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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 3 Interventional

Efficacy and Safety of Tadalafil in Subjects With Erectile Dysfunction Caused by Spinal Cord Injury

NCT00421083
View directory record Official record
Conditions
Erectile Dysfunction, Spinal Cord Injuries
Interventions
tadalafil
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older · Male only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 24, 2007 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 4 Interventional

A Study Evaluating Vardenafil Compared to Placebo in Subjects With Erectile Dysfunction (ED) and Dyslipidemia

NCT00379756
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
LEVITRA (vardenafil), placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 64 Years · Male only
Enrollment
395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
65
States / cities
Fairhope, Alabama • Homewood, Alabama • Huntsville, Alabama + 61 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 4 Interventional Results available

A Study in Erectile Dysfunction

NCT01130532
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Tadalafil, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older · Male only
Enrollment
623 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
34
States / cities
Huntsville, Alabama • Lancaster, California • Newport Beach, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jan 3, 2013 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Compare the Blood Levels of Sildenafil Following Administration of an Experimental Tablet vs. the Conventional Oral Tablet in Healthy Subjects

NCT00866463
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Sildenafil
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 31, 2021 · Synced Sep 20, 2026, 1:12 AM EDT
Not listed Phase 2 Interventional

Safety and Efficacy Study of Oral Fispemifene for the Treatment of Sexual Dysfunction in Hypogonadal Men

NCT02443090
View directory record Official record
Conditions
Secondary Hypogonadism, Sexual Dysfunction, Erectile Dysfunction
Interventions
fispemifene, Placebo
Drug · Other
Lead sponsor
NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences, Inc.)
Industry
Eligibility
18 Years to 64 Years · Male only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
16
States / cities
Little Rock, Arkansas • San Diego, California • Bradenton, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2015 · Synced Sep 20, 2026, 1:12 AM EDT
Terminated Phase 2 Interventional

Efficacy & Safety of Single Dose Alprostadil Cream (2 Concentrations Enhancer) to Vehicle in Men w/Erectile Dysfunction

NCT01810575
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
WC3036-11F/Alprostadil in Vehicle 2.5%, WC3036-12F/Alprostadil in Vehicle 0.5%, WC3036-13P/Vehicle Only 0.5%
Drug
Lead sponsor
Warner Chilcott
Industry
Eligibility
40 Years and older · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Purchase, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2014 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 1 Interventional Results available

Shockwave Therapy and Platelet Rich Plasma for the Treatment of Erectile Dysfunction

NCT05048667
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Shock Wave therapy (SWT), Platelet Rich Plasma (PRP), Sham SWT, Placebo Saline
Device · Drug · Other
Lead sponsor
University of Miami
Other
Eligibility
30 Years to 80 Years · Male only
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 4 Interventional

Study Of Men With Mild To Moderate Erectile Dysfunction To Evaluate The Efficacy Of Viagra 8 Hours Post-Dose

NCT00143260
View directory record Official record
Conditions
Impotence
Interventions
Viagra (Sildenafil Citrate) 100 mg
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years to 70 Years · Male only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
25
States / cities
Birmingham, Alabama • Homewood, Alabama • Hoover, Alabama + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2021 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 3 Interventional Results available

Concomitant Use of PriLigy in Men Treated for Erectile Dysfunction

NCT01063855
View directory record Official record
Conditions
Erectile Dysfunction, Sexual Dysfunction
Interventions
Placebo, Dapoxetine, PDE5I (phosphodiesterase-5 inhibitor)
Drug
Lead sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Industry
Eligibility
18 Years and older · Male only
Enrollment
495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
19
States / cities
Decatur, Alabama • Huntsville, Alabama • Englewood, Colorado + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2013 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 2 Interventional Results available

L-Arginine Supplementation With or Without Enzyme Inhibitors Treating Erectile Function of Prostate Cancer Survivors

NCT01105130
View directory record Official record
Conditions
Male Erectile Disorder, Prostate Cancer, Radiation Toxicity
Interventions
Placebo, Oral L-Arginine
Other · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Male only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of an External Erectile Device in Transgender Man Following Phalloplasty

NCT03823014
View directory record Official record
Conditions
Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
Interventions
Elator
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Sep 20, 2026, 1:12 AM EDT
Recruiting Not applicable Interventional

Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease

NCT06065436
View directory record Official record
Conditions
Peyronie Disease, Erectile Dysfunction
Interventions
Collagenase Clostridium Histolyticum, Storz Duolith LiSWT
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 3 Interventional

