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ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:41 PM EDT

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Showing 1–24 of 91 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Longevity Clear all
Completed Phase 2 Interventional Results available

Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study

NCT04080544
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Decline
Interventions
[18F]AV-1451, Positron Emission Tomography
Drug · Procedure
Lead sponsor
Neil M Rofsky, MD, MHA
Other
Eligibility
38 Years to 96 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music Therapy at TMH Infusion Center

NCT06450626
View directory record Official record
Conditions
Music Therapy
Interventions
Listening Music Intervention
Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 2, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Not listed Not applicable Interventional

Effect of a Community-based Nursing Intervention on Mortality in Chronically Ill Older Adults

NCT01071967
View directory record Official record
Conditions
Heart Failure, Coronary Disease, Diabetes Mellitus, Asthma, Hypertension, Hypercholesterolemia
Interventions
Community-based nurse care management
Other
Lead sponsor
Health Quality Partners
Other
Eligibility
65 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Doylestown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2013 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Oxytocin and Social Behavior Over the Lifespan

NCT00914953
View directory record Official record
Conditions
Social Activity
Interventions
oxytocin (Pitocin)
Drug
Lead sponsor
Claremont Graduate University
Other
Eligibility
50 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2012 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Healthy Elderly Longevity Cohort

NCT01004133
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
80 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2030
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Impact of a Novel Brain Longevity Supplement Containing the Postbiotic Urolithin A (Mitopure) on Cognitive Function and Related Health Outcomes

NCT07060898
View directory record Official record
Conditions
Aging, Cognitive Decline, Brain Fog, Cognitive Function
Interventions
Active Product, Placebo Product
Dietary Supplement
Lead sponsor
Amazentis SA
Industry
Eligibility
40 Years and older
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Encinitas, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Study of Acarbose in Longevity

NCT02953093
View directory record Official record
Conditions
Aging
Interventions
Acarbose, Placebo
Drug · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
60 Years to 100 Years · Male only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Active, not recruiting No phase listed Observational

A Clinical Observational Study of SARS-CoV-2 Specific CD8 T-Cell Responses to COVID-19 Vaccines in Humans

NCT04852289
View directory record Official record
Conditions
COVID-19
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years to 99 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cadence and Intensity Across the Adult Lifespan

NCT02650258
View directory record Official record
Conditions
Aging, Walking, Motor Activity, Activities of Daily Living
Interventions
treadmill walking
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
21 Years to 85 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Jul 21, 2026, 4:41 PM EDT
Not listed No phase listed Observational

Improving Cancer Screening and Prevention During the COVID-19 Pandemic in Underserved Populations of Rhode Island

NCT04587258
View directory record Official record
Conditions
Breast Cancer, Colorectal Cancer, Covid19
Interventions
Informational videos and social media campaigns encouraging cancer screening.
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting Phase 2Phase 3 Interventional

Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation

NCT07092618
View directory record Official record
Conditions
Longevity, GLP-1, Geroscience, Aging
Interventions
Metformin, Rapamycin, Naltrexone, Vitamin C
Drug · Dietary Supplement
Lead sponsor
AgelessRx
Industry
Eligibility
40 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Expression of Longevity Genes in Response to Extended Fasting

NCT01059760
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Fasting First, Fed First
Behavioral
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jul 16, 2017 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting Phase 4 Interventional

Allograft Dysfunction in Heart Transplant

NCT03102125
View directory record Official record
Conditions
Heart Transplant Failure and Rejection
Interventions
Regadenoson
Drug
Lead sponsor
Paul Kim
Other
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Kaempferol Absorption and Pharmacokinetics Evaluation

NCT07322406
View directory record Official record
Conditions
No Disease, Mitochondria Health, Longevity, Pharmacokinetics and Biological Absorption of Kaempferol in Healthy Adult, Healthy Volunteers
Interventions
Kaempferol
Dietary Supplement
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
New York, New York • Chapel Hill, North Carolina • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Enrolling by invitation Not applicable Interventional

