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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mastectomy Clear all
Completed Phase 1 Interventional

Pre-Operative, Single-Dose Ipilimumab and/or Cryoablation in Early Stage/Resectable Breast Cancer

NCT01502592
View directory record Official record
Conditions
Breast Cancer, Invasive Adenocarcinoma of the Breast
Interventions
Cryoablation, Ipilimumab
Procedure · Biological
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2016 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Phase 2 Interventional Results available

Transdermal or Oral Telapristone Acetate in Treating Patients Undergoing Mastectomy

NCT02314156
View directory record Official record
Conditions
BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Ductal Breast Carcinoma In Situ, Lobular Breast Carcinoma In Situ, Stage 0 Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer
Interventions
Telapristone Acetate, Placebo, Laboratory Biomarker Analysis, Questionnaire Administration
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
3
States / cities
West Hollywood, California • Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Jul 22, 2026, 8:28 AM EDT
Withdrawn Not applicable Interventional

Treatment of Benign Breast Deformities and Post-Segmental Mastectomy Breast Deformities With Autologous Fat Grafting (AFT)

NCT01756092
View directory record Official record
Conditions
Breast Cancer, Lumpectomy, Mastectomy, Segmental
Interventions
Autologous Fat Graft
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2016 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy

NCT04019834
View directory record Official record
Conditions
Breast Cancer, Mastectomy, Anesthesia, Local, Narcotic Use
Interventions
regional nerve block with local anesthesia of bupivacaine with steroid, Placebo regional nerveblock with normal saline
Drug · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Not applicable Interventional Results available

Bioprosthetic Mesh to Expand the Lower Pole in Tissue Expander Reconstruction

NCT01310075
View directory record Official record
Conditions
Breast Cancer
Interventions
Alloderm, Surgimend
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Not applicable Interventional

The Effect of Mirror Education for Women Undergoing Mastectomy

NCT01642628
View directory record Official record
Conditions
Emotional Distress, Anxiety, Depression
Interventions
Mirror Education
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Jul 22, 2026, 8:28 AM EDT
Recruiting Not applicable Interventional

Self-Determination Theory-informed Occupational Therapy Program to Increase Physical Activity Among Survivors of Breast Cancer

NCT06671730
View directory record Official record
Conditions
Breast Cancer Survivor
Interventions
8-Week Telehealth-based Occupational Therapy Program
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Not applicable Interventional

Selective Image Guided Resection of Axillary Lymph Nodes

NCT01880645
View directory record Official record
Conditions
Breast Cancer
Interventions
Fine Needle Aspiration (FNA), Ultrasound, Breast Surgery + Lymph Node Removal
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2015 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Early Phase 1 Interventional

64 Cu-DOTA-alendronate PET Imaging in Localizing and Characterizing Breast Calcifications in Participants Before Undergoing Mastectomy

NCT03542695
View directory record Official record
Conditions
Breast Carcinoma, Calcification
Interventions
Computed Tomography, Copper Cu-64-DOTA-alendronate, Pharmacokinetic Study, Positron Emission Tomography
Procedure · Drug · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2024 · Synced Jul 22, 2026, 8:28 AM EDT
Active, not recruiting No phase listed Observational

Open Nipple Sparing Mastectomy (NSM)

NCT04447339
View directory record Official record
Conditions
Nipple Sparing Mastectomy
Interventions
Nipple Sparing Mastectomy
Procedure
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
5
States / cities
Evanston, Illinois • Rochester, Minnesota • Queens, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jul 22, 2026, 8:28 AM EDT
Completed No phase listed Observational

The Effects of Radiation in Reconstructed Breasts

NCT01292772
View directory record Official record
Conditions
Breast Cancer
Interventions
contract-enhanced MRI, Unilateral Adjuvant Radiation Therapy
Procedure · Radiation
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Phase 4 Interventional Results available

Acellular Dermal Matrix in Tissue Expander Breast Reconstruction: A Prospective, Randomized, Clinical Trial Comparing SurgiMend PRS and AlloDerm RTU

