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ClinicalTrials.gov public records Last synced Oct 20, 2026, 3:14 PM EDT

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Showing 25–48 of 100 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hydrocephalus Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy

NCT03230032
View directory record Official record
Conditions
Infant Development, Infant,Premature, Hydrocephalus, Neonatal Encephalopathy, Infarction, PVL, Thrombosis, Intraventricular Hemorrhage
Interventions
pacifier-activated device
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
32 Weeks to 12 Months
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 20, 2026, 3:14 PM EDT
Not yet recruiting Not applicable Interventional

Assessment of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device in Asymptomatic Patients

NCT06410885
View directory record Official record
Conditions
Hydrocephalus
Interventions
Thermal Anisotropy Measurement Device
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
2 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 20, 2026, 3:14 PM EDT
Not yet recruiting Not applicable Interventional

Study of Shunt Flow Under Different Valve Settings Using a Wireless Sensor

NCT07679035
View directory record Official record
Conditions
Hydrocephalus
Interventions
Rhaeos Shunt Monitoring System (RSMS), ShuntCheck III
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
Not listed
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 20, 2026, 3:14 PM EDT
Not listed Phase 3 Interventional

The CSF Shunt Entry Site Trial

NCT02425761
View directory record Official record
Conditions
Hydrocephalus
Interventions
Ventriculoperitoneal shunt insertion surgery
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
1 Day to 17 Years
Enrollment
448 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
11
States / cities
Birmingham, Alabama • Los Angeles, California • Denver, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Oct 20, 2026, 3:14 PM EDT
Completed Phase 3 Interventional Results available

A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System.

NCT00196196
View directory record Official record
Conditions
Hydrocephalus, Normal Pressure Hydrocephalus
Interventions
Codman VPV System
Device
Lead sponsor
Codman & Shurtleff
Industry
Eligibility
Not listed
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
8
States / cities
Phoenix, Arizona • Orlando, Florida • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated May 28, 2012 · Synced Oct 20, 2026, 3:14 PM EDT
Terminated Not applicable Interventional Results available

Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus

NCT00613886
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
Programmable Shunt Insertion (Codman, Medtronic), Assessments in physical therapy, occupational therapy, and speech therapy
Device · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 20, 2026, 3:14 PM EDT
Completed No phase listed Observational Results available

Assessment of CSF Shunt Flow With Thermal Measurements A

NCT05015751
View directory record Official record
Conditions
Hydrocephalus
Interventions
Thermal Anisotropy Measurement Device
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
Not listed
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Oakland, California • San Francisco, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 20, 2026, 3:14 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Formative Usability Assessment of Wireless Thermal Anisotropy Devices

NCT06040697
View directory record Official record
Conditions
Hydrocephalus
Interventions
Thermal Anisotropy
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
5 Years to 80 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 20, 2026, 3:14 PM EDT
Completed No phase listed Observational Results available

Assessment of CSF Shunt Flow With Thermal Measurements B

NCT05432986
View directory record Official record
Conditions
Hydrocephalus
Interventions
Thermal Anisotropy Measurement Device
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
Not listed
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
10
States / cities
Oakland, California • San Francisco, California • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Oct 20, 2026, 3:14 PM EDT
Terminated No phase listed Observational Results available

Strata Programmable CSF Shunt Valve Study

NCT02737163
View directory record Official record
Conditions
Hydrocephalus
Interventions
Not listed
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
1 Year to 21 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 20, 2026, 3:14 PM EDT
Completed No phase listed Observational

Study of Ultrasound of the Eye for Children With Suspected Shunt Failure

NCT00743457
View directory record Official record
Conditions
Hydrocephalus
Interventions
Ocular Ultrasound
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
6 Months to 18 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2012 · Synced Oct 20, 2026, 3:14 PM EDT
Completed No phase listed Observational

Shunt Outcomes of Post-Hemorrhagic Hydrocephalus

NCT01480349
View directory record Official record
Conditions
Post-Hemorrhagic Hydrocephalus
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 180 Days
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
6
States / cities
Birmingham, Alabama • St Louis, Missouri • Pittsburgh, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 26, 2017 · Synced Oct 20, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Light Therapy Device for Neonatal Intraventricular Hemorrhage Grade 3 and 4

NCT06797219
View directory record Official record
Conditions
Intraventricular Hemorrhage of Prematurity, Hydrocephalus
Interventions
Low Level Laser Therapy for Intraventricular Hemorrhage of Prematurity
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
0 Days to 1 Month
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Oct 20, 2026, 3:14 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies

NCT04020198
View directory record Official record
Conditions
Parkinson Disease, Multiple System Atrophy, Rapid Eye Movement Sleep Behavior Disorder, Normal Pressure Hydrocephalus
Interventions
Biomarker assay
Other
Lead sponsor
Stony Brook University
Other
Eligibility
50 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 20, 2026, 3:14 PM EDT
Completed Not applicable Interventional

Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging

NCT04436068
View directory record Official record
Conditions
Hydrocephalus, Neurological Disorder
Interventions
Hyperfine MRI scan
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 20, 2026, 3:14 PM EDT
Terminated No phase listed Observational

ETV Versus Shunt Surgery in Normal Pressure Hydrocephalus

NCT00946127
View directory record Official record
Conditions
Hydrocephalus
Interventions
Ventriculoperitoneal Shunt Placement, Endoscopic Third Ventriculostomy(ETV)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 3, 2012 · Synced Oct 20, 2026, 3:14 PM EDT
Completed No phase listed Observational

Establishing the Physiology of Syringomyelia

NCT00001327
View directory record Official record
Conditions
Arnold Chiari Deformity, Hydrocephalus, Syringomyelia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 20, 2026, 3:14 PM EDT
Completed Phase 4 Interventional

ShuntCheck Versus Radionuclide in Evaluating Shunt Function in Symptomatic NPH Patients

NCT01323764
View directory record Official record
Conditions
Hydrocephalus
Interventions
ShuntCheck test
Device
Lead sponsor
NeuroDx Development
Industry
Eligibility
35 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Oct 20, 2026, 3:14 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage

NCT01878136
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Cerebral Vasospasm, Cerebral Aneurysm, Hydrocephalus
Interventions
Tissue Plasminogen Activator
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 11, 2015 · Synced Oct 20, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Assessment of CSF Shunt Flow During Activities of Daily Living and Sleep With a Thermal Measurement Device

NCT07050628
View directory record Official record
Conditions
Hydrocephalus
Interventions
wireless thermal anisotropy measurement device
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
2 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 20, 2026, 3:14 PM EDT
Active, not recruiting No phase listed Observational

Improving Infant Hydrocephalus Outcomes in Uganda

NCT03650101
View directory record Official record
Conditions
Hydrocephalus
Interventions
ETV/CPC
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Day to 180 Days
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 20, 2026, 3:14 PM EDT
Not listed Not applicable Interventional

Physician Preference Study of ShuntCheck - Madsen

NCT00583336
View directory record Official record
Conditions
CSF Flow Through the Shunt of a Hydrocephalus Patient
Interventions
ShuntCheck
Device
Lead sponsor
NeuroDx Development
Industry
Eligibility
Up to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Oct 20, 2026, 3:14 PM EDT
Terminated No phase listed Observational

Myelin Imaging Changes In Patients With Neurosurgical Diseases

NCT03698838
View directory record Official record
Conditions
Hydrocephalus in Children, Epilepsy, Craniosynostoses, Traumatic Brain Injury
Interventions
McDESPOT
Device
Lead sponsor
Memorial Healthcare System
Other
Eligibility
Up to 19 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Hollywood, Florida
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 20, 2026, 3:14 PM EDT