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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Monitored Anesthesia Care Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Characterize Pharmacokinetics (PK) and Pharmacodynamics (PD) of LUSEDRA® Administered as Continuous Infusion or Bolus Compared With Continuous Infusion of Propofol Injectable Emulsion

NCT01308541
View directory record Official record
Conditions
Monitored Anesthesia Care
Interventions
arm 1, LUSEDRA, Propofol (arm 3)
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Salt Lake City Utah, Utah
Source: ClinicalTrials.gov public record
Updated Nov 2, 2015 · Synced Sep 6, 2026, 4:52 PM EDT
Not listed Not applicable Interventional

Hand Holding During Light Sedation for Minimally Invasive Spine Surgery Improves Outcomes

NCT05058079
View directory record Official record
Conditions
Spine, Minimally Invasive
Interventions
Intraoperative Hand Held
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Phase 3 Interventional

A Safety and Efficacy Study of Dexmedetomidine in Patients Requiring Sedation During Monitored Anesthesia Care (MAC)

NCT00398827
View directory record Official record
Conditions
Anesthesia, Surgical Procedures, Elective
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Hospira, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
27
States / cities
Birmingham, Alabama • Loma Linda, California • Miami, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2015 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prevention and Treatment of Laryngospasm and Hypoxemia Based on Risk Factors in Adult Outpatients Undergoing EGD

NCT04159116
View directory record Official record
Conditions
Laryngospasm, Hypoxemia
Interventions
Prophylactic suctioning when clinically indicated
Other
Lead sponsor
Envision Healthcare Scientific Intelligence, Inc.
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Moon Township, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Sep 6, 2026, 4:52 PM EDT
Recruiting Not applicable Interventional

Prospective Study to Evaluate High Flow Nasal Cannula With Monitored Anesthesia Care During EBUS Bronchoscopy

NCT05203328
View directory record Official record
Conditions
Lung Cancer
Interventions
Vapotherm, Regular nasal canula
Device
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Phase 1 Interventional

A Study to Assess the Transfer of Fospropofol and Its Active Metabolite, Propofol, to Breast Milk Following Administration of LUSEDRA to Lactating Women Undergoing a Needed Procedure

NCT01309984
View directory record Official record
Conditions
Lactating Women
Interventions
Lusedra, Propofol
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 2, 2015 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Not applicable Interventional Results available

Use of Stable Airway Management Device in Monitored Anesthesia Care

NCT05087979
View directory record Official record
Conditions
Anesthesia
Interventions
Stable airway management (SAM) device
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 7, 2024 · Synced Sep 6, 2026, 4:52 PM EDT
Recruiting No phase listed Observational

The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

NCT07022951
View directory record Official record
Conditions
Anesthesia, Sedation, Monitored Anesthesia Care, Procedure, Surgery, Day, Surgery, Surgery Scheduled, Fasting Before Operation, Aspiration; Gastric Contents, Anesthesia
Interventions
Preoperative fasting
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
1,200,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 6, 2026, 4:52 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Safety of Driving After Minor Surgery With Monitored Anesthesia Care

NCT00577200
View directory record Official record
Conditions
Minor Surgical Procedures With Monitored Anesthesia Care, Driving Performance After Minor Ambulatory Surgery
Interventions
Midazolam, Sufentanil, Propofol
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years to 70 Years
Enrollment
625 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Phase 2 Interventional Results available

Intraoperative Aromatherapy Versus Placebo for Port-a-Cath Placement Under Monitored Anesthesia Care. A Randomized Controlled Trial

NCT05328973
View directory record Official record
Conditions
Cancer Pain
Interventions
ELEQUIL
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2024 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy

NCT03369197
View directory record Official record
Conditions
Hypoxia, Endoscopy, Anesthesia Morbidity
Interventions
Nasal Mask, Control: Nasal Cannula
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study

NCT06506669
View directory record Official record
Conditions
Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
Interventions
Oral sedation, Placebo
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Phase 4 Interventional Results available

A Dose-ranging Study to Evaluate the Safety and Efficacy of LUSEDRA (Fospropofol Disodium) as an Intravenous Sedative for Diagnostic or Therapeutic Colonoscopy in Adult Special Populations

NCT01127438
View directory record Official record
Conditions
Sedation
Interventions
fospropofol disodium Subgroup 1 Lower Dose, fospropofol disodium Subgroup 1 Approved Dose, fospropofol disodium Subgroup 2 Lower Dose, fospropofol disodium Subgroup 2 Approved Dose, fospropofol disodium Subgroup 3 Lower Dose, fospropofol disodium Subgroup 3 Approved Dose
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
23
States / cities
Phoenix, Arizona • Baldwin Park, California • San Diego, California + 20 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2013 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Phase 4 Interventional

Dexmedetomidine vs. Propofol for Cataract Surgery

NCT00786370
View directory record Official record
Conditions
Cataract
Interventions
dexmedetomidine, Propofol, Dexemedetomidine
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 9, 2012 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Not applicable Interventional Results available

Anti-Snoring Appliances and Airway Manipulation in Patients Undergoing Anesthetic Sedation

NCT05748626
View directory record Official record
Conditions
Airway Obstruction, Snoring, Sedation Complication
Interventions
Anti-snoring device, No anti -snoring device during their procedure.
Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Sep 6, 2026, 4:52 PM EDT
Completed No phase listed Observational

A New Flexible Extended-Length Pharyngeal Airway for Deep Sedation

NCT04419883
View directory record Official record
Conditions
Upper Airway Obstruction
Interventions
McMurray Enhanced Airway
Device
Lead sponsor
McMurray Medical Group, LLC
Industry
Eligibility
18 Years and older
Enrollment
86 participants
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Sep 6, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Monitored Anesthesia Care vs. General Anesthesia for Transcatheter Aortic Valve Replacement

NCT04107038
View directory record Official record
Conditions
Transcatheter Aortic Valve Replacement
Interventions
General Endotracheal Anesthesia, Monitored anesthesia care
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 6, 2026, 4:52 PM EDT