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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
Completed Phase 3 Interventional Accepts healthy volunteers

Improving Health Outcomes for New Mothers and Babies

NCT00360204
Conditions
Hyperbilirubinemia, Jaundice, Dehydration, Postpartum Depression
Interventions
Home Nurse Visit
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
1 Day to 7 Months
Enrollment
1,154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
2
States / cities
Hershey, Pennsylvania
Conditions
Alcoholic Hepatitis (AH)
Interventions
Selonsertib, Prednisolone, Placebo
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 70 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
11
States / cities
Little Rock, Arkansas • Coronado, California • Los Angeles, California + 8 more
Completed No phase listed Interventional Accepts healthy volunteers Results available

BiliCam Clinical Validation Study

NCT03246503
Conditions
Newborn Jaundice
Interventions
BiliCam estimated bilirubin (BCB)
Device
Lead sponsor
BiliCam, LLC
Industry
Eligibility
0 Hours to 191 Hours
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Neonatal Jaundice
Interventions
Picterus Jaundice Pro (JP)
Device
Lead sponsor
Picterus AS
Industry
Eligibility
12 Hours to 192 Hours
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Neonatal Jaundice
Interventions
Picterus Jaundice Pro (JP)
Device
Lead sponsor
Picterus AS
Industry
Eligibility
1 Day to 14 Days
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal
Interventions
BiliSpec
Diagnostic Test
Lead sponsor
William Marsh Rice University
Other
Eligibility
0 Days to 28 Days
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Houston, Texas
Conditions
Hyperbilirubinemia, Neonatal
Interventions
Neolight Phototherapy Mattress, Standard-of-Care
Device
Lead sponsor
Stanford University
Other
Eligibility
28 Weeks to 8 Months
Enrollment
41 participants
Timeline
2018 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders, Gallstones, Obstructive Jaundice, Pancreatic Disorders (Noncancerous), Colorectal Cancer, Esophageal Cancer, Barrett's Esophagus, Gastric Malignancies, Pancreatic Cancer, Pediatric Gastroenterology, Cholangiocarcinoma, Pancreatic Pseudocysts, Acute and Chronic Pancreatitis, Recurrent Pancreatitis, Cholangitis, Bile Leak, Biliary Strictures, Pancreatic Divisum, Biliary and Pancreatic Stones, Choledocholithiasis
Interventions
Interventional Endoscopy
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
12,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Hyperbilirubinemia, Jaundice
Interventions
Gene mutation sample
Procedure
Lead sponsor
Pediatrix
Other
Eligibility
Up to 6 Days
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Greenville, South Carolina
Completed Not applicable Interventional Results available

Malignant Obstruction ZILVER Against Routine Therapy (MOZART I)

NCT00196105
Conditions
Biliary Tract Neoplasms, Pancreatic Neoplasms, Jaundice, Obstructive
Interventions
6 mm Nitinol Zilver Stent, 10 mm Nitinol Zilver Stent, 10 mm Stainless Steel Wallstent
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
21 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Portland, Maine
Conditions
Jaundice, Neonatal, Hyperbilirubinemia, Neonatal
Interventions
Phototherapy, Stannsoporfin, Placebo
Procedure · Drug
Lead sponsor
InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Industry
Eligibility
1 Hour to 72 Hours
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
18
States / cities
Colton, California • San Diego, California • San Francisco, California + 14 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Glycerin Suppositories to Reduce Jaundice in Premature Infants

NCT01746511
Conditions
Idiopathic Hyperbilirubinemia, Neonatal Hyperbilirubinemia, Prematurity
Interventions
Phototherapy, glycerin suppository
Procedure · Drug
Lead sponsor
University of Rochester
Other
Eligibility
30 Weeks to 35 Weeks
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rochester, New York
Conditions
ABO Incompatibility, Hemolytic Disease of Newborn, Neonatal Jaundice, Neonatal Hyperbilirubinemia
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
Up to 28 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Syracuse, New York
Completed No phase listed Observational

Ceftriaxone and Jaundice in Neonates

NCT03133637
Conditions
Jaundice and Sepsis in Neonates
Interventions
ceftriaxone
Drug
Lead sponsor
University of Rochester
Other
Eligibility
3 Days to 7 Days
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, New York
Conditions
Jaundice, Jaundice, Neonatal
Interventions
Ring Phototherapy
Device
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 7 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Aggressive Phototherapy 501-750g, Aggressive Phototherapy 751-1000g, Conservative Phototherapy 501-750g, Conservative Phototherapy 751-1000g
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
12 Hours to 36 Hours
Enrollment
1,974 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more
Completed No phase listed Observational Accepts healthy volunteers

Bilistick Point-of-care System 2.0 Bilirubin Validation

NCT06058910
Conditions
Neonatal Screening, Kernicterus, Newborn Jaundice, Point-of-Care Testing
Interventions
Bilistick System 2.0 point-of-care testing device
Diagnostic Test
Lead sponsor
Kettering Health Network
Other
Eligibility
Up to 2 Weeks
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Kettering, Ohio
Conditions
Pancreaticobiliary Cancers, Jaundice, Bile Duct Obstruction
Interventions
ERCP, EUS FNA
Procedure
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Francisco, California
Completed No phase listed Observational Accepts healthy volunteers

Point-of-Care System for Determination of Bilirubin Capacity in Neonates

NCT02612207
Conditions
Jaundice, Neonatal, Hyperbilirubinemia, Bilirubin-Induced Neurological Dysfunction (BIND)
Interventions
Bilirubin Binding Capacity by Hematofluorometry Validation
Device
Lead sponsor
Stanford University
Other
Eligibility
6 Hours to 14 Days
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Stanford, California • Lakewood, New Jersey
Not listed Not applicable Interventional

EUS BD vs ERCP TP for Pancreatic Cancer

NCT03063554
Conditions
Pancreatic Cancer, Pancreatic Adenocarcinoma, Biliary Tract Neoplasms, Biliary Duct Obstruction, Unresectable Pancreatic Cancer, Periampullary Cancer, Periampullary Carcinoma Non-Resectable
Interventions
Endoscopic Ultrasound Guided Biliary Drainage, ERCP
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

SMOFlipid to Lessen the Severity of Neonatal Cholestasis

NCT02721277
Conditions
Cholestasis, Jaundice, Obstructive
Interventions
SMOFlipid
Drug
Lead sponsor
University of Florida
Other
Eligibility
23 Weeks to 1 Year
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Nutritional and Metabolic Diseases
Interventions
stannsoporfin, Sham Injection
Drug · Other
Lead sponsor
InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Industry
Eligibility
12 Hours to 36 Hours
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Neonatal Jaundice
Interventions
Assessment of unbound bilirubin levels
Other
Lead sponsor
Rutgers University
Other
Eligibility
6 Hours to 7 Days
Enrollment
180 participants
Timeline
2017 – 2019
U.S. locations
1
States / cities
New Brunswick, New Jersey
Conditions
Obstructive Jaundice, Pancreatic Cancer
Interventions
Stent Dysfunction, Complications
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Orlando, Florida