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ClinicalTrials.gov public records Last synced May 21, 2026, 11:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions
Exercise Group
Other
Lead sponsor
Johanna M. Hoch
Other
Eligibility
18 Years to 35 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 3, 2020 · Synced May 21, 2026, 11:51 PM EDT
Conditions
ACL Tears
Interventions
MRI
Diagnostic Test
Lead sponsor
Skye Biologics Holdings, LLC
Industry
Eligibility
14 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture, Patella Fracture, Tibial Shaft Fracture with or Without Associated Fibula Fracture, Ankle Fracture (bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Tibial Pilon Fracture, Talar Head, Neck, Body, or Process Fractures, Calcaneus Fractures, Lisfranc Injuries, Isolated or Multiple Metatarsal Fractures, Phalanx Fractures of the Foot, Single or Multiple, Clavicle Fractures, Proximal Humerus Fractures, Humeral Shaft Fractures, Distal Humerus Fractures (intra or Extra-articular), Olecranon Fractures, Radial Head or Neck Fractures, Elbow Fractures Involving a Combination of Fractures of the Radius and Uln, Forearm Fractures (both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft), Distal Radius Fractures
Interventions
Opioid-free pain treatment
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2024 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries
Interventions
Self-guided pre-habilitation exercise program, Traditional pre-habilitation
Other
Lead sponsor
WellSpan Health
Other
Eligibility
13 Years to 50 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 26, 2023 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
Interventions
Medial Patellofemoral Ligament (MPFL) Reconstruction
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
10 Years to 35 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
16
States / cities
Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Interventions
Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine, Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml.
Procedure · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced May 21, 2026, 11:51 PM EDT
Conditions
ACL Injury
Interventions
Arthrex Internal Brace, ACL Reconstruction
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced May 21, 2026, 11:51 PM EDT
Conditions
ACL Tear
Interventions
NMES and BFR, Standard physical therapy
Other
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sunnyvale, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Anterior Cruciate Ligament Injuries
Interventions
post-surgical functional bracing
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
14 Years to 39 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced May 21, 2026, 11:51 PM EDT
Conditions
ACL Injury
Interventions
OOC
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Tibial Shaft Fracture, Tibial Plateau Fracture
Interventions
Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Knee Injury
Interventions
CR Plug
Other
Lead sponsor
RTI Surgical
Industry
Eligibility
18 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
4
States / cities
Birmingham, Alabama • Phoenix, Arizona • Englewood, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury, Defect of Articular Cartilage
Interventions
Neocartilage Implant/DeNovo® ET (Engineered Tissue Graft), Microfracture
Biological · Other
Lead sponsor
ISTO Technologies, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
9
States / cities
Los Angeles, California • Santa Monica, California • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers
Conditions
Knee Injuries, Knee Osteoarthritis
Interventions
Knee Joint Effusion
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced May 21, 2026, 11:51 PM EDT
Conditions
ACL - Anterior Cruciate Ligament Rupture
Interventions
Biocomposite intereference screw femoral tunnel fixation, Endobutton (Tightrope) femoral tunnel fixation
Device
Lead sponsor
Kelsey-Seybold Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Rupture of Anterior Cruciate Ligament
Interventions
Somatropin, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 5, 2020 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
Interventions
Joint Manipulation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
Conditions
ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture, Anesthesia
Interventions
Acupuncture + Standard of Care
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
12 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional
Conditions
Anterior Cruciate Ligament Injuries, Opioid Use
Interventions
ACL Opioid Exposure Reduction Program
Behavioral
Lead sponsor
Karen Derefinko, PhD
Other
Eligibility
12 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Knee Injuries, Cartilage Injury, Cartilage Disease, Knee Discomfort
Interventions
Microfracture, Microfracture plus placement of Chondro-Gide® ACC
Procedure · Device
Lead sponsor
Geistlich Pharma AG
Industry
Eligibility
18 Years to 55 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Phoenix, Arizona • Stamford, Connecticut • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Anterior Cruciate Ligament Injury, ACL Injury, ACL - Anterior Cruciate Ligament Rupture
Interventions
Femoral Nerve Block, Adductor Nerve Block, No Block
Procedure · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 9, 2018 · Synced May 21, 2026, 11:51 PM EDT
Conditions
Hand Injuries, Wrist Injuries, Ligament Injury, Ligament Rupture, Ligament Avulsion
Interventions
Ligament Reconstruction with Allograft Ligament
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced May 21, 2026, 11:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available
Conditions
Injury Leg
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 55 Years
Enrollment
1,891 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced May 21, 2026, 11:51 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
Conditions
Knee Osteoarthritis
Interventions
BEST™ HVPC microcurrent electrical stimulation Pro-Sport Ultra® device
Device
Lead sponsor
Avazzia, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced May 21, 2026, 11:51 PM EDT