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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intubation Complication Clear all
Completed Not applicable Interventional Accepts healthy volunteers

ConsCIOUS2 Study of the Isolated Forearm Technique Commands

NCT03503357
View directory record Official record
Conditions
Anesthesia Awareness
Interventions
IFT Testing1, IFT Testing 2, IFT Testing 3, IFT Testing 4
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
344 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
3
States / cities
New York, New York • Philadelphia, Pennsylvania • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Not applicable Interventional

Nasotracheal Intubation With VL vs DL in Infants Trial

NCT05433155
View directory record Official record
Conditions
Intubation Complication, Intubation; Difficult or Failed, Hypoxia, Hypoxemia, Anesthesia Intubation Complication, Pediatric HD
Interventions
Nasotracheal intubation
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Day to 365 Days
Enrollment
680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Aurora, Colorado • Washington D.C., District of Columbia • Philadelphia, Pennsylvania + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Jul 21, 2026, 11:23 AM EDT
Recruiting Not applicable Interventional

The ED-AWARENESS-2 Trial

NCT05534243
View directory record Official record
Conditions
Awareness, Mechanical Ventilation, Intubation Complication, PTSD
Interventions
Standard neuromuscular blocker practices, Education
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
3,090 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Iowa City, Iowa • Minneapolis, Minnesota • Camden, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jul 21, 2026, 11:23 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Incidence of Acute Laryngeal Injury Following Endotracheal Intubation

NCT03250975
View directory record Official record
Conditions
Intubation Complication
Interventions
Budesonide and Azithromycin, Placebo control of budesonide and azithromycin
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 21, 2026, 11:23 AM EDT
Recruiting Phase 3 Interventional

InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS

NCT05960929
View directory record Official record
Conditions
Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
Interventions
Infasurf Aero™
Combination Product
Lead sponsor
ONY
Industry
Eligibility
29 Weeks to 36 Weeks
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
10
States / cities
Phoenix, Arizona • San Diego, California • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2025 · Synced Jul 21, 2026, 11:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Expert Consensus Statements for the Management of a Physiologically Difficult Airway Using the Delphi Method (PDADelphi)

NCT05762068
View directory record Official record
Conditions
Intubation; Difficult or Failed, Intubation Complication, Hemodynamic Instability, Critical Illness
Interventions
Delphi procedure
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Not applicable Interventional

Apneic Oxygenation in the Pediatric Intensive Care Unit

NCT03374046
View directory record Official record
Conditions
Intubation Complication
Interventions
Apneic Oxygenation
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
0 Days to 17 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Phase 4 Interventional Results available

Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation

NCT03026777
View directory record Official record
Conditions
Acute Respiratory Failure, Intubation Complication
Interventions
intravenous crystalloid fluid, 500 mL
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
337 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
7
States / cities
Birmingham, Alabama • Jefferson, Louisiana • New Orleans, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Jul 21, 2026, 11:23 AM EDT
Recruiting No phase listed Observational

Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients

NCT07222007
View directory record Official record
Conditions
Critically Ill, Intubation Complication, Oxygenation, Airway Management, Propofol, Ketamine
Interventions
induction type for intubation in ICU
Procedure
Lead sponsor
Zeliha Alicikus
Government
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comprehensive Preoperative Airway Grading

NCT04864106
View directory record Official record
Conditions
Anesthesia Intubation Complication
Interventions
Endoscopic Examination
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Phase 3 Interventional Results available

Surfactant Positive Airway Pressure and Pulse Oximetry Trial

NCT00233324
View directory record Official record
Conditions
Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age, Premature Birth, Bronchopulmonary Dysplasia, Retinopathy of Prematurity
Interventions
Surfactant, Continuous Positive Airway Pressure (CPAP), Supplemental oxygen with target saturation of 85 to 89%, Supplemental oxygen with target saturation of 91 to 95%
Drug · Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
24 Weeks to 27 Weeks
Enrollment
1,316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2016
U.S. locations
22
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Jul 21, 2026, 11:23 AM EDT
Terminated Phase 4 Interventional Results available

