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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

A Multifactorial Exercise Program to Reduce Falls in People With Parkinson Disease

NCT02302144
View directory record Official record
Conditions
Parkinson Disease
Interventions
Balance & Strengthening Exercises
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Recruiting Phase 2 Interventional

A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)

NCT07704840
View directory record Official record
Conditions
Post-Stroke Spasticity
Interventions
Administration of BMS-986368, Placebo
Drug
Lead sponsor
Alberto Esquenazi
Other
Eligibility
18 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Recruiting Not applicable Interventional

Functional Balance Intervention in Multiple Sclerosis

NCT06341023
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Functional Balance Intervention, Stretching
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Dose Escalation Study of Intravenous Baclofen in Healthy Adult Volunteers

NCT01931319
View directory record Official record
Conditions
Safety and Pharmacokinetics of Intravenous Baclofen
Interventions
Intravenous baclofen
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Sep 14, 2026, 9:35 PM EDT
Recruiting No phase listed Observational

Outcomes of Neurosurgical Tone Management

NCT07817745
View directory record Official record
Conditions
Spastic/Dystonic Quadriplegia, Cerebral Palsy (CP)
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 25 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

Spinal Cord Stimulation to Augment Activity Based Therapy

NCT03240601
View directory record Official record
Conditions
Transcutaneous Spinal Stimulation, Walking, Spasticity, Human, Spinal Cord Injuries
Interventions
Transcutaneous spinal stimulation
Device
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Botox and Vibration on Bone in Children With Cerebral Palsy

NCT01803464
View directory record Official record
Conditions
Cerebral Palsy, Muscle Spasticity
Interventions
Low-magnitude vibration, Botox
Device · Drug
Lead sponsor
University of Delaware
Other
Eligibility
2 Years to 12 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
2
States / cities
Newark, Delaware • Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Sep 14, 2026, 9:35 PM EDT
Terminated No phase listed Observational

A Study of Movement Disorders Using the QMAT At-Home Testing Device

NCT01905839
View directory record Official record
Conditions
Movement Disorders, Parkinson's Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 90 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Sep 14, 2026, 9:35 PM EDT
Recruiting No phase listed Observational

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

NCT05354622
View directory record Official record
Conditions
Hereditary Spastic Paraplegia, Neurodegenerative Diseases, Pediatric Disorder, Spasticity, Muscle, Motor Neuron Disease, Movement Disorders
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Month to 30 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Not applicable Interventional

Influence of Wearable Intensive Nerve Stimulation on Spasticity and Function in Persons With Spinal Cord Injury

NCT04130295
View directory record Official record
Conditions
Spinal Cord Injuries, Spasticity, Muscle
Interventions
Wearable intensive nerve stimulator
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Sep 14, 2026, 9:35 PM EDT
Terminated No phase listed Observational

Long-term Surveillance of the MedStream Programmable Infusion System

NCT01712087
View directory record Official record
Conditions
Spasticity
Interventions
MedStream Programmable Infusion System
Device
Lead sponsor
Codman & Shurtleff
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Worcester, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Not applicable Interventional

The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury

NCT00223873
View directory record Official record
Conditions
Spinal Cord Injury, Muscle Spasticity
Interventions
Penile Vibratory Stimulation
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Not applicable Interventional

Physiological Changes Induced Through MEP Conditioning in People With SCI

NCT04286191
View directory record Official record
Conditions
Spinal Cord Injuries, Neurological Injury, Paralysis, Spasticity, Muscle
Interventions
Operant Conditioning, Control Group
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 14, 2026, 9:35 PM EDT
Completed No phase listed Observational

A Study to Collect Participants Experience of Living With Adult Upper Limb (AUL) Spasticity and to Assess the Arm Activity Measure (ArmA)

NCT05546190
View directory record Official record
Conditions
Spastic Hemiparesis, Muscle Spasticity
Interventions
Not listed
Lead sponsor
Ipsen
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Downey, California • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Phase 1Phase 2 Interventional

Oral Baclofen Pharmacokinetics and Pharmacodynamics in Children With Spasticity

NCT00607542
View directory record Official record
Conditions
Spasticity, Cerebral Palsy
Interventions
baclofen
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
2 Years to 16 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
11
States / cities
Chicago, Illinois • New Orleans, Louisiana • Baltimore, Maryland + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2011 · Synced Sep 14, 2026, 9:35 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Robot Aided Rehabilitation - Multi-joint Evaluations

NCT02359812
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 85 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Phase 3 Interventional Results available

BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity

NCT01603615
View directory record Official record
Conditions
Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
Interventions
Botulinum Toxin Type A
Biological
Lead sponsor
Allergan
Industry
Eligibility
2 Years to 17 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
24
States / cities
Pasadena, California • Pomona, California • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Sep 14, 2026, 9:35 PM EDT
Completed No phase listed Observational

Classification of Cerebral Palsy Subtypes

NCT00072800
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 14, 2026, 9:35 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.

NCT04752774
View directory record Official record
Conditions
Spasticity
Interventions
Corabotase, Placebo, Dysport
Biological · Drug
Lead sponsor
Ipsen
Industry
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
5
States / cities
Downey, California • Overland Park, Kansas • Farmington Hills, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Recruiting Not applicable Interventional

Leg Stretching Using an Exoskeleton on Demand for People With Spasticity

NCT05926596
View directory record Official record
Conditions
Spasticity, Movement Disorders, Spinal Cord Injury
Interventions
Wearable Robotic Exoskeleton
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Not yet recruiting Early Phase 1 Interventional

Collagenase Injection for Spasticity Management

NCT07693569
View directory record Official record
Conditions
Spasticity
Interventions
XIAFLEX Collagenase injection
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Not yet recruiting Not applicable Interventional

Measuring Pelvic Floor Muscle Fitness Before and After Treatment

NCT07605598
View directory record Official record
Conditions
Myofacial Pain, Pelvic Pain, Myofascial Pelvic Pain, Chronic Pelvic Pain
Interventions
Near Infrared Imaging
Diagnostic Test
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 14, 2026, 9:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Using Telemedicine to Improve Spasticity Diagnosis Rates

NCT03211390
View directory record Official record
Conditions
Spasticity, Muscle, Muscular Diseases, Musculoskeletal Disease, Muscle Hypertonia, Muscle Spasticity, Neuromuscular Manifestations, Signs and Symptoms, Nervous System Diseases, Neurologic Manifestations
Interventions
Neurological Examination, Teleneurological Examination
Diagnostic Test
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 8, 2018 · Synced Sep 14, 2026, 9:35 PM EDT
Completed Phase 3 Interventional Results available

BOTOX® Treatment in Adult Patients With Post-Stroke Lower Limb Spasticity

NCT01575054
View directory record Official record
Conditions
Muscle Spasticity
Interventions
botulinum toxin Type A, Normal Saline
Biological · Drug
Lead sponsor
Allergan
Industry
Eligibility
18 Years to 85 Years
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Downey, California • Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Sep 27, 2016 · Synced Sep 14, 2026, 9:35 PM EDT