancy, Labor Pain
Interventions
Routine oxytocin, Half-dose oxytocin
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 21, 2026, 7:13 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

An Open Label Trial Assessing the Impact of a Hydration Formula on Overall Health

NCT07206979
View directory record Official record
Conditions
Hydration
Interventions
Hydration Active Product 1, Hydration Active Product 2, Hydration Active Product 3
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years to 105 Years
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Corneal Biomechanics With Hydration in Normal and LASIK Eyes

NCT01183702
View directory record Official record
Conditions
Laser Corneal Surgery
Interventions
LASIK surgery, No Intervention
Procedure · Other
Lead sponsor
Deb Grzybowski
Other
Eligibility
18 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 13, 2017 · Synced Oct 21, 2026, 7:13 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of SPM™ Topical Cosmetic Application on Skin Appearance, Hydration, and Barrier Support in Healthy Adults

NCT07236736
View directory record Official record
Conditions
Healthy Skin, Skin Hydration
Interventions
Skin biopsy, Corneometer® Measurement, Tewameter® Measurement
Procedure · Other
Lead sponsor
Biocoz Global Pte. Ltd.
Industry
Eligibility
20 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health

NCT03769779
View directory record Official record
Conditions
Aging, Wrinkle, Skin Elasticity, Healthy, Hydration
Interventions
FloraGLO Lutein, Safflower Oil
Dietary Supplement
Lead sponsor
Kemin Foods LC
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Port Chester, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Oct 21, 2026, 7:13 AM EDT