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Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.
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Recruiting Phase 2 Interventional Accepts healthy volunteers

Neural Correlates During Alcohol Intoxication

NCT06118580
Conditions
Alcohol Use Disorder, Intermittent Explosive Disorder
Interventions
Alcohol (Ethanol), Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 55 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Anger, Intermittent Explosive Disorder
Interventions
anger management therapy
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Phase 2 Interventional Accepts healthy volunteers

Inflammatory Challenge in Human Aggression.

NCT06665074
Conditions
Intermittent Explosive Disorder
Interventions
Endotoxin (E. coli O:113, Reference Endotoxin), Saline (Placebo)
Biological · Other
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 55 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Anger, Intermittent Explosive Disorder
Interventions
Cognitive Behavioral Therapy, Supportive Psychotherapy
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Not listed Not applicable Interventional Accepts healthy volunteers

Maladaptive Anger Treatment

NCT06275607
Conditions
Anger, Intermittent Explosive Disorder, Emotional Distress, Aggression, Violence
Interventions
Cognitive Behavioral Affective Therapy, Emotional Discussion
Behavioral
Lead sponsor
The University of Texas at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Intermittent Explosive Disorder
Interventions
SRX246, Placebo
Drug
Lead sponsor
Azevan Pharmaceuticals
Industry
Eligibility
21 Years to 55 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
7
States / cities
Atlanta, Georgia • Chicago, Illinois • O'Fallon, Missouri + 4 more
Recruiting Phase 2 Interventional Accepts healthy volunteers

Effect of Nitrous Oxide on Aggression.

NCT06118567
Conditions
Intermittent Explosive Disorder
Interventions
Nitrous oxide, Room Air
Drug
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Intermittent Explosive Disorder, Childhood Aggression, Oppositional Defiant Disorder, Attention Deficit Disorder
Interventions
Parent Management Training, Placebo, Intuniv
Behavioral · Other · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
6 Years to 12 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Intermittent Explosive Disorder
Interventions
Cognitive Bias Modification, Cognitive Bias Control
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Intermittent Explosive Disorder
Interventions
AVP-786, Placebo
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
9
States / cities
Gainesville, Florida • Atlanta, Georgia • Chicago, Illinois + 6 more
Conditions
Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit/Hyperactivity Disorder (ADHD), Intermittent Explosive Disorder, Impulse-Control Disorders, Adjustment Disorder, Bipolar Disorder, Pervasive Developmental Disorder
Interventions
Risperdal
Drug
Lead sponsor
Ohio State University
Other
Eligibility
4 Years to 14 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2005
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting Phase 2 Interventional Accepts healthy volunteers

Pimavanserin and Aggression and Social Cognition.

NCT05895513
Conditions
Intermittent Explosive Disorder
Interventions
Pimavanserin 34 mg, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Intermittent Explosive Disorder
Interventions
Fluoxetine, Divalproex, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Chicago, Illinois