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Showing 1–24 of 142 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intermittent Claudication Clear all
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

ARREST PAD (Peripheral Arterial Disease)

NCT00153166
View directory record Official record
Conditions
Arterial Occlusive Disease, Intermittent Claudication, Insulin Resistance
Interventions
atorvastatin and pioglitazone, atorvastatin/placebo, pioglitazone/placebo, placebo/placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 29, 2014 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy of K-134 for the Treatment of Intermittent Claudication

NCT00783081
View directory record Official record
Conditions
Intermittent Claudication
Interventions
K-134, Cilostazol 100 mg BID, Placebo
Drug
Lead sponsor
Kowa Research Institute, Inc.
Industry
Eligibility
40 Years and older
Enrollment
387 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
30
States / cities
Tucson, Arizona • Little Rock, Arkansas • Beverly Hills, California + 27 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2012 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Phase 4 Interventional Results available

Evaluation of Cilostazol in Combination With L-Carnitine

NCT00822172
View directory record Official record
Conditions
Peripheral Vascular Disease, Intermittent Claudication, Peripheral Arterial Disease
Interventions
Levocarnitine tartrate, cilostazol
Dietary Supplement · Drug
Lead sponsor
Colorado Prevention Center
Other
Eligibility
40 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
24
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Palo Alto, California + 18 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2019 · Synced Jul 19, 2026, 10:38 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Bioequivalence Study of PMR Compared to Cilostazol IR Tablets in Healthy Volunteers

NCT05191862
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Cilostazol 100 mg, PMR 135 mg
Drug
Lead sponsor
Genovate Biotechnology Co., Ltd.,
Industry
Eligibility
18 Years to 45 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Jul 19, 2026, 10:38 AM EDT
Withdrawn Phase 4 Interventional

ATHERO: Advanced Technology Halting Early Re-Stenosis and Occlusion

NCT00407940
View directory record Official record
Conditions
Arterial Occlusive Disease, Intermittent Claudication
Interventions
Lower extremity Atherectomy and Cryoplasty
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Jul 19, 2026, 10:38 AM EDT
Recruiting Phase 3 Interventional

Improving Mobility After Revascularization in Peripheral Artery Disease

NCT06686121
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication, Peripheral Vascular Disease, Mobility Limitation, Revascularization
Interventions
Home Based Exercise, Nitrate Rich Beetroot Juice, Attention Control, Placebo Beetroot Juice Without Nitrate
Behavioral · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
7
States / cities
Tucson, Arizona • Downey, California • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Not applicable Interventional Results available

Effect of HPIPC for the Treatment of Ischemic Ulcers in Subjects With PAD

NCT01420289
View directory record Official record
Conditions
PVD, Arterial Ulcers
Interventions
High pressure intermittent pneumatic compression (HPIPC), Excercise
Device · Behavioral
Lead sponsor
Calvary Hospital, Bronx, NY
Other
Eligibility
18 Years to 90 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2012 · Synced Jul 19, 2026, 10:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Patients With Heart Disease Not Eligible for Research Protocols

NCT00001458
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Up to 99 Years
Enrollment
7,829 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Jul 19, 2026, 10:38 AM EDT
Active, not recruiting Not applicable Interventional Results available

The MOTION Study - Treatment of LSS With the MILD Procedure

NCT03610737
View directory record Official record
Conditions
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions
MILD Procedure, Conventional Medical Management (CMM)
Device · Other
Lead sponsor
Vertos Medical, Inc.
Industry
Eligibility
50 Years to 80 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
18
States / cities
Newport Beach, California • Colorado Springs, Colorado • Lakeland, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Phase 3 Interventional Results available

EPIC Nitinol Stent System in the Treatment of Atherosclerotic Lesions in Iliac Arteries

NCT00896337
View directory record Official record
Conditions
Iliac Artery Stenosis
Interventions
Epic™ Nitinol Stent System, Anti-platelet therapy, Anti-coagulation therapy
Device · Drug
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
28
States / cities
Tucson, Arizona • Brandon, Florida • Fort Lauderdale, Florida + 24 more
Source: ClinicalTrials.gov public record
Updated May 6, 2015 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Phase 1 Interventional

Technical Development of Cardiovascular Magnetic Resonance Imaging

NCT00064896
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
MRI
Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 29, 2017 · Synced Jul 19, 2026, 10:38 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

