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ClinicalTrials.gov public records Last synced May 22, 2026, 3:02 AM EDT

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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Irritability Associated With Autism Spectrum Disorder Clear all
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder (ASD)
Interventions
Brexpiprazole, Placebo
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
5 Years to 17 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced May 22, 2026, 3:02 AM EDT
Terminated Phase 2Phase 3 Interventional Results available
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
Pimavanserin
Drug
Lead sponsor
ACADIA Pharmaceuticals Inc.
Industry
Eligibility
5 Years to 18 Years
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
18
States / cities
Phoenix, Arizona • Glendale, California • San Rafael, California + 15 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced May 22, 2026, 3:02 AM EDT
Completed Phase 2Phase 3 Interventional Results available
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
Pimavanserin, Placebo
Drug
Lead sponsor
ACADIA Pharmaceuticals Inc.
Industry
Eligibility
5 Years to 17 Years
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
18
States / cities
Phoenix, Arizona • Glendale, California • San Rafael, California + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced May 22, 2026, 3:02 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Autism
Interventions
Lurasidone 20 mg daily, Lurasidone, Placebo
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
41
States / cities
Dothan, Alabama • Phoenix, Arizona • Newport Beach, California + 38 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced May 22, 2026, 3:02 AM EDT
Withdrawn Phase 2 Interventional
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder, Autism Spectrum Disorder, ASD
Interventions
JZP541, Placebo
Drug · Other
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced May 22, 2026, 3:02 AM EDT
Recruiting Phase 3 Interventional
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
Lumateperone high dose, Lumateperone low dose, Placebo
Drug
Lead sponsor
Intra-Cellular Therapies, Inc.
Industry
Eligibility
5 Years to 17 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
39
States / cities
Little Rock, Arkansas • Imperial, California • Sacramento, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced May 22, 2026, 3:02 AM EDT
Completed Phase 1 Interventional Results available
View directory record Official record
Conditions
Autism Spectrum Disorder, Aggression, Irritability
Interventions
Transdermal nicotine, Transdermal placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced May 22, 2026, 3:02 AM EDT
Recruiting Phase 3 Interventional
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
Lumateperone high dose, Lumateperone low dose, Placebo
Drug
Lead sponsor
Intra-Cellular Therapies, Inc.
Industry
Eligibility
5 Years to 17 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
37
States / cities
Dothan, Alabama • Peoria, Arizona • Phoenix, Arizona + 31 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced May 22, 2026, 3:02 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
Brexpiprazole
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
5 Years to 17 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
28
States / cities
Dothan, Alabama • Phoenix, Arizona • San Francisco, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced May 22, 2026, 3:02 AM EDT
Not yet recruiting Phase 3 Interventional
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
KarXT, KarX-EC, KarXT + KarX-EC Matching Placebo
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
5 Years to 17 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
19
States / cities
Phoenix, Arizona • Bentonville, Arkansas • Glendale, California + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced May 22, 2026, 3:02 AM EDT
Not yet recruiting Phase 3 Interventional
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
KarXT, KarX-EC, KarXT + KarX-EC Matching Placebo
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
5 Years to 17 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
27
States / cities
Dothan, Alabama • Phoenix, Arizona • Anaheim, California + 23 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced May 22, 2026, 3:02 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Autistic Disorder
Interventions
Aripiprazole, Placebo, D-cycloserine
Drug
Lead sponsor
Indiana University
Other
Eligibility
5 Years to 17 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced May 22, 2026, 3:02 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD)
Interventions
AB-2004, Placebo
Drug
Lead sponsor
Vertero Therapeutics
Industry
Eligibility
5 Years to 17 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
18
States / cities
Dothan, Alabama • Phoenix, Arizona • Tucson, Arizona + 15 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced May 22, 2026, 3:02 AM EDT
Recruiting Phase 3 Interventional
View directory record Official record
Conditions
Schizophrenia, Autism-Related Irritability
Interventions
KarXT
Drug
Lead sponsor
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Industry
Eligibility
5 Years to 17 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
19
States / cities
Anaheim, California • Chino, California • Culver City, California + 16 more
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced May 22, 2026, 3:02 AM EDT