Evaluation of Above the Cuff Suctioning During General Anesthesia

NCT01386879
View directory record Official record
Conditions
Secretion Removal Above ETT Cuff
Interventions
methylene blue
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 7, 2022 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Phase 2 Interventional Results available

Strategies To Prevent Pneumonia 2 (SToPP2)

NCT00893763
View directory record Official record
Conditions
Infections, Hospital, Ventilator-Associated Pneumonia, Mechanical Ventilation Complication
Interventions
Pre-intubation CHX, Control
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 10, 2016 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Phase 4 Interventional

Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation

NCT03787732
View directory record Official record
Conditions
Acute Respiratory Failure, Intubation Complication, Hypotension on Induction
Interventions
Fluid Bolus, No Fluid Bolus
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,067 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
11
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Burlington, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2021 · Synced Jul 21, 2026, 11:23 AM EDT
Completed No phase listed Observational

The PAWS-COVID-19 (Pediatric AirWay complicationS COVID-19) Registry

NCT04449042
View directory record Official record
Conditions
Airway Management, COVID19
Interventions
airway management during sedation or general anesthesia
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
14,835 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Jul 21, 2026, 11:23 AM EDT
Completed No phase listed Observational

Post-extubation Assessment of Laryngeal Symptoms and Severity

NCT03726086
View directory record Official record
Conditions
Intubation, Intratracheal, Critical Illness, Mechanical Ventilation Complication, Complication of Ventilation Therapy
Interventions
laryngoscopy
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Jul 21, 2026, 11:23 AM EDT
Completed No phase listed Observational

Delivery Room Practice Change Following the Initiation of the NICHD SUPPORT Trial

NCT01601886
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
Luc Brion
Other
Eligibility
24 Weeks to 35 Weeks
Enrollment
3,843 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 17, 2012 · Synced Jul 21, 2026, 11:23 AM EDT
Recruiting Not applicable Interventional

Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study

NCT06085326
View directory record Official record
Conditions
Intubation Complication
Interventions
Smart Checklist
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 19 Years
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
6
States / cities
Little Rock, Arkansas • Atlanta, Georgia • Omaha, Nebraska + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jul 21, 2026, 11:23 AM EDT
Terminated Not applicable Interventional Results available

Novel Airway Device to Aid Endotracheal Intubations

NCT03340207
View directory record Official record
Conditions
Intubation Complication, Intubation;Difficult
Interventions
Pneumaglide
Device
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Jul 21, 2026, 11:23 AM EDT
Recruiting Not applicable Interventional

Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

NCT03901924
View directory record Official record
Conditions
Mechanical Ventilation Complication
Interventions
Volume Support Mode Mechanical Ventilation, Assist Control Mode Mechanical Ventilation
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Not applicable Interventional

Utilization of Airway Stabilizing Rod

NCT05899868
View directory record Official record
Conditions
Airway Complication of Anesthesia
Interventions
Time to Intubation using FASTER device
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
5 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Not applicable Interventional Results available

Tracheal Intubation Coaching in NICUs

NCT03194503
View directory record Official record
Conditions
Failed or Difficult Intubation, Sequela, Intubation;Difficult, Intubation Complication
Interventions
VL Coaching training using C-MAC video laryngoscope
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
22 Years to 70 Years
Enrollment
1,512 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
8
States / cities
La Jolla, California • Aurora, Colorado • New Haven, Connecticut + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Jul 21, 2026, 11:23 AM EDT
Completed Phase 4 Interventional Results available

Ketamine Versus Etomidate for Rapid Sequence Intubation

NCT01823328
View directory record Official record
Conditions
Airway Control, Anesthesia, Intubation, Complication
Interventions
Ketamine, Etomidate
Drug
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Jul 21, 2026, 11:23 AM EDT
Withdrawn Not applicable Interventional

Effect of Applying Cuff Air Leak Pressure as Intraoperative Cuff Pressure on Postoperative Complications

NCT04302142
View directory record Official record
Conditions
Intubation Complication
Interventions
ventilation with critical intracuff pressure (Pcr)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Jul 21, 2026, 11:23 AM EDT