Treatment of Erectile Dysfunction - Long Term Safety and Efficacy

NCT01065012
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Udenafil 50 mg, Udenafil 100 mg, Udenafil 150 mg, Placebo Matching 50 mg Udenafil, Placebo Matching 100 mg Udenafil, Placebo Matching 150 mg Udenafil
Drug
Lead sponsor
Warner Chilcott
Industry
Eligibility
19 Years and older · Male only
Enrollment
1,027 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
72
States / cities
Birmingham, Alabama • Homewood, Alabama • Huntsville, Alabama + 65 more
Source: ClinicalTrials.gov public record
Updated Apr 19, 2015 · Synced Sep 20, 2026, 1:12 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

IT Matters: The Erectile Restoration Registry

NCT04200937
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Tactra Malleable, Spectra™ Concealable Penile Prothesis, AMS Ambicor™ Inflatable Penile Prosthesis, AMS 700™ Inflatable Penile Prosthesis w/Momentary Squeeze (MS) Pump, AMS 700™ Inflatable Penile Prosthesis w/Tenacio™ Pump
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older · Male only
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2031
U.S. locations
21
States / cities
Los Angeles, California • Miami, Florida • Tampa, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 20, 2026, 1:12 AM EDT
Terminated Not applicable Interventional Results available

Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy

NCT00955929
View directory record Official record
Conditions
Penile Cancer, Erectile Dysfunction, Radical Prostatectomy
Interventions
Placebo QHS and sildenafil and questionnaires, Sildenafil and questionnaire, Trimix combination (Papavarine 30mg/mL Phentholamine 1mg/mL Prostaglandin E1 10 mcg/mmL) and questionnaires
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Sep 20, 2026, 1:12 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

The Role of Platelet Rich Plasma for Erectile Dysfunction

NCT04357353
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Platelet rich plasma, Placebo Sham Injection
Biological · Other
Lead sponsor
University of Nebraska
Other
Eligibility
50 Years to 80 Years · Male only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Sep 20, 2026, 1:12 AM EDT
Terminated Not applicable Interventional Results available

Penile Lengthening Pre-Penile Prosthesis Implantation

NCT03500406
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
RestoreX, Control
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Male only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Rochester, Minnesota • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 5, 2020 · Synced Sep 20, 2026, 1:12 AM EDT
Not listed Phase 4 Interventional

Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer

NCT00906269
View directory record Official record
Conditions
Impotence, Prostatic Neoplasms
Interventions
Sildenafil therapy plus post-NSRRP HBO2T, Sildenafil therapy plus sham post-NSRRP HBO2T
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2021
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 4 Interventional Results available

Effect of Testosterone in Men With Erectile Dysfunction

NCT00512707
View directory record Official record
Conditions
Erectile Dysfunction, Testosterone Deficiency, Diabetes
Interventions
Sildenafil citrate (open label), Testosterone gel, Placebo gel
Drug · Other
Lead sponsor
Boston University
Other
Eligibility
40 Years to 70 Years · Male only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Sep 20, 2026, 1:12 AM EDT
Not yet recruiting Phase 4 Interventional

IPP Placement & Intracavernosal Block

NCT07246642
View directory record Official record
Conditions
Erectile Dysfunction (ED)
Interventions
Exparel/bupivacaine mixture
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 3 Interventional

A New Sildenafil Oral Film in Patients With Erectile Dysfunction

NCT05490680
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Sildenafil Oral Film 25 mg, 50 mg, 75 mg or 100 mg, Placebo
Drug
Lead sponsor
IBSA Institut Biochimique SA
Industry
Eligibility
18 Years and older · Male only
Enrollment
488 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
18
States / cities
Foley, Alabama • Huntsville, Alabama • Little Rock, Arkansas + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 20, 2026, 1:12 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

NCT04684602
View directory record Official record
Conditions
Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease, Musculoskeletal Disorders, Neurodegenerative Disorders, Neurologic Disorders, Pulmonary Disorders, Sexual Dysfunction, Urologic Disorders, Viral Illness
Interventions
PrimePro™/ PrimeMSK™
Biological
Lead sponsor
Thomas Advanced Medical LLC
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Culver City, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2022 · Synced Sep 20, 2026, 1:12 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

To Evaluate The Effect Of Ketoconazole, Ritonavir and Erythromycin on the Safety and Pharmacokinetics of Avanafil

NCT00770042
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Ritonavir, Ketoconazole, Erythomycin, Avanafil
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
21 Years to 45 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 1, 2009 · Synced Sep 20, 2026, 1:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Changes in Penile Firmness With Low-Intensity Shockwave Therapy (LiST)

NCT05756803
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Low-intensity acoustic shockwave therapy
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Great Neck, New York • Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Sep 20, 2026, 1:12 AM EDT