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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Language Impairment Clear all
Completed Phase 3 Interventional

Precision Medicine Approach for Early Dementia & Mild Cognitive Impairment

NCT05894954
View directory record Official record
Conditions
Mild Cognitive Impairment, Dementia, Mild
Interventions
Precision Medicine Approach, Hormones and Medications tailored to lab tests, combined with devices that support stress management and brain exercises, Standard-of-Care, Lifestyle including diet, exercise, stress management
Dietary Supplement · Combination Product · Behavioral
Lead sponsor
Alzheimer's Prevention and Reversal Project, Inc.
Other
Eligibility
45 Years to 76 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Folsom, California • San Rafael, California • Walnut Creek, California + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Assessing an Animal-Assisted Treatment Program for Adults With Aphasia: The Persons With Aphasia Training Dogs Program

NCT04610346
View directory record Official record
Conditions
Aphasia
Interventions
Persons with Aphasia Training Dogs Program
Behavioral
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
21 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment

NCT02809118
View directory record Official record
Conditions
Hearing Loss, Idiopathic Sudden Sensorineural
Interventions
AM-111 0.4 mg/ml, AM-111 0.8 mg/ml, Placebo
Drug · Other
Lead sponsor
Auris Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
38
States / cities
Birmingham, Alabama • Escondido, California • Fresno, California + 34 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional

Voiceitt for People With Impairments in Speech

NCT06874322
View directory record Official record
Conditions
Speech Impairment, Speech Disorder
Interventions
Voiceitt
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Semantic Learning Deficits in School Age Children With Developmental Language Disorder

NCT04508699
View directory record Official record
Conditions
Developmental Language Disorder
Interventions
semantic learning
Other
Lead sponsor
San Diego State University
Other
Eligibility
10 Years to 12 Years
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurofeedback Intervention for Reading Deficits in Subacute Stroke

NCT04875936
View directory record Official record
Conditions
Stroke, Dyslexia, Acquired
Interventions
Motor Imagery and Real-Time fMRI Neurofeedback, Motor Imagery and Sham fMRI Neurofeedback
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Phase 2 Interventional Results available

Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia

NCT03651700
View directory record Official record
Conditions
Aphasia
Interventions
Active TMS, Sham TMS, CILT
Device · Behavioral
Lead sponsor
H. Branch Coslett
Other
Eligibility
18 Years to 80 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Aphasia Rehabilitation: Modulating Cues, Feedback & Practice

NCT01597037
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Script training
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional

Stimulating the Aging Brain Using Brain and Sensory Stimulation

NCT07650188
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
tACS or multisensory stimulation
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
45 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2035
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Determining Optimal Treatment Intensity for Children With Language Impairment

NCT04501536
View directory record Official record
Conditions
Language Impairment
Interventions
Word Learning Intervention
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
5 Years to 8 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Columbus, Ohio • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech

NCT05437159
View directory record Official record
Conditions
Stuttering, Developmental, Aphasia, Primary Progressive
Interventions
Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords, Anodal tDCS, Sham tDCS, Learning of non-native phoneme combinations: 8 training sessions
Behavioral · Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
6 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional

Neuroplasticity Biomarkers in Aphasia

NCT06471127
View directory record Official record
Conditions
Aphasia, Language, Stroke
Interventions
Pseudoword learning paradigm task
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
40 Years to 90 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Phase 4 Interventional

Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

NCT01818661
View directory record Official record
Conditions
PPA, Non-fluent Aphasia, Apraxia of Speech, Primary Progressive Non-fluent Aphasia, Primary Progressive Aphasia
Interventions
AV-1451
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Active, not recruiting Phase 2 Interventional

Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium

NCT04060017
View directory record Official record
Conditions
Autism Spectrum Disorder, Language Disorders
Interventions
Levoleucovorin Calcium, Placebo
Drug · Other
Lead sponsor
Southwest Autism Research & Resource Center
Other
Eligibility
30 Months to 60 Months
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Phoenix, Arizona • Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Cognitive Therapy to Improve Word Finding

NCT00494520
View directory record Official record
Conditions
Anomia, Aphasia, Traumatic Brain Injury, Cerebrovascular Accident
Interventions
Errorful training condition, Errorless training condition
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Jul 21, 2026, 2:19 PM EDT
Completed No phase listed Observational

Treatment for Reading and Writing Deficits Following Acquired Brain Injury

NCT03662243
View directory record Official record
Conditions
Acquired Brain Injury, Alexia, Agraphia
Interventions
Multicomponent reading and writing treatment
Behavioral
Lead sponsor
Quality Living, Inc.
Other
Eligibility
14 Years to 70 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Executive Function in Early Childhood

NCT03713125
View directory record Official record
Conditions
Reading Disability
Interventions
Reading Tutoring
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
4 Years to 9 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Theory-Driven Treatment of Language and Cognitive Processes in Aphasia

NCT02664506
View directory record Official record
Conditions
Aphasia
Interventions
Word repetition after a time delay.
Behavioral
Lead sponsor
Temple University
Other
Eligibility
21 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Jul 21, 2026, 2:19 PM EDT
Not listed Not applicable Interventional

Reading Remediation and Outcomes in Detention

NCT03261076
View directory record Official record
Conditions
Specific Learning Disorder (MeSH Unique ID: D000067559), Dyslexia (MeSH Unique ID: D004410), Conduct Disorder (MeSH Unique ID: D019955)
Interventions
Strategies Enhancing Reading in Older Underperf. Students
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
14 Years to 16 Years · Male only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Jul 21, 2026, 2:19 PM EDT
Not listed Not applicable Interventional

Timing of Transcranial Direct Current Stimulation (tDCS) Combined With Speech and Language Therapy (SLT)

NCT03773406
View directory record Official record
Conditions
Aphasia
Interventions
Offline tDCS-before therapy, Sham tDCS, Offline tDCS-after therapy, Online tDCS
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners

NCT06613204
View directory record Official record
Conditions
Frontotemporal Dementia, Caregiver Burden, Primary Progressive Aphasia (PPA), Corticobasal Syndrome
Interventions
STELLA-FTD Control, STELLA-FTD Test
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
640 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Phase 2 Interventional Results available

Effect of Repetitive Transcranial Magnetic Stimulation on Language in Alzheimer's Disease

NCT00814697
View directory record Official record
Conditions
Alzheimer's Disease, Aphasia, Dementia
Interventions
Repetitive Transcranial Magnetic Coil Stimulation (rTMS)
Device
Lead sponsor
The New York Memory Services
Other
Eligibility
50 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2014 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional

Treatment for /s/ Production Errors in Children With Speech Sound Errors

NCT07214480
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Motor-based speech treatment
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
7 Years to 11 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)

NCT02554513
View directory record Official record
Conditions
Apraxia of Speech, Aphasia, Acquired, Speech Disorders
Interventions
EPG Tx, SPT
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Jul 21, 2026, 2:19 PM EDT