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ClinicalTrials.gov public records Last synced May 21, 2026, 6:19 PM EDT

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Showing 1–4 of 4 matching trials from the live ClinicalTrials.gov search.

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Filters: Condition: Intra - and Extrahepatic Cholangiocarcinoma Clear all

Recruiting Phase 2 Interventional

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

NCT07282912

View directory record Official record

Conditions: Foregut Adenocarcinoma, Esophageal Adenocarcinoma, Gastroesophageal Adenocarcinoma, Gastric Adenocarcinoma, Pancreas Adenocarcinoma, Duodenal Adenocarcinoma, Ampullary Adenocarcinoma, Gallbladder Adenocarcinoma, Intra - and Extrahepatic Cholangiocarcinoma
Interventions: Sequential cytoreductive intervention, Signatera Genome ultra-sensitive ctDNA blood test; Procedure · Diagnostic Test
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 80 Years

Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New Haven, Connecticut

Source: ClinicalTrials.gov public record

Updated Mar 3, 2026 · Synced May 21, 2026, 6:19 PM EDT

Terminated Phase 2 Interventional Results available

Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers

NCT00832637

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Conditions: Hepatocellular Carcinoma, Cholangiocellular Carcinoma, Cholangiocarcinoma of the Extrahepatic Bile Duct, Bile Duct Cancer, Periampullary Adenocarcinoma, Gallbladder Cancer, Extrahepatic Bile Duct Cancer
Interventions: Cisplatin, Erlotinib, Gemcitabine; Drug
Lead sponsor: New Mexico Cancer Research Alliance; Other
Eligibility: 18 Years and older

Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2017
U.S. locations: 2
States / cities: San Francisco, California • Albuquerque, New Mexico

Source: ClinicalTrials.gov public record

Updated Jun 28, 2018 · Synced May 21, 2026, 6:19 PM EDT

Terminated Phase 2 Interventional Results available

Chemoradiation +Gemcitabine +Continuous 5-FU (Fluorouracil) Followed by High Dose Brachytherapy/Stereotactic Radiation Boost in Locally Advanced Intra/Extrahepatic Cholangiocarcinoma

NCT00983541

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Conditions: Cancer
Interventions: Fluorouracil (5-FU), Brachytherapy or SBRT (Stereotactic body radiation therapy), Gemcitabine; Drug · Radiation
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older

Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Salt Lake City, Utah

Source: ClinicalTrials.gov public record

Updated Aug 18, 2015 · Synced May 21, 2026, 6:19 PM EDT

Completed Phase 2 Interventional

A Study of ABC294640 Alone and in Combination With HCQ Sulfate in the Treatment of Advanced Cholangiocarcinoma

NCT03377179

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Conditions: Cholangiocarcinoma, Cholangiocarcinoma Non-resectable, Cholangiocarcinoma, Perihilar, Cholangiocarcinoma, Extrahepatic, Cholangiocarcinoma, Intrahepatic
Interventions: ABC294640, Hydroxychloroquine Sulfate 200 MG; Drug
Lead sponsor: RedHill Biopharma Limited; Industry
Eligibility: 18 Years and older

Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 5
States / cities: Phoenix, Arizona • Atlanta, Georgia • Rochester, Minnesota + 2 more

Source: ClinicalTrials.gov public record

Updated Jul 22, 2025 · Synced May 21, 2026, 6:19 PM EDT