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ClinicalTrials.gov public records Last synced Jul 22, 2026, 10:41 AM EDT

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Showing 1–24 of 50 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hypopnea Clear all
Completed Phase 3 Interventional Results available

Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome

NCT00228566
View directory record Official record
Conditions
Excessive Daytime Sleepiness, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)
Interventions
Armodafinil
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 65 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
43
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2013 · Synced Jul 22, 2026, 10:41 AM EDT
Enrolling by invitation No phase listed Observational

Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

NCT03062748
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jul 22, 2026, 10:41 AM EDT
Completed No phase listed Observational

Point-of-care-Ultrasound for Sleep Apnea

NCT04443582
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Rakesh Sondekoppam Vijayashankar
Other
Eligibility
18 Years to 85 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 27, 2022 · Synced Jul 22, 2026, 10:41 AM EDT
Not listed No phase listed Observational

Is My Sleep Tracker Tracking my Sleep?

NCT06174558
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Sleep Tracking Devices
Device
Lead sponsor
Respiratory Specialists
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Wyomissing, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Jul 22, 2026, 10:41 AM EDT
Not yet recruiting Not applicable Interventional

Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA).

NCT07613281
View directory record Official record
Conditions
Snoring, OSA - Obstructive Sleep Apnea
Interventions
Palatal Implant System
Device
Lead sponsor
Serene Sleep, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
San Francisco, California • Evans, Georgia
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study Will Test the Theory That Training With the Facial-Flex Exercise Device Will Improve Snoring in Patients

NCT01554904
View directory record Official record
Conditions
Primary Snoring, Sleep Apnea
Interventions
Facial-Flex
Device
Lead sponsor
Facial Concepts, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Phase 2 Interventional Results available

The Sleep, Liver Evaluation and Effective Pressure Study

NCT01482065
View directory record Official record
Conditions
Non Alcoholic Fatty Liver Disease, Obstructive Sleep Apnea
Interventions
CPAP (ResMed S9 autoset CPAP)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 3, 2017 · Synced Jul 22, 2026, 10:41 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

NCT04118387
View directory record Official record
Conditions
Sleep Disordered Breathing, Able Bodied
Interventions
Acetazolamide + supplemental oxygen + PAP therapy, Zolpidem + PAP therapy, Buspirone + PAP therapy
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Not applicable Interventional Results available

Effect of Added Varnum Mouthpiece on Pharyngeal Collapsibility and Sleep Apnea Severity in Mouth Breathers.

NCT02738255
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Varnum mouthpiece
Device
Lead sponsor
David Andrew Wellman
Other
Eligibility
21 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2022 · Synced Jul 22, 2026, 10:41 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Assessment of PPG & PAT to Detect Upper Airway Obstruction in Patients With Obstructive Sleep Apnea

NCT01831583
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Measurement of PPG waveforms, Measurement of Pulse Arrival Time (PAT)
Device
Lead sponsor
Sotera Wireless, Inc.
Industry
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Escondido, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2013 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Phase 4 Interventional Results available

The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea

NCT02714400
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Venlafaxine, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Not applicable Interventional Results available

Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)

NCT00750165
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
SleepStyle 200 Auto Series CPAP Humidifier
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Jul 22, 2026, 10:41 AM EDT
Recruiting No phase listed Observational

Pediatric Post-Approval Registry

NCT04457154
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Inspire Upper Airway Stimulation System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
18 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
8
States / cities
Aurora, Colorado • Atlanta, Georgia • Durham, North Carolina + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Phase 4 Interventional

Randomized Study of Provent Versus Sham Device to Treat Obstructive Sleep Apnea

NCT00772044
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea, OSA, OSAH
Interventions
Provent Professional Sleep Apnea Therapy Device, Sham Device
Device
Lead sponsor
Ventus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
17
States / cities
Glendale, Arizona • Phoenix, Arizona • Redwood City, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2010 · Synced Jul 22, 2026, 10:41 AM EDT
Completed No phase listed Observational

Improving the STOP-Bang Screening Questionnaire for Patients With Sleep Apnea

NCT01610648
View directory record Official record
Conditions
Sleep Apnea, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Not applicable Interventional Results available

Use of Capnography in EGD and Colonoscopy With Moderate Sedation.

NCT01994785
View directory record Official record
Conditions
Hypoxia, Apnea, Hypotension, Hypopnea
Interventions
Capnographic Monitoring
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Independence, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 10:41 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Undetected Sleep Apnea in the Postanesthesia Acute Care Unit (PACU)

NCT02166879
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Phase 4 Interventional Results available

Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression

NCT00518986
View directory record Official record
Conditions
Sleep Disorders, Obstructive Sleep Apnea, Major Depressive Disorder, Dysthymic Disorder
Interventions
armodafinil, placebo
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 65 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
62
States / cities
Jasper, Alabama • Phoenix, Arizona • Tucson, Arizona + 50 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2013 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Early Phase 1 Interventional

Promoting Continuous Positive Airway Pressure (CPAP) Adherence

NCT01335854
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Web-based Access to CPAP Data, Web-based Access to CPAP Data with Financial Incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2014 · Synced Jul 22, 2026, 10:41 AM EDT
Recruiting No phase listed Observational

A Prospective Study to Evaluate the WP in Comparison to PSG in Patients Suspected of Sleep Disorders

NCT06093633
View directory record Official record
Conditions
Sleep Disorder
Interventions
Not listed
Lead sponsor
Itamar-Medical, Israel
Industry
Eligibility
12 Years to 99 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Baltimore, Maryland • Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome

NCT00107809
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Modafinil
Drug
Lead sponsor
Cephalon
Industry
Eligibility
6 Years to 16 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
60
States / cities
Birmingham, Alabama • Tucson, Arizona • Fort Smith, Arkansas + 51 more
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Not applicable Interventional

Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

NCT04950894
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive, Apnea, Obstructive Sleep, Apnea+Hypopnea, Hypopnea, Sleep
Interventions
Hypoglossal Nerve Stimulation
Device
Lead sponsor
LivaNova
Industry
Eligibility
22 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
19
States / cities
Birmingham, Alabama • Tucson, Arizona • Roseville, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Not applicable Interventional Results available

DeVilbiss AutoAdjust With SmartFlex Comparative Study

NCT01203956
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
SmartFlex, Standard
Device
Lead sponsor
DeVilbiss Healthcare LLC
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Dallas, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Jul 22, 2026, 10:41 AM EDT
Completed Not applicable Interventional Results available

The Effects of Trazodone on Sleep Apnea Severity

NCT01817907
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Placebo pill, Trazodone
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Jul 22, 2026, 10:41 AM EDT