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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Knee Arthroscopy Clear all
Completed Not applicable Interventional

Neuromuscular Consequences of Knee Arthroscopy

NCT01786772
View directory record Official record
Conditions
Tear of Fibrocartilage of Joint
Interventions
Cryotherapy and compression, Cryotherapy
Other
Lead sponsor
Creighton University
Other
Eligibility
15 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 25, 2018 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated No phase listed Observational

Web Based Orthopaedic Sports Medicine Registry

NCT01191151
View directory record Official record
Conditions
Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow, Degenerative and Traumatic Pathology of the Foot and Ankle, Degenerative and Traumatic Pathology of the Hand and Wrist, Degenerative and Traumatic Pathology of the Hip
Interventions
Not listed
Lead sponsor
Arthrex, Inc.
Industry
Eligibility
12 Years and older
Enrollment
12,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
220
States / cities
Birmingham, Alabama • Montgomery, Alabama • Anchorage, Alaska + 171 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Opioid Consumption After Knee Arthroscopy

NCT03299920
View directory record Official record
Conditions
Surgical Procedure, Unspecified, Orthopedic Disorder
Interventions
Standardized instructions, Conventional instructions
Other
Lead sponsor
Giorgio Veneziano
Other
Eligibility
Up to 20 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated No phase listed Observational Results available

SCP® Observational Study of the Knee

NCT03110224
View directory record Official record
Conditions
Bone Marrow Edema
Interventions
Subchondroplasty Procedure with AccuFill
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
14
States / cities
Parker, Colorado • Palm Beach Gardens, Florida • Tampa, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated Phase 2 Interventional Results available

Chloroprocaine Spinal for Outpatient Knee Surgery

NCT03365752
View directory record Official record
Conditions
Knee Arthroscopy
Interventions
Chloroprocaine, Mepivacaine, General Anesthetics
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Find Optimal Dose of Local Spinal Anesthetic (Mepivacaine) Combined With Narcotic (Fentanyl) For Knee Surgery

NCT01701102
View directory record Official record
Conditions
Arthroscopic Knee Surgery
Interventions
Mepivacaine (24 mg) plus fentanyl, Mepivacaine (27 mg) plus fentanyl, Mepivacaine (30 mg) plus fentanyl, Mepivacaine
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated Phase 4 Interventional Results available

Lipogems Prospective Study

NCT03922490
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Lipogems Device PLUS debridement, Debridement only
Device · Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 70 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jul 20, 2026, 6:42 PM EDT
Completed No phase listed Observational

Post Market Study of DeNovo NT, Natural Tissue Graft

NCT00791245
View directory record Official record
Conditions
Cartilage Repair
Interventions
Particulated Juvenile Cartilage Allograft
Biological
Lead sponsor
Zimmer Orthobiologics, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
3
States / cities
Chicago, Illinois • Indianapolis, Indiana • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 10, 2014 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated No phase listed Observational

Journey II BCS CMS Total Knee System Compared to Other PS Total Knee Systems in PT Setting

NCT02820766
View directory record Official record
Conditions
Osteoarthritis, Degenerative Arthritis, Traumatic Arthritis
Interventions
Not listed
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
21 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Annapolis, Maryland • Eugene, Oregon • State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2017 · Synced Jul 20, 2026, 6:42 PM EDT
Recruiting Phase 2 Interventional

Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery

NCT07020312
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Hip Arthroscopy
Interventions
Visualization training with neurofeedback, Standard post-surgical rehabilitation therapy
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Active, not recruiting Not applicable Interventional

Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation

NCT05735236
View directory record Official record
Conditions
ACL Tear
Interventions
BFR Cuff
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
16 Years to 60 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Centennial, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated Not applicable Interventional

Blood Flow Restriction Training in Rehabilitation Patients

NCT02174770
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
Interventions
Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Phase 2 Interventional Results available

Early Neuromuscular Electrical Stimulation For Quadriceps Muscle Activation Deficits Following Total Knee Replacement

NCT00800254
View directory record Official record
Conditions
Osteoarthritis
Interventions
Neuromuscular Electrical Stimulation (NMES), Standard Rehabilitation Protocol
Device · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional Results available

Study of Suture Repair of Torn Meniscus in the Knee

NCT02237001
View directory record Official record
Conditions
Meniscal Tear, Meniscus Tear
Interventions
Suture-based meniscal repair
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
8
States / cities
Encinitas, California • Long Beach, California • Gulf Breeze, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Traditional PT v Internet Based PT After Total Knee Arthroscopy

NCT04843280
View directory record Official record
Conditions
Physical Therapy
Interventions
FORCE therapeutics (physical therapy), Traditional Outpatient Physical Therapy
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Phase 4 Interventional

Tranexamic Acid for Total Knee Arthroscopy

NCT04443920
View directory record Official record
Conditions
Blood Loss, Surgical
Interventions
Tranexamic acid (TXA), Placebo Normal Saline (NS)
Drug
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional Results available

Opiates Prescribing for Knee Arthroscopies and ACL Reconstruction

NCT03876743
View directory record Official record
Conditions
Knee Injuries, ACL Injury
Interventions
Group 1-Knee Arthroscopy, Group 2-Knee Arthroscopy, Group 1-ACL reconstruction, Group 2-ACL reconstruction
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Investigating the Efficacy of Osteopathic Manipulative Treatment on Gait Dysfunction Following Knee Surgery

NCT05580640
View directory record Official record
Conditions
Knee Arthroscopy, Knee Arthroplasty, Osteopathic Manipulative Treatment, Gait, Unsteady
Interventions
OMT
Procedure
Lead sponsor
Midwestern University
Other
Eligibility
21 Years to 90 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated Not applicable Interventional Results available

Controlled Trial to Compare Single Versus Two Portal Knee Arthroscopy Techniques

NCT02648971
View directory record Official record
Conditions
Injuries, Knee
Interventions
Single Portal Knee Arthroscopy, Two Portal Knee Arthroscopy
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 29, 2020 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control

NCT01279447
View directory record Official record
Conditions
Internal Derangement of Knee
Interventions
0.25% Bupivacaine, Normal Saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2014 · Synced Jul 20, 2026, 6:42 PM EDT
Not listed Not applicable Interventional

Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects

NCT02090140
View directory record Official record
Conditions
Degenerative Lesion of Articular Cartilage of Knee
Interventions
ADSC Application, Microfracture
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
3
States / cities
Redwood City, California • Santa Monica, California • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Jul 20, 2026, 6:42 PM EDT
Active, not recruiting Phase 3 Interventional

Dronabinol After Arthroscopic Surgery

NCT05335252
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee, Knee Ligament Injury, Chondral Injury of Left Knee, Chondral Injury of Right Knee, Loose Body Knee
Interventions
Dronabinol, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional Results available

Subchondroplasty® Knee RCT

NCT03112200
View directory record Official record
Conditions
Bone Marrow Edema, Knee Pain Chronic, Knee Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis
Interventions
Subchondroplasty with Arthroscopy, Arthroscopy Alone
Procedure
Lead sponsor
Zimmer Biomet
Industry
Eligibility
30 Years to 75 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
12
States / cities
Encinitas, California • Loma Linda, California • Stanford, California + 9 more
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Withdrawn Not applicable Interventional

Dynamic Contrast-Enhanced Fluorescence Arthroscopy of Meniscus Pilot

NCT05072717
View directory record Official record
Conditions
Knee Injuries
Interventions
Perfusion with Indocyanine green
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Jul 20, 2026, 6:42 PM EDT