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ClinicalTrials.gov public records Last synced Oct 23, 2026, 4:27 AM EDT

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Showing 1–24 of 69 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Mohs Surgery Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Bupivacaine for Post-operative Pain in Mohs

NCT04362566
View directory record Official record
Conditions
Pain, Postoperative, Narcotic Use
Interventions
Bupivacaine, Placebo Saline
Drug · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dermabrasion in Mohs: Split-Scar Trial

NCT07213921
View directory record Official record
Conditions
Wound Heal
Interventions
Dermabrasion
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Not yet recruiting Not applicable Interventional

E-MOHS Trial of TENS and Vibration During Local Anesthesia

NCT07852455
View directory record Official record
Conditions
Pain, Procedural Pain, Local Anesthesia, Mohs Surgery, Skin Cancer
Interventions
Active Vibration:TENS, Sham TENS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
3
States / cities
Maple Grove, Minnesota • Minneapolis, Minnesota • Wyoming, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities

NCT04545476
View directory record Official record
Conditions
Wound Heal
Interventions
Participants in this group will receive the experimental APIS Biomaterial on the Head., Participants in this group will receive the experimental APIS Biomaterial on the Lower Extremities., Standard Secondary Intention Healing on the Head, Standard Secondary Intention Healing on the Lower Extremities
Device · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 12, 2023 · Synced Oct 23, 2026, 4:27 AM EDT
Completed No phase listed Observational

Experience of Non-Melanoma Skin Cancer (NMSC) Mohs Surgery Project

NCT01452984
View directory record Official record
Conditions
Non-Melanoma Skin Cancer
Interventions
Not listed
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2015 · Synced Oct 23, 2026, 4:27 AM EDT
Enrolling by invitation Phase 4 Interventional

Suzetrigine vs Norco-postoperative Mohs Pain

NCT07575230
View directory record Official record
Conditions
Cutaneous Tumors, Mohs Micrographic Surgery
Interventions
Norco 5Mg-325Mg Tablet, Suzetrigine
Drug
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 89 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Buddy Relationships in DermatoloGic Excisions for Skin Cancer

NCT04036344
View directory record Official record
Conditions
Skin Cancer Face, Quality of Life, Surgical Wound, Peer Mentorship
Interventions
Peer Mentorship Program
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of the Subconscious on Mohs Micrographic Surgery

NCT00374062
View directory record Official record
Conditions
Basal Cell Carcinoma, Squamous Cell Carcinoma
Interventions
relaxation therapy 1, relaxation therapy 2, relaxation therapy 3
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
25 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

Investigation of Mohs Surgical Margins Using Two Photon Microscopy

NCT05814900
View directory record Official record
Conditions
Basal Cell Carcinoma
Interventions
Two photon microscopy imaging
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Victor, New York
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Not yet recruiting Phase 4 Interventional

Suzetrigine Versus Standard Analgesia After Skin Cancer Surgery

NCT07843134
View directory record Official record
Conditions
Postoperative Pain, Acute Pain, Skin Cancer, Cutaneous Malignancy, Mohs Surgery
Interventions
Suzetrigine, Acetaminophen Plus Ibuprofen
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
3
States / cities
Maple Grove, Minnesota • Minneapolis, Minnesota • Wyoming, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

3D Printed Models in Mohs Micrographic Surgery

NCT03461965
View directory record Official record
Conditions
Mohs Micrographic Surgery
Interventions
3D printed model, Verbal Counselling
Behavioral
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years to 90 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 21, 2021 · Synced Oct 23, 2026, 4:27 AM EDT
Terminated Not applicable Interventional Results available

Porcine Xenograft Versus Second Intention Healing

NCT03931746
View directory record Official record
Conditions
Wound Healing and Scar Quality Following Mohs Surgery and Excisional Dermatologic Surgery
Interventions
Porcine xenograft
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Bay Shore, New York • Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Oct 23, 2026, 4:27 AM EDT
Completed No phase listed Observational Results available

Comparison of eBX and Mohs Surgery for Treatment of Early-stage Non-melanoma Skin Cancer a Matched Pair Cohort Study.

