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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:26 PM EDT

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Showing 1–24 of 100 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hydrocephalus Clear all
Not listed Phase 4 Interventional

ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study

NCT01881711
View directory record Official record
Conditions
Suspected CSF Shunt Obstruction
Interventions
ShuntCheck-Micro-Pumper (SCMP), Imaging
Device
Lead sponsor
NeuroDx Development
Industry
Eligibility
35 Months to 29 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
11
States / cities
Wilmington, Delaware • Washington D.C., District of Columbia • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Oct 20, 2026, 2:26 PM EDT
Recruiting No phase listed Observational

Diagnostic Accuracy of ShuntCheck Compared to Radionuclide Shunt: Patency in Patients With Normal Pressure Hydrocephalus

NCT04309487
View directory record Official record
Conditions
Hydrocephalus, Normal Pressure
Interventions
ShuntCheck
Diagnostic Test
Lead sponsor
University of South Florida
Other
Eligibility
40 Years and older
Enrollment
20 participants
Timeline
2020 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 20, 2026, 2:26 PM EDT
Withdrawn Phase 4 Interventional

ShuntCheck Accuracy in Detecting Shunt Obstruction Normal Pressure Hydrocephalus (NPH) Patients

NCT00793416
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
Shunt flow detection
Device
Lead sponsor
NeuroDx Development
Industry
Eligibility
35 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 29, 2013 · Synced Oct 20, 2026, 2:26 PM EDT
Active, not recruiting Not applicable Interventional

HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

NCT04177914
View directory record Official record
Conditions
Hydrocephalus
Interventions
Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization (ETV+CPC), Ventriculoperitoneal Shunt
Procedure · Device
Lead sponsor
University of Utah
Other
Eligibility
1 Day to 104 Weeks
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
18
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 15 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 2:26 PM EDT
Completed No phase listed Observational

Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage

NCT01799018
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Cerebral Vasospasm, Hydrocephalus
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2014 · Synced Oct 20, 2026, 2:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics

NCT04099823
View directory record Official record
Conditions
Hydrocephalus, Alzheimer Disease
Interventions
MRI screening form, Urine pregnancy test, MR brain
Other · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 20, 2026, 2:26 PM EDT
Enrolling by invitation Not applicable Interventional

Non-Invasive Pressure Monitor for Neonates & Infants at Risk of Developing Hydrocephalus

NCT06310213
View directory record Official record
Conditions
Hydrocephalus in Infants
Interventions
Non-Invasive Pressure Monitor
Device
Lead sponsor
Indiana University
Other
Eligibility
0 Months to 12 Months
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 20, 2026, 2:26 PM EDT
Completed No phase listed Observational

Cerebral Perfusion, Oxygenation, Electrical Activity

NCT00747682
View directory record Official record
Conditions
Post-Hemorrhagic Hydrocephalus
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 24, 2010 · Synced Oct 20, 2026, 2:26 PM EDT
Terminated Not applicable Interventional

Pilot Study to Evaluate the CereVasc® EShunt® System in the Treatment of Communicating Hydrocephalus

NCT05501002
View directory record Official record
Conditions
Hydrocephalus, Hydrocephalus, Communicating
Interventions
eShunt® Implant
Device
Lead sponsor
CereVasc Inc
Industry
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
New Haven, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 20, 2026, 2:26 PM EDT
Completed Not applicable Interventional Results available

Quantitative Characterization of Safe Irrigation for Ventricular Shunt Catheters

NCT02651337
View directory record Official record
Conditions
Hydrocephaly
Interventions
Cerebrospinal Fluid (CSF) Drainage
Device
Lead sponsor
Alcyone Therapeutics, Inc
Industry
Eligibility
30 Days to 35 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 20, 2026, 2:26 PM EDT
Completed No phase listed Observational

Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus

NCT00600795
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
CSF collection
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 20, 2026, 2:26 PM EDT
Terminated No phase listed Observational

Functional and Non-Functional CSF Shunt Flow Measured With a Second-Generation Wireless Thermal Device