VascTrac Peripheral Arterial Disease (PAD) Study

NCT03048890
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication
Interventions
Physical activity levels
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Jul 19, 2026, 10:38 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Assessing Superion Clinical Endpoints vs. Decompression

NCT03048955
View directory record Official record
Conditions
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Interventions
Superion® IDS, Direct decompression Surgery
Device · Procedure
Lead sponsor
VertiFlex, Incorporated
Industry
Eligibility
45 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
5
States / cities
Birmingham, Alabama • Carlsbad, California • Celebration, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Comparison of Prosthetic Femoropopliteal Bypass Versus Viabahn Endoprosthesis for Treatment of Symptomatic Femoral Artery Occlusive Disease

NCT00693823
View directory record Official record
Conditions
Atherosclerosis, Lower Extremity Ischemia, Claudication, Rest Pain
Interventions
Femoral-popliteal Bypass, Angioplasty and stent placement with Viabahn covered stent-graft(W.L. Gore & Associates, Flagstff, Arizona) of superficial femoral artery
Procedure · Device
Lead sponsor
Texas Vascular Associates
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2008 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Not applicable Interventional Results available

Absolute Pro® MOMENTUM™

NCT01444378
View directory record Official record
Conditions
Peripheral Artery Disease, Peripheral Vascular Disease
Interventions
Stenting using Absolute Pro® and Pro LL® Peripheral Stent Systems
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Santa Clara, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Jul 19, 2026, 10:38 AM EDT
Not listed Phase 2 Interventional

Treatment of Claudication With a Peristaltic Pulse Pneumatic Device

NCT01007604
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Peristaltic pulse PCD, Exercise and lifestyle counseling
Device · Other
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Nov 3, 2009 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Rehabilitation in Veterans With PAD

NCT02607046
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Exercise training, NMES
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Jul 19, 2026, 10:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Exercise Training on Skeletal Muscle Metabolism in Peripheral Artery Disease (PAD)

NCT01231360
View directory record Official record
Conditions
Claudication
Interventions
Exercise Training, Normal routine
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2013 · Synced Jul 19, 2026, 10:38 AM EDT
Recruiting Not applicable Interventional

Passive Calf Stretching Therapy in Peripheral Artery Disease

NCT06041880
View directory record Official record
Conditions
Peripheral Artery Disease, Claudication, Intermittent
Interventions
Passive calf muscle stretching device
Device
Lead sponsor
Penn State University
Other
Eligibility
40 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

BE Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers

NCT05466734
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Cilostazol Tablet 100 mg, PMR Tablet 135 mg
Drug
Lead sponsor
Genovate Biotechnology Co., Ltd.,
Industry
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Jul 19, 2026, 10:38 AM EDT
Recruiting Not applicable Interventional

Red Light Treatment in Peripheral Artery Disease

NCT03203239
View directory record Official record
Conditions
Peripheral Artery Disease, Claudication, Intermittent, Vasodilation
Interventions
Red Light (670 nm energy), Octafluoropropane
Device · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 19, 2026, 10:38 AM EDT
Terminated Phase 4 Interventional Results available

Cilostazol After Lower Extremity Arterial Revascularization Trial

NCT02374957
View directory record Official record
Conditions
Peripheral Arterial Disease, Claudication (Finding)
Interventions
Cilostazol
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
35 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2018 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Coflex PS3 Actual Conditions for Use Study

NCT02555280
View directory record Official record
Conditions
Spinal Stenosis Lumbar
Interventions
coflex® Interlaminar Technology, Decompression
Device · Procedure
Lead sponsor
Companion Spine, LLC
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
14
States / cities
Phoenix, Arizona • Sacramento, California • San Luis Obispo, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 19, 2026, 10:38 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy of Allogeneic Cells for the Treatment of Intermittent Claudication(IC)

NCT01679990
View directory record Official record
Conditions
Intermittent Claudication, Peripheral Artery Disease
Interventions
PLX-PAD Low dose, PLX-PAD high doses, Double Placebo, high dose +Placebo
Biological
Lead sponsor
Pluristem Ltd.
Industry
Eligibility
45 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
15
States / cities
Birmingham, Alabama • Clearwater, Florida • Gainesville, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Jul 19, 2026, 10:38 AM EDT