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Showing 1–24 of 137 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Labor Pain Clear all
Completed Not applicable Interventional Results available

Presence of a Companion During Performance of Neuraxial Labor Analgesia

NCT02982213
View directory record Official record
Conditions
Anxiety, Pain, Health Knowledge, Attitudes, Practice
Interventions
Companion Present
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery

NCT00380978
View directory record Official record
Conditions
Labor Pain, Pregnancy
Interventions
combined spinal epidural analgesia, late analgesia (systemic)
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,026 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stretching and Musculoskeletal Pain

NCT04617379
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Stretching
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
6
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Mankato, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Sep 5, 2026, 1:27 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor

NCT00871442
View directory record Official record
Conditions
Labor Pain
Interventions
No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
Other · Drug
Lead sponsor
Neil Roy Connelly, MD
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 17, 2015 · Synced Sep 5, 2026, 1:27 AM EDT
Completed No phase listed Observational

Comparison of Ultrasound Guided Low Epidural Catheter Placement With Standard Epidural Catheter Placement

NCT01182220
View directory record Official record
Conditions
Labor Pain
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo

NCT05485805
View directory record Official record
Conditions
Postoperative Dental Pain
Interventions
Naproxen sodium and caffeine (BAY2880376), Naproxen sodium (Aleve), Caffeine, Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
16 Years and older
Enrollment
541 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Sep 5, 2026, 1:27 AM EDT
Not listed Phase 4 Interventional

Intravenous Terbutaline to Facilitate Labor Epidural Catheter Placement

NCT01651962
View directory record Official record
Conditions
Labor Pain
Interventions
Terbutaline, Fentanyl, 0.9% NaCl
Drug
Lead sponsor
Kai Schoenhage
Other
Eligibility
18 Years to 53 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lower Limb Compression Prevents Hypotension After Epidural in Labor

NCT04750486
View directory record Official record
Conditions
Labor Pain, Maternal Hypotension
Interventions
Sequential compression devices
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Ear Acupuncture for Pain and Anxiety Management in Early Labor

NCT06678893
View directory record Official record
Conditions
Pain, Anxiety, Labor
Interventions
Acupuncture Needle on an adhesive, Adhesives
Device
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Sep 5, 2026, 1:27 AM EDT
Enrolling by invitation Not applicable Interventional

Evaluation and Modification of Surgeon Ergonomics in the Operation Room Using Artificial Intelligence Analytics

NCT06576570
View directory record Official record
Conditions
Work Related Upper Limb Disorder, Musculoskeletal Pain
Interventions
Education presentation of surgical ergonomics, Summary of Ergonomic Measurement System
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 5, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Standardizing Emergency Work-ups Around Risk Data

NCT03286179
View directory record Official record
Conditions
Acute Coronary Syndrome, Chest Pain, Risk Reduction
Interventions
modified HEART score and/or Emergency Department Assessment of Chest pain Risk Score (EDACS)
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
13,419 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
12
States / cities
Antioch, California • Fremont, California • Oakland, California + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Sep 5, 2026, 1:27 AM EDT
Not yet recruiting Not applicable Interventional

The Use of Electrical Stimulation for Determination of Epidural Catheter Placement

NCT06055686
View directory record Official record
Conditions
Obstetric Pain, Anesthesia, Local
Interventions
Electrical Epidural Stimulation Test
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Not applicable Interventional

The Effect of a Culturally Sensitive Educational Intervention on Acceptance of Neuraxial Anesthesia

NCT02672397
View directory record Official record
Conditions
Labor Pain
Interventions
Additional Epidural Education
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 5, 2026, 1:27 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

ED90 of Bupivacaine After Lidocaine Test Dose With DPE and EPL

NCT06146842
View directory record Official record
Conditions
Labor Pain
Interventions
Bupivacaine Hydrochloride
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Modifiable Work and Movement Solutions Low Back Pain in Seafood Workers

NCT03524378
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Ergonomic and movement modifications
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Cedar Key, Florida • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery

NCT05498025
View directory record Official record
Conditions
Pain, Acute, Opioid Misuse, Obstetric Pain, Cesarean Section Complications
Interventions
Deterra activated charcoal pouch
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Sep 5, 2026, 1:27 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

LOTUS Trial: Lumbar Ultrasound in Obstetric Patients With BMI > 40

NCT06305260
View directory record Official record
Conditions
Obesity, Morbid, Labor Pain
Interventions
Lumbar Ultrasound
Diagnostic Test
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Sep 5, 2026, 1:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation

NCT03103100
View directory record Official record
Conditions
Labor Pain
Interventions
1% Lidocaine, 0.25% Bupivacaine, Bupivacaine plus Lidocaine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 60 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 30, 2020 · Synced Sep 5, 2026, 1:27 AM EDT
Terminated Phase 4 Interventional

Epidural Fentanyl for 2nd Stage Labor Analgesia

NCT03120780
View directory record Official record
Conditions
Labor Pain
Interventions
Fentanyl 20 mcg, Fentanyl 100 mcg
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 5, 2026, 1:27 AM EDT
Terminated Phase 2 Interventional Results available

Study to Gather Information How Well Three Different Doses of BAY1817080 Given Twice Daily Over 12 Weeks Work in Comparison to an Inactive Pill (Placebo) and Elagolix in Women Suffering From Pain Related to a Condition Where the Tissue That Usually Grows Inside the Womb Grows Outside of the Womb

NCT04614246
View directory record Official record
Conditions
Endometriosis
Interventions
BAY1817080, Elagolix, Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older · Female only
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
47
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 5, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Therapeutic Rest to Delay Admission in Early Labor: A Prospective Study on Morphine Sleep

NCT03539562
View directory record Official record
Conditions
Labor Pain, Early Labor
Interventions
Morphine Sulfate and Promethazine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 5, 2026, 1:27 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Intracervical Balloon Placement With Nitrous Oxide Administration

NCT06498908
View directory record Official record
Conditions
Labor Pain, Induced; Birth
Interventions
Nitrous oxide, Oxygen
Drug
Lead sponsor
Olivia Sher
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 5, 2026, 1:27 AM EDT
Terminated No phase listed Observational

Anticipated Versus Actual Patient and Caregiver Burden Following Ambulatory Orthopedic Surgery

NCT02550886
View directory record Official record
Conditions
Stress, Psychological, Pain
Interventions
Survey
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Sep 5, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Physical Effects of Pain Catastrophizing in Labor

NCT01012466
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 28, 2019 · Synced Sep 5, 2026, 1:27 AM EDT