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Showing 1–24 of 294 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Maternal Complications Clear all
Enrolling by invitation No phase listed Observational

EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 3)

NCT06160349
View directory record Official record
Conditions
Maternal Sepsis, Infections
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Exposure to Stress, Postpartum Mood, Adverse Life Events, and Hormonal Function Among Latinas (SEPAH Latina)

NCT01912833
View directory record Official record
Conditions
Postpartum Depression
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 7, 2014 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)

NCT07214597
View directory record Official record
Conditions
Postpartum Depression (PPD), Self-Efficacy, Parental Anxiety, Engagement, Patient, Usability, Length of Stay
Interventions
VoiceLove mobile phone application
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Early Initiation of Milk Expression in Mothers of Very Low Birth Weight Infants

NCT01892085
View directory record Official record
Conditions
Breast Milk Expression
Interventions
Early initiation, Intermediate expression, Late initiation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Phase 1 Interventional

The Use of Eculizumab in HELLP Syndrome

NCT04103489
View directory record Official record
Conditions
HELLP Syndrome (HELLP), Third Trimester, Complement Abnormality, Morbidity;Newborn, Maternal Injury, Preeclampsia Severe
Interventions
Eculizumab
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

DHA Supplementation for Lactating Mothers

NCT01732874
View directory record Official record
Conditions
Docosohexaenoic Acid Supplementation of Mothers to
Interventions
Expecta 200 mg, Expecta 1 gram
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 45 Years · Female only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional

Healing, Equity, Advocacy and Respect for Mamas

NCT06273436
View directory record Official record
Conditions
Postpartum Complication
Interventions
H.E.A.R. for Mamas
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years to 49 Years · Female only
Enrollment
2,894 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Phase 2 Interventional Results available

Recombinant Human Prolactin for Lactation Induction

NCT00181610
View directory record Official record
Conditions
Lactation
Interventions
Recombinant Human Prolactin, Recombinant human prolactin, Normal Saline
Drug · Biological
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional

Providing an Optimized and Empowered Pregnancy for You (POPPY) Aim 3: Randomized Controlled Trial

NCT06510075
View directory record Official record
Conditions
Pregnancy Complications, Maternal Distress, Adverse Birth Outcomes, Infant Conditions
Interventions
Digital Health intervention, Community Health Worker, Digital Health Intervention plus Community Health Worker
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years to 49 Years · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Oral Intake During Labor

NCT03276741
View directory record Official record
Conditions
Labor Complication, Food Aspiration, Complication of Anesthesia, Satisfaction
Interventions
gastric soft/bland diet
Dietary Supplement
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study

NCT04154423
View directory record Official record
Conditions
Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety, Depression, Postpartum, Satisfaction, Patient, Health Problems in Pregnancy
Interventions
Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Female only
Enrollment
678 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Fresno, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms: Impact on Child Development

NCT05400161
View directory record Official record
Conditions
Postpartum Depression, Parenting, Parent-Child Relations, Child Development
Interventions
MoodGym, Social Media-Based Parenting Program
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Lactation Success in Black Mothers of Critically Ill Infants

NCT05147987
View directory record Official record
Conditions
Insufficient Lactation
Interventions
Hands free wearable breast pump
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks

NCT05674799
View directory record Official record
Conditions
Overweight or Obesity
Interventions
NDPP-NextGen
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting No phase listed Observational

Bempedoic Acid Pregnancy Surveillance Program

NCT05103254
View directory record Official record
Conditions
Pregnancy, Hyperlipidemias
Interventions
Bempedoic Acid, Bempedoic Acid / Ezetimibe
Drug
Lead sponsor
Esperion Therapeutics, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Timeline
2021 – 2032
U.S. locations
1
States / cities
Morrisville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Encourage Healthy Families

NCT01823367
View directory record Official record
Conditions
Gestational Diabetes Mellitus, Pre-diabetes
Interventions
Diabetes Prevention Program (DPP)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Phase 1 Interventional

A Phase I Study of Safety and Pharmacokinetics of Nevirapine in HIV-1 Infected Pregnant Women and Neonates Born to HIV-1 Infected Mothers

NCT00000808
View directory record Official record
Conditions
HIV Infections, Pregnancy
Interventions
Nevirapine
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years to 60 Years · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1998
U.S. locations
15
States / cities
La Jolla, California • Los Angeles, California • San Francisco, California + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Proyecto BEBE: The Effect of Babywearing Education on Breastfeeding Exclusivity

NCT04376021
View directory record Official record
Conditions
Breastfeeding, Exclusive, Mother-Infant Interaction, Postpartum Depression
Interventions
Babywearing
Behavioral
Lead sponsor
Nurturely
Other
Eligibility
18 Years and older · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 5, 2026, 4:28 PM EDT
Active, not recruiting Not applicable Interventional

Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial

NCT05655936
View directory record Official record
Conditions
Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Hypertension, Obesity, Overweight, Nutrition Disorders, Vascular Diseases, Cardiovascular Diseases, Pre-Eclampsia, Eclampsia, Gestational Hypertension
Interventions
Heart Health Doula Intervention Program, Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional

The Mom and Infant Outcomes (MOMI) Study

NCT06277661
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Cardiometabolic Syndrome
Interventions
MOMI PODS, Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
Female only
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Completed No phase listed Observational

The Effect of Magnesium on Maternal Mood, Cognitive Function, and Birth Experience

NCT02454322
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Magnesium Sulfate
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 5, 2026, 4:28 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mechanism of Thrombocytopenia in Infants

NCT00333333
View directory record Official record
Conditions
Thrombocytopenia, Small for Gestational Age (SGA), Preeclampsia
Interventions
Cord blood
Procedure
Lead sponsor
Christiana Care Health Services
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 12, 2008 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional

Lactation Education Study in Mothers of Very Low Birth Weight Infants

NCT01167517
View directory record Official record
Conditions
Infant, Very Low Birth Weight, Lactation
Interventions
Instructional digital video disc (DVD)
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 28, 2020 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional

Maternal Maneuvers During Prolonged Labor

NCT06636149
View directory record Official record
Conditions
Labor Stage, First, Prolonged Labor
Interventions
Circuit of maternal position changes during labor
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Saint Loius, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 5, 2026, 4:28 PM EDT