NCT06506045
View directory record Official record
Conditions
Hydrocephalus
Interventions
FlowSense
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
8
States / cities
Orange, California • West Hollywood, California • Tampa, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 20, 2026, 2:26 PM EDT
Completed Not applicable Interventional

Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm Infants

NCT00875758
View directory record Official record
Conditions
Intraventricular Hemorrhage, Hydrocephalus
Interventions
Removal of CSF through ventricular access device, Removal of CSF through a ventricular access device
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 34 Weeks
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 20, 2026, 2:26 PM EDT
Recruiting Not applicable Interventional

Flow Detection in Open and Closed Shunt Valve Periods

NCT07478926
View directory record Official record
Conditions
Hydrocephalus
Interventions
Rhaeos Shunt Monitoring System
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 20, 2026, 2:26 PM EDT
Recruiting No phase listed Observational

Assessment of ShuntCheck Performance Characteristics in Asymptomatic Patients With Normal Pressure Hydrocephalus

NCT04011566
View directory record Official record
Conditions
Hydrocephalus, Normal Pressure
Interventions
ShuntCheck
Diagnostic Test
Lead sponsor
University of South Florida
Other
Eligibility
40 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 20, 2026, 2:26 PM EDT
Withdrawn No phase listed Observational

Head Circumference Growth in Children Who Develop Multiple Sclerosis Later in Life

NCT01377805
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Not listed
Lead sponsor
Genetic Disease Investigators
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Colleyville, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Oct 20, 2026, 2:26 PM EDT
Completed No phase listed Observational

Normal Pressure Hydrocephalus (NPH) Registry

NCT00233701
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
Not listed
Lead sponsor
Codman & Shurtleff
Industry
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
28
States / cities
Phoenix, Arizona • Los Angeles, California • Boulder, Colorado + 25 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2010 · Synced Oct 20, 2026, 2:26 PM EDT
Recruiting Not applicable Interventional

Examining the Feasibility of Using Pressure Gradient Regulated Automated Cerebral Spinal Fluid Drainage During External Lumbar Drain Trials

NCT07494812
View directory record Official record
Conditions
NPH (Normal Pressure Hydrocephalus)
Interventions
Intellidrop Automated CSF Drainage System
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
60 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 20, 2026, 2:26 PM EDT
Withdrawn No phase listed Observational

Diagnosing Malfunctioning Hydrocephalic Shunt Valves With a Flow Sensor

NCT00652249
View directory record Official record
Conditions
Hydrocephalus
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Up to 20 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 5, 2012 · Synced Oct 20, 2026, 2:26 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Bench Study of Transcutaneous Hydrocephalic Shunt Flow Sensor Alignment Accuracy and Repeatability

NCT00651950
View directory record Official record
Conditions
Hydrocephalus
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 5, 2012 · Synced Oct 20, 2026, 2:26 PM EDT
Recruiting No phase listed Observational

HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)

NCT00670735
View directory record Official record
Conditions
Pediatric Hydrocephalus
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 18 Years
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2029
U.S. locations
11
States / cities
Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 20, 2026, 2:26 PM EDT
Not listed No phase listed Observational

Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology

NCT04363658
View directory record Official record
Conditions
Hydrocephalus
Interventions
Not listed
Lead sponsor
Xiangya Hospital of Central South University
Other
Eligibility
16 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Oct 20, 2026, 2:26 PM EDT
Completed No phase listed Observational

Flow Measurements in Functional CSF Shunts and Off-Shunt Locations with a Second-Generation Thermal Device

NCT06524492
View directory record Official record
Conditions
Hydrocephalus
Interventions
FlowSense
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
Not listed
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
3
States / cities
Tampa, Florida • Chicago, Illinois • Rolling Meadows, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 20, 2026, 2:26 PM EDT
Completed No phase listed Observational

Study of Shunt Flow Sensor Accuracy in Extra-ventricular Drains.

NCT01108965
View directory record Official record
Conditions
Hydrocephalus, Nervous System Diseases, Infant, Newborn Diseases
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2016 · Synced Oct 20, 2026, 2:26 PM EDT