G7 Dual Mobility With Vivacit-E or Longevity PMCF

NCT05548972
View directory record Official record
Conditions
Hip Osteoarthritis, Rheumatoid Arthritis, Joint Diseases, Avascular Necrosis, Dislocation, Hip, Femoral Neck Fractures, Trochanteric Fractures, Revision Surgeries
Interventions
G7 Dual Mobility with Vivacit-E bearing, G7 Dual Mobility Longevity bearing
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 80 Years
Enrollment
358 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2037
U.S. locations
6
States / cities
Little Rock, Arkansas • Denver, Colorado • Jersey City, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Recovery and Lifespan of Red Blood Cells From Pathogen-reduced, Stored Blood Units

NCT03384407
View directory record Official record
Conditions
Red Cell Survival in Healthy Volunteers
Interventions
Red cell survival in INTERCEPT treated red cells
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Jul 21, 2026, 4:41 PM EDT
Terminated No phase listed Observational

MDR - Longevity IT Oblique and Offset Liners

NCT05980234
View directory record Official record
Conditions
Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis, Protrusio Acetabuli, Traumatic Arthritis, Slipped Capital Femoral Epiphyses, Fracture of the Pelvis, Diastrophic Variant, Osteoarthritis, Fused Hip
Interventions
Total Hip Arthroplasty with Longevity IT Oblique Liners, Total Hip Arthroplasty with Longevity IT Offset Liners
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

The Effect of Prophylactic FFP Administration on ECMO Circuit Longevity

NCT01903863
View directory record Official record
Conditions
Extracorporeal Membrane Oxygenation
Interventions
Fresh frozen plasma
Biological
Lead sponsor
Duke University
Other
Eligibility
1 Day to 18 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Jul 21, 2026, 4:41 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Iterative Design Trial to Assess Dietary Supplements and Other Aging-targeted Therapies

NCT07202403
View directory record Official record
Conditions
Aging, Longevity
Interventions
Spermidine
Dietary Supplement
Lead sponsor
Atria Research and Global Health Institute (ARGHI)
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Completed No phase listed Observational

Comparative Renal Function of Young (18-45 Years) and Ageing (55 Years and Above) Kidney Donors

NCT00846729
View directory record Official record
Conditions
Kidney Diseases
Interventions
CT angiogram of the remaining kidney., Kidney Function study using Iothalamate & PAH as clearance markers
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2018 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

A Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1

NCT07015437
View directory record Official record
Conditions
Healthy Subjects
Interventions
INTERCEPT Blood System for RBCs, Infusion of autologous radiolabeled RBCs
Device · Other
Lead sponsor
Cerus Corporation
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Cincinnati, Ohio • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

100-Year Human Aging Study

NCT07563777
View directory record Official record
Conditions
Aging, Aging Well, All-Cause Mortality, Mortality, Metabolic Syndrome, Cardiovascular Diseases, Cognitive Dysfunction, Musculoskeletal Diseases, Neoplasms, Frailty, Activities of Daily Living, Health-Related Quality of Life, Disability Physical, Neuro-Degenerative Disease, Dementia
Interventions
Comprehensive Multi-System Clinical Screening
Diagnostic Test
Lead sponsor
Longevity Metrics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2099
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

iVS-1 Probiotic Intervention Targeting Biological Aging in Midlife Adults

NCT07407894
View directory record Official record
Conditions
Healthy Aging, Anti Aging
Interventions
Bifidobacterium adolescentis iVS-1, Placebo
Dietary Supplement
Lead sponsor
Synbiotic Health
Industry
Eligibility
40 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Port Richey, Florida
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jul 21, 2026, 4:41 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Participatory Evaluation (of) Aging (With) Rapamycin (for) Longevity Study

NCT04488601
View directory record Official record
Conditions
Aging
Interventions
Rapamycin, Placebo
Drug
Lead sponsor
AgelessRx
Industry
Eligibility
50 Years to 85 Years
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Jul 21, 2026, 4:41 PM EDT