NCT01781299
View directory record Official record
Conditions
Breast Cancer, Mastectomy
Interventions
AlloDerm RTU, SurgiMend PRS
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Jul 22, 2026, 8:28 AM EDT
Completed No phase listed Observational

Evaluation of SOMAVAC 100 Sustained Vacuum System

NCT04845256
View directory record Official record
Conditions
Breast Cancer
Interventions
SOMAVAC 100 Sustained Vacuum System
Device
Lead sponsor
University of Tennessee
Other
Eligibility
21 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Jul 22, 2026, 8:28 AM EDT
Not listed Not applicable Interventional

The Use of Laser-Assisted Indocyanine Green Dye Angiography to Predict Mastectomy Skin Flap Viability

NCT01554267
View directory record Official record
Conditions
Breast Cancer, Breast Reconstruction, Mastectomy
Interventions
Laser-Assisted ICG Dye Angiography (SPY System)
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2014 · Synced Jul 22, 2026, 8:28 AM EDT
Recruiting Not applicable Interventional

Silk Bioprotein as a Wound Dressing for Double-Incision Mastectomy

NCT06921148
View directory record Official record
Conditions
Wound Healing
Interventions
Sylk Wound Dressing, Dermabond/Prineo Dressing
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 22, 2026, 8:28 AM EDT
Withdrawn No phase listed Observational

Markers for Predicting Risk of Breast Cancer in Women of Different Races

NCT02574546
View directory record Official record
Conditions
Breast Cancer
Interventions
Mastectomy
Procedure
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Jul 22, 2026, 8:28 AM EDT
Not listed Phase 3 Interventional

Application Of Autologous Blood Products During Modified Radical Mastectomy

NCT00802477
View directory record Official record
Conditions
Mastectomy
Interventions
Application of autologous blood products., Standard Modified Radical Mastectomy
Procedure
Lead sponsor
Marshall University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2011 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Botulinum Toxin A (Botox) in Tissue Expander Breast Reconstruction

NCT01591746
View directory record Official record
Conditions
Breast Cancer, Pain, Postoperative, BRCA1 Mutation, BRCA2 Mutation, Breast Diseases, Neoplasms
Interventions
Botulinum Toxin Type A, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Jul 22, 2026, 8:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

BC Risk Assessment Before Top Surgery

NCT06239766
View directory record Official record
Conditions
Breast Cancer, Risk Reduction
Interventions
Breast Cancer Risk Assessment
Diagnostic Test
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Jul 22, 2026, 8:28 AM EDT
Completed Phase 4 Interventional Results available

Use of Pulsed Electromagnetic Fields (PEMF) After Breast Reconstruction Surgery

NCT01262599
View directory record Official record
Conditions
Other Reconstructive Surgery
Interventions
Sham PEMF Device, Ivivi Torino II PEMF Device
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Jul 22, 2026, 8:28 AM EDT
Completed No phase listed Observational

Evaluating Mepitel in Post-mastectomy Patients and the Role of the Skin Microbiome in Radiation Dermatitis

NCT03519438
View directory record Official record
Conditions
Breast Cancer
Interventions
Mepitel
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Jul 22, 2026, 8:28 AM EDT
Terminated Not applicable Interventional

Progressive Tension Sutures in Gender Affirming Mastectomy

NCT04818580
View directory record Official record
Conditions
Hematoma, Seroma
Interventions
Progressive Tension Sutures
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2023 · Synced Jul 22, 2026, 8:28 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine for Breast Surgery

NCT03383198
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Liposomal bupivacaine right injection, Liposomal bupivacaine left injection
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Jul 22, 2026, 8:28 AM EDT
Completed No phase listed Observational

A Pilot Study to Evaluate Nipple-Areolar Complex (NAC) Sparing Mastectomy

NCT00539227
View directory record Official record
Conditions
Breast Cancer
Interventions
NAC Sparing Mastectomy, Questionnaire
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2013 · Synced Jul 22, 2026, 8:28 AM EDT