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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Kyphoplasty Clear all
Completed No phase listed Observational

Evaluation of Outcomes of DFine StabiliT Kyphoplasty in Vertebral Compression Fractures Due to Osteoporosis

NCT01839682
View directory record Official record
Conditions
Osteoporosis, Vertebral Fracture
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
50 Years to 90 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2013 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Phase 1Phase 2 Interventional

Effect of Samarium on the Relief of Pain Due to Vertebral Metastases

NCT00374751
View directory record Official record
Conditions
Cancer, Metastasis, Pain
Interventions
Samarium (153SM)
Drug
Lead sponsor
New York Presbyterian Brooklyn Methodist Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Phase 3 Interventional

Cost Effectiveness and Efficacy of Kyphoplasty and Vertebroplasty Trial

NCT00279877
View directory record Official record
Conditions
Osteoporotic Vertebral Compression Fractures
Interventions
Kyphoplasty
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
50 Years to 100 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Phase 4 Interventional Results available

Medtronic SCORE Study - Study of Curette Use for Obtaining Restoration of Vertebral Body Anatomy in Balloon Kyphoplasty

NCT00810043
View directory record Official record
Conditions
Vertebral Body Compression Fractures (VCFs)
Interventions
Kyphon® Curette
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
50 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
3
States / cities
Temple Terrace, Florida • Middletown, Ohio • Burlington, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Phase 4 Interventional Results available

Unipedicular vs. Bipedicular Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures

NCT01383616
View directory record Official record
Conditions
Vertebral Compression Fracture
Interventions
Kyphon® Balloon Kyphoplasty (Kyphon Inc; Sunnydale, CA)
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years to 100 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 12:45 PM EDT
Terminated Phase 4 Interventional Results available

Anderson Circulating Tumor Cell Burden (CTCB) Study

NCT00819832
View directory record Official record
Conditions
Cancer, Spinal Disease, Vertebral Compression Fractures
Interventions
Kyphoplasty, Vertebroplasty, Cavity SpineWand
Procedure · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Jul 22, 2026, 12:45 PM EDT
Terminated Not applicable Interventional Results available

Vertebral Augmentation and Radiotherapy of Collapse Spinal Metastatic Cancer

NCT02376933
View directory record Official record
Conditions
Metastatic Cancers, Multiple Myeloma, Vertebral Fracture
Interventions
Vertebroplasty, Radiotherapy
Procedure · Radiation
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Jul 22, 2026, 12:45 PM EDT
Not listed Phase 1 Interventional

Combining Intraoperative Radiotherapy With Kyphoplasty for Treatment of Spinal Metastases

NCT02480036
View directory record Official record
Conditions
Spinal Metastasis
Interventions
IORT with Kyphoplasty, Intrabeam®
Radiation · Device
Lead sponsor
Loyola University
Other
Eligibility
50 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 6, 2020 · Synced Jul 22, 2026, 12:45 PM EDT
Recruiting No phase listed Observational

Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors

NCT07479199
View directory record Official record
Conditions
Thoracic Neoplasms, Lumbar Neoplasm
Interventions
kyphoplasty with Osteocool
Procedure
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs

NCT01871519
View directory record Official record
Conditions
Compression Fracture of Vertebral Body, Osteoporosis, Cancer
Interventions
Balloon kyphoplasty
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
65 Years and older
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
25
States / cities
Birmingham, Alabama • Fremont, California • Sacramento, California + 20 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Not applicable Interventional

To Evaluate Success of Cement Treatment of Spinal Compression Fractures

NCT00166374
View directory record Official record
Conditions
Back Pain
Interventions
balloon kyphoplasty
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2010 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Kypho-Intra Operative Radiation Therapy (IORT) for Localized Spine Metastasis, Phase I/II Study

NCT02987153
View directory record Official record
Conditions
Spinal Metastases
Interventions
Kypho-IORT
Radiation
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 22, 2026, 12:45 PM EDT
Recruiting Not applicable Interventional

Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure

NCT06471075
View directory record Official record
Conditions
Pain, Chronic Pain, Acute Pain
Interventions
Mindful Pain Management, Pain Psychoeducation
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Early Phase 1 Interventional

Basivertebral Nerve Block During Vertebral Augmentation: An Alternative Approach to Intraprocedural Pain Management

NCT04774029
View directory record Official record
Conditions
Vertebral Compression, Vertebra Compression Fracture, Vertebral Fracture
Interventions
Basivertebral nerve block, Lidocaine induced basivertebral nerve block
Procedure · Drug
Lead sponsor
Northwell Health
Other
Eligibility
50 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Port Jefferson, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2021 · Synced Jul 22, 2026, 12:45 PM EDT
Completed No phase listed Observational

Health-Related Quality of Life (QOL), Physical and Respiratory Function in Patients With Myeloma Affecting the Spine

NCT01006070
View directory record Official record
Conditions
Multiple Myeloma
Interventions
kyphoplasty
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2012 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Clinical Evaluation of the Crosstrees Pod™ in the Treatment of Pathologic Fracture of the Vertebral Body (Levels T4 - L5) in Adult Patients

NCT00933036
View directory record Official record
Conditions
Pathologic Fracture of the Vertebra Due to Osteoporosis
Interventions
Crosstrees Pod system for PVA
Device
Lead sponsor
Crosstrees Medical Inc.
Industry
Eligibility
50 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
9
States / cities
Long Beach, California • Washington D.C., District of Columbia • Clearwater, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2014 · Synced Jul 22, 2026, 12:45 PM EDT
Terminated Not applicable Interventional Results available

KAVIAR Study - Kyphoplasty And Vertebroplasty In the Augmentation and Restoration of Vertebral Body Compression Fractures

NCT00323609
View directory record Official record
Conditions
Vertebral Body Compression Fractures
Interventions
Vertebroplasty, Kyphoplasty
Procedure
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
25
States / cities
Scottsdale, Arizona • San Jose, California • Torrance, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 1, 2018 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Phase 3 Interventional Results available

The Kiva® System as a Vertebral Augmentation Treatment

NCT01123512
View directory record Official record
Conditions
Spinal Fractures, Fractures, Compression, Back Injuries
Interventions
Vertebral augmentation
Device
Lead sponsor
Benvenue Medical, Inc.
Industry
Eligibility
50 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
15
States / cities
Encinitas, California • Mountain View, California • Sacramento, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2014 · Synced Jul 22, 2026, 12:45 PM EDT
Completed Not applicable Interventional Results available

CAFE Study - Cancer Patient Fracture Evaluation

NCT00211237
View directory record Official record
Conditions
Cancer, Spinal Fractures
Interventions
Balloon Kyphoplasty, Non Surgical Management
Device · Other
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
9
States / cities
Escondido, California • Boulder, Colorado • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Jul 22, 2026, 12:45 PM EDT
Terminated Not applicable Interventional Results available

Evaluation of t-RFA and RF-TVA Prior to/Following Radiation Therapy to Treat Painful Metastatic Vertebral Body Tumor(s)

NCT02225223
View directory record Official record
Conditions
Metastatic Lesions in Vertebral Bodies
Interventions
STAR™ Tumor Ablation System, StabiliT® Vertebral Augmentation System
Device
Lead sponsor
Merit Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
14
States / cities
Los Angeles, California • Torrance, California • Tampa, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Jul 22, 2026, 12:45 PM EDT
Enrolling by invitation No phase listed Observational

A Prospective, Single-center, Observational Clinical Outcomes Study for Vertebral Compression Fractures Treated With the OsteoPearl Biological Allograft Implants

NCT07561489
View directory record Official record
Conditions
Kyphoplasty, Vertebroplasty, Vertebral Compression Fracture, Allograft, Back Pain
Interventions
Allograft
Biological
Lead sponsor
Lenoss Medical
Industry
Eligibility
50 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 22, 2026, 12:45 PM EDT