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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:30 PM EST

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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Laryngopharyngeal Reflux Clear all

Conditions: Laryngopharyngeal Reflux, Hypertrophy of Lingual Tonsil
Interventions: dexlansoprazole; Drug
Lead sponsor: Advanced Center for Specialty Care; Other
Eligibility: 18 Years to 59 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Laryngopharyngeal Reflux
Interventions: Prevacid; Drug
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Gastroesophageal Reflux
Interventions: Dexlansoprazole MR QD; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 52
States / cities: Hueytown, Alabama • Chandler, Arizona • Sierra Vista, Arizona + 49 more

Conditions: Extraesophageal Symptoms, Cough, Throat Clearing, Hoarseness, Difficulty Swallowing
Interventions: Screening for Barrett's Esophagus; Diagnostic Test
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years to 90 Years
Enrollment: 295 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2011
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Laryngopharyngeal Reflux, Throat Pain
Interventions: Omeprazole; Drug
Lead sponsor: Ascension Health; Industry
Eligibility: 7 Years to 17 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Grand Blanc, Michigan

Conditions: Larynx Disease, Gastroesophageal Reflux
Interventions: Esophageal and Laryngeal biopsies, egd with biopsy; Procedure
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Gastroesophageal Reflux, Laryngopharyngeal Reflux
Interventions: Reflux Band® Upper Esophageal Sphincter (UES) Assist Device; Diagnostic Test
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 89 Years
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Postoperative Ileus, Postoperative Nausea, Postoperative Complications, Postoperative Nausea and Vomiting, Postoperative Vomiting, Aspiration Vomitus
Interventions: Bedside gastric ultrasound; Diagnostic Test
Lead sponsor: Eric Schwenk; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Larynx Disease, Gastroesophageal Reflux
Interventions: Prevacid, Esophageal and Laryngeal Biopsies; Drug · Procedure
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Laryngopharyngeal Reflux
Interventions: Dx-pH probe; Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 1 Month to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Laryngopharyngeal Reflux
Interventions: dexlansoprazole, Placebo; Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Laryngopharyngeal Reflux
Interventions: Fosamprenavir Calcium, Placebo; Drug · Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years to 64 Years
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Gastroesophageal Reflux
Interventions: Dexlansoprazole MR; Drug
Lead sponsor: Takeda; Industry
Eligibility: 12 Years to 17 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 3
States / cities: Anaheim, California • Cypress, California • Overland Park, Kansas

Conditions: Laryngopharyngeal Reflux
Interventions: Prevacid 30mg BID, Lifestyle changes of exercise and diet changes for weight loss and avoidance of reflux inducing foods.; Drug · Behavioral
Lead sponsor: Hodge, Kenneth M., M.D.; Individual
Eligibility: 18 Years and older
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: IPF, Reflux
Interventions: Not listed
Lead sponsor: National Jewish Health; Other
Eligibility: 40 Years to 95 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Vasomotor Rhinitis
Interventions: esomeprazole, placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Gastric Content Aspiration
Interventions: Esophagogastroduodenoscopy; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Gastroesophageal Reflux Disease (GERD), Laryngopharyngeal Reflux (LPR), Reflux Disease, Gastro-Esophageal, Motility Disorder
Interventions: Transoral Incisionless Fundoplication; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Laryngopharyngeal Reflux, Cough, Throat Clearing, Dysphonia, Reflux
Interventions: Omeprazole 40 MG, Laryngeal Recalibration Therapy, GERD Lifestyle Recommendations; Drug · Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 89 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Deigo, California

Conditions: Respiratory Aspiration of Gastric Contents
Interventions: Interview questionnaire, Gastric ultrasound exam; Behavioral · Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 99 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Laryngopharyngeal Reflux, Zenker's Diverticulum
Interventions: Cricopharyngeal myotomy, PH probe Testing; Procedure · Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Gastroesophageal Reflux Disease, Barrett Esophagus, Laryngopharyngeal Reflux, Esophagitis
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 9
States / cities: Orange, California • Baltimore, Maryland • Rochester, Minnesota + 6 more

Conditions: Gastroesophageal Reflux
Interventions: Nexium, Sugar Pill; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Laryngopharyngeal Reflux
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Atlanta, Georgia

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Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy

Twice Daily Prevacid for the Treatment of Laryngopharyngeal Reflux

Efficacy of Dexlansoprazole MR on Heartburn Control in Participants Previously Receiving Twice Daily Proton Pump Inhibitor Therapy

Screening for Barrett's Esophagus in Otolaryngology Patients

Anti-reflux Control to Decrease Post Tonsillectomy Pain

Esophageal and Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux

Precision Approach to PPI Therapy in Gastroesophageal Reflux Disease

Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function

Do Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux Predict Response to Treatment?

A New Nasopharyngeal pH Probe for Diagnosis of Laryngopharyngeal Reflux

The Effects of Dexlansoprazole for the Treatment of Throat-Related Reflux

Fosamprenavir for Laryngopharyngeal Upper Airway Tissue Treatment and Enzyme Reduction

Pharmacokinetic and Safety of Dexlansoprazole in Adolescents With Gastroesophageal Reflux Disease

Prevacid vs Lifestyle Modifications for the Treatment of LPR

The Role of Laryngopharyngeal Reflux in IPF

Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial

GLP-1 Receptor Agonist Use and Incidence of Retained Gastric Food on Endoscopy

Transoral Incisionless Fundoplication (TIF) for Laryngopharyngeal Reflux (LPR) Patients

The Mechanism Versus PPI Trial

Gastric Ultrasound for Estimation of the Aspiration Risk Study

Laryngopharyngeal Reflux Before and After Cricopharyngeal Myotomy

The Johns Hopkins Heartburn Center Registry

Which Supraesophageal Reflux Symptoms Reliably Respond to Proton-Pump-Inhibitor (PPI) Therapy

Study of an Oropharyngeal Aerosolized pH Probe for Diagnosing Laryngopharyngeal Reflux (LPR)