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Conditions: Catheter-Related Infections
Interventions: Ethanol lock, Heparin lock; Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Urinary Tract Infections
Interventions: BLASTX Gel, McKesson Jelly; Device
Lead sponsor: Next Science TM; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Celebration, Florida

Conditions: Catheter-Related Infections
Interventions: (taurolidine and heparin) catheter lock solution, Standard of Care; Drug
Lead sponsor: CorMedix Therapeutics; Industry
Eligibility: Up to 17 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 6
States / cities: Birmingham, Alabama • Phoenix, Arizona • Palo Alto, California + 3 more

Conditions: Catheter Related Infections
Interventions: The Integra External Drainage Catheter., The Ventriclear EVD Antibiotic Catheter, The Codman Bactiseal EVD Catheter Set; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Postoperative Urinary Tract Infection
Interventions: Tamsulosin, Control Group; Drug · Other
Lead sponsor: Emory University; Other
Eligibility: 50 Years and older · Male only
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 4
States / cities: Atlanta, Georgia • Johns Creek, Georgia

Conditions: Hydrocephalus
Interventions: Shunt catheter; Device
Lead sponsor: Codman & Shurtleff; Industry
Eligibility: Not listed
Enrollment: 433 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 2
States / cities: Chicago, Illinois • Hershey, Pennsylvania

Conditions: Nosocomial Infection, Bacteremia, Sepsis, Pneumonia, Urinary Tract Infection, Clostridium Infection
Interventions: 2% chlorhexidine gluconate impregnated cloth, Daily bathing with Bar soap; Drug · Other
Lead sponsor: Cook County Health; Government
Eligibility: 16 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cervical Cancer, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Precancerous/Nonmalignant Condition, Unspecified Adult Solid Tumor, Protocol Specific, Veno-occlusive Disease
Interventions: Fragmin, placebo; Drug · Other
Lead sponsor: Jonsson Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Catheter-Related Infections
Interventions: Ultraviolet light emitting optical fiber; Device
Lead sponsor: Ultraviolet Interventions; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Postoperative Retention of Urine, Postoperative Urinary Tract Infection
Interventions: Not listed
Lead sponsor: Memorial Health System; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Chattanooga, Tennessee

Conditions: Infection Associated With Catheter, Bacteremia, Sepsis
Interventions: Ethanol lock, Heparinized saline; Drug
Lead sponsor: East Carolina University; Other
Eligibility: Up to 32 Weeks
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: Catheter-Related Infections, Pressure Injury
Interventions: Patient Safety Display; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Health Care Associated Infection, Catheter-associated Urinary Tract Infection
Interventions: Clinical decision support; Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 79,369 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 8
States / cities: Bronxville, New York • Brooklyn, New York • Cortlandt Manor, New York + 2 more

Conditions: Catheter-Associated Urinary Tract Infection
Interventions: Nitrofurantoin 100 MG, Placebo Oral Tablet; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older · Female only
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Catheter Related Infections, Short Bowel Syndrome
Interventions: 70% ethanol; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Months and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Urinary Retention, Urinary Tract Infections
Interventions: Tamsulosin, Placebo; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Recurrent UTIs, Catheter-Related Infections
Interventions: Nissle 1917; Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: Not listed
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: End-Stage Renal Disease, Hemodialysis Catheter-associated Infection
Interventions: catheter lock solution consisting of N-acetylcystein, tigecycline and heparin; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 100 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 3
States / cities: Houston, Texas

Conditions: Stroke, Catheter Associated Urinary Tract Infection
Interventions: Nursing protocol to avoid Foley catheter placement; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Infection; Dialysis Catheter
Interventions: NAC/Tigecycline/Heparin combination lock solution, Standard anticoagulant (Heparin or Citrate); Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 70 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: San Diego, California

Conditions: Catheter-related Infections
Interventions: Mino-Lok, Antibiotic lock; Drug
Lead sponsor: Leonard-Meron Biosciences, Inc.; Industry
Eligibility: 12 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 19
States / cities: Washington D.C., District of Columbia • Gainesville, Florida • Hines, Illinois + 16 more

Conditions: Central Line-Associated Bloodstream Infection
Interventions: ethanol, heparin-saline placebo; Drug
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 6 Months to 25 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Catheter; Infection (Indwelling Catheter), Catheter Infection, Catheter-Related Infections, Catheter Bacteraemia, Urinary Tract Infections
Interventions: Povidone-iodine irrigation; Drug
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older · Male only
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Central Line Associated Blood Stream Infections (CLABSI)
Interventions: (taurolidine and heparin) catheter lock solution, Heparin; Drug
Lead sponsor: CorMedix Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 17
States / cities: Los Angeles, California • Washington D.C., District of Columbia • Doral, Florida + 13 more

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Efficacy and Safety of Ethanol Lock Therapy for the Prevention of Central Line-associated Bloodstream Infections

Efficacy of BLASTX in Catheter Associated Bacteriuria Versus Standard of Care (SOC)

Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age

Quality Control: A Prospective Analysis of EVD Effectiveness

Function of Tamsulosin in Older Males Undergoing Surgery With Indwelling Catheter

A Registry for Comparing Catheter-Related Infection Rates Among Various Shunt Systems in the Treatment of Hydrocephalus

Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections

Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter

Treatment of Infected Dialysis Catheters With Fiber Optic Ultraviolet Light

Day Zero Urinary Catheter Removal in Gen Thoracic Surgery Patients

Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates

Pilot Testing a Patient Safety Display in the Hospital Setting

Clinical Decision Support to Reduce Catheter Associated Urinary Tract Infections

Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery

Trial of 70% Ethanol Versus Heparin to Reduce the Rate of Central Line Infections in Children With Short Bowel Syndrome

Prevention of Post-operative Urinary Retention

Novel Probiotic Treatment for Prevention of Recurrent UTIs in Children

A Novel Catheter Lock Solution for Treatment of Tunneled Hemodialysis Catheter-Associated Bacteremia

Pilot Study of Avoidance of Bladder Catheters in Stroke Patients to Avoid Urinary Tract Infections

Use of a Novel Catheter Lock Solution For Treatment of Hemodialysis Catheter Infections

Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI

Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection

Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)