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ClinicalTrials.gov public records Last synced Nov 10, 2026, 7:11 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Substance Use, Delinquency
Interventions: Multidimensional Family Therapy (MDFT), Adolescent Residential Treatment; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 13 Years to 17 Years
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2010
U.S. locations: 2
States / cities: Miami, Florida

Conditions: Drug Abuse, Intoxication by Drug, Impairment
Interventions: Placebo, THC, CBD, THC + CBD; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 55 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Methamphetamine, Amphetamine Dependence, Pharmacogenetics, Methamphetamine Dependence, Substance Abuse
Interventions: Bupropion; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Methamphetamine Dependence, Methamphetamine Withdrawal
Interventions: Not listed
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Pain, Chronic, Prescription Drug Abuse (Not Dependent)
Interventions: Not listed
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 275 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 2
States / cities: Gainesville, Florida • Jacksonville, Florida

Conditions: HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage, Alcohol Use, Mental Health, Tobacco Use, HIV Testing
Interventions: Storytelling 4 Empowerment; Device
Lead sponsor: University of Michigan; Other
Eligibility: 16 Years to 21 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Flint, Michigan

Conditions: Marijuana Abuse
Interventions: THC (delta-9 tetrahydrocannabinol), d-amphetamine, oral THC; Drug
Lead sponsor: Wayne State University; Other
Eligibility: 21 Years to 45 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Stimulant Use Disorder
Interventions: Smartphone digital therapeutic system; Device
Lead sponsor: DynamiCare Health; Industry
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance-related Disorders
Interventions: Voucher-Based Reinforcement Therapy; Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Acquired Immune Deficiency Syndrome Virus, Hepatitis C, Drug Abuse
Interventions: MI-based HIV Risk Reduction; Other
Lead sponsor: Michele Staton; Other
Eligibility: 18 Years and older · Female only
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Hazard, Kentucky

Conditions: Alcohol Dependence, Alcohol Abuse
Interventions: Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy, Placebo; Drug · Behavioral
Lead sponsor: Research Foundation for Mental Hygiene, Inc.; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2007
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Abuse, Intravenous
Interventions: Abstinence-contingent wage supplements, Individual Placement and Support (IPS) supported employment; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid-Related Disorders
Interventions: oxycodone and naltrexone; Drug
Lead sponsor: Pain Therapeutics; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
Interventions: Cannabis (THC) (Inhaled) Placebo, Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral); Drug
Lead sponsor: Advanced Brain Monitoring, Inc.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 124 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Craving, Self Efficacy, Affective; Reaction, Substance Abuse
Interventions: CARESS, Isometric Exercise; Behavioral
Lead sponsor: Inova Health Care Services; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Fairfax, Virginia

Conditions: Domestic Violence, Substance Abuse
Interventions: Motivational Enhancement Therapy, Educational information; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older · Male only
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Alcohol Abuse, Drug Abuse
Interventions: Web app; Behavioral
Lead sponsor: Behavior Therapy Associates, LLP; Industry
Eligibility: 21 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Opioid-Related Disorders, Hepatitis C (HCV), Human Immunodeficiency Virus (HIV), Drug Overdose, Substance Abuse, Intravenous Drug Usage, Opiate Substitution Treatment, Sexually Transmitted Diseases
Interventions: Health kiosk; Behavioral
Lead sponsor: April M Young; Other
Eligibility: 18 Years and older
Enrollment: 752 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Opioid Dependency
Interventions: Psychosocial treatment plus Suboxone pharmacotherapy; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 15 Years and older
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Medication Abuse, Harm Reduction
Interventions: Opioid Transitions Clinical Decision Support (CDS); Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 12 Years to 89 Years
Enrollment: 200,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Drug Abuse
Interventions: Computerized Brief Intervention; Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Edgewood, New Mexico

Conditions: Substance-Related Disorders
Interventions: Motivational Enhancement Therapy; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Aggression, Substance-Related Disorders
Interventions: MI-CBT, MI-CBT+CC, E-TAU; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Substance Use Disorders, Drug Abuse, Drug Addiction, Substance Abuse, Drug Use Disorders, Drug Dependence, Substance Addiction
Interventions: Treatment as Usual (TAU), TAU+CBT4CBT; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Richmond, Virginia

Search by objective public record fields.

Family-based and Adolescent Residential Drug Treatment

Evaluation of Oral THC and CBD in Men and Women

Study of Medical Treatment for Methamphetamine Addiction

Characterizing Methamphetamine Withdrawal in Recently Abstinent Methamphetamine Users: A Pilot Study

Linking Epigenomics With Prescription Opioid Abuse and High Impact Musculoskeletal Pain

A Community-University Approach to Preventing HIV

Marijuana Drug Discrimination and Self-Administration

Smartphone Services for Stimulant Use Disorder

Voucher-Based Incentives in a Prevention Setting

Brief Intervention for Rural Women at High Risk for HIV/HCV

Medication and Counseling for Controlled Drinking

The Long-Term Treatment of Drug Addiction and Unemployment

Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse

Cannabis Impairment Detection Application (CIDA)

CARESS: An Investigation of Effects of CARESS

The Men's Domestic Abuse Check-Up Engages Adult Men Concerned About Their Abusive Behavior and Alcohol or Drug Use

A Web App for Patients With Alcohol and Drug Use Problems in Primary Care

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Optimizing Outcomes Using Suboxone for Opiate Dependence

Clinical Decision Support for Safety of Opioid Transitions

Computerized Brief Intervention vs. Delayed Computerized Brief Intervention

Medical Office Intervention for Adolescent Drug Use

Preventing Violence Among Veterans in Substance Use Disorder Treatment

CBT4CBT for Women in Residential Treatment for Substance Use Disorders