NCT03024866
View directory record Official record
Conditions
Nonmelanoma Skin Cancer
Interventions
Electronic Brachytherapy
Procedure
Lead sponsor
Xoft, Inc.
Industry
Eligibility
41 Years and older
Enrollment
369 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
4
States / cities
Los Gatos, California • San Diego, California • Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Phase 2 Interventional Results available

Study of EB-001 in Facial Scar Reduction

NCT03346902
View directory record Official record
Conditions
Mohs Surgery
Interventions
EB-001, 0.9% Sodium Chloride Injection
Drug
Lead sponsor
Bonti, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 23, 2026, 4:27 AM EDT
Terminated Not applicable Interventional

Comparison of Elective Lymph Node Treatment Versus Clinical Observation in the Absence of Palpable Lymph Nodes for High Risk Skin Squamous Cell Carcinoma (SCC)

NCT01252329
View directory record Official record
Conditions
High Risk Cutaneous Squamous Cell Carcinoma
Interventions
elective lymph node dissection
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Split Face Study of the Duration of Local Anesthetics

NCT05767749
View directory record Official record
Conditions
Anesthetics, Local
Interventions
lidocaine + epinephrine 1:100,000, Ropivacaine 0.5% Injectable Solution, Bupivacaine 0.5% Injectable Solution
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 23, 2026, 4:27 AM EDT
Completed No phase listed Observational

Reflectance Confocal Microscopy of Wounds During Moh's Surgery: Feasibility Testing of a Mosaicing Algorithm for Intraoperative Imaging of Cancer Margins

NCT01872130
View directory record Official record
Conditions
Basal Cell Carcinoma, Squamous Cell Carcinoma
Interventions
Not listed
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
4
States / cities
Basking Ridge, New Jersey • Harrison, New York • Hauppauge, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2020 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery

NCT06167096
View directory record Official record
Conditions
Skin Cancer, Skin Carcinoma
Interventions
Lavender essential oil, Water
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Not yet recruiting Phase 1 Interventional

Amnion Membrane Powder Mohs Study

NCT07680023
View directory record Official record
Conditions
Wound Heal
Interventions
Amnion Membrane Powder, Standard of Care
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Early Phase 1 Interventional Results available

Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery

NCT04541303
View directory record Official record
Conditions
Postoperative Wound Haemorrhage
Interventions
Tranexamic acid, normal saline
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Study to Determine if Tissue Scored With a Scalpel Results in Any Noticeable Marks

NCT00367042
View directory record Official record
Conditions
Skin Cancer
Interventions
Scalpel for tissue scoring, Surgical marker for tissue marking
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 65 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Oct 23, 2026, 4:27 AM EDT
Recruiting Phase 2 Interventional

MOHs Surgery and Short-Course Radiation Therapy With Structured Follow-Up for Head & Neck Squamous Cell Skin Cancer

NCT06998342
View directory record Official record
Conditions
Cutaneous Squamous Cell Carcinoma (CSCC)
Interventions
Short course radiation, Active Surveillance
Radiation · Other
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 23, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Website Application Based Education and Text Messaging in Improving Skin Wound Care in Patients Undergoing Mohs Surgery

NCT02373722
View directory record Official record
Conditions
Malignant Skin Neoplasm
Interventions
Mohs Surgery, Internet-Based Intervention, Telephone-Based Intervention, Educational Intervention, Exercise Intervention, Petrolatum-Mineral Oil-Lanolin-Ceresin Ointment, Questionnaire Administration, Survey Administration
Procedure · Other · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 3, 2018 · Synced Oct 23, 2026, 4:27 AM EDT
Not yet recruiting Not applicable Interventional

A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer

NCT07032701
View directory record Official record
Conditions
Skin Carcinoma
Interventions
Best Practice, Educational Intervention, Electronic Health Record Review, Follow-Up Care, Medical Device Usage and Evaluation, Negative Pressure Wound Therapy, Photography, Questionnaire Administration
Other · Procedure
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
19 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 23, 2026, 4:27 AM EDT