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ClinicalTrials.gov public records Last synced May 22, 2026, 1:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 108 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Mood Disorder NOS Clear all
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Aspirin, N-acetyl-cysteine (NAC), Sugar Pill
Drug · Dietary Supplement
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 29, 2018 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Schizophreniform Disorder, Schizoaffective Disorder, Psychosis, Depressive Disorder, Major, Bipolar Disorder
Interventions
Ziprasidone
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced May 22, 2026, 1:37 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Mood Disorder, Psychotic
Interventions
mobile Social Interaction Therapy by Exposure (mSITE)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced May 22, 2026, 1:37 AM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Bipolar Disorder, Depression, Mood Disorder
Interventions
External Facilitation, External + Internal Facilitation
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 99 Years
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Denver, Colorado • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Depression
Interventions
Sertraline, Placebo, BupropionXL
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
296 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
4
States / cities
Boston, Massachusetts • Ann Arbor, Michigan • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 25, 2018 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Clozapine
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced May 22, 2026, 1:37 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Depression
Interventions
Growth Mindset
Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
11 Years to 25 Years
Enrollment
4,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Mood Disorder, Anxiety Disorders
Interventions
Low dose NPY, High dose NPY, Placebo
Drug
Lead sponsor
Dennis Charney
Other
Eligibility
25 Years to 45 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Bipolar Disorder, Mood Disorder, Unipolar Depression
Interventions
Magstim Super Rapid Magnetic Stimulator, Cadwell MES-10
Device
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 90 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 12, 2006 · Synced May 22, 2026, 1:37 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Mood Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
40 Years to 65 Years · Female only
Enrollment
1,158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1989
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced May 22, 2026, 1:37 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Psychosis, Schizophrenia, Schizoaffective Disorder, Psychosis Nos/Other, Bipolar Disorder
Interventions
Care Coordination, Individual Peer Support, Digital Outreach, Cognitive Remediation, Multi-Family Group Therapy
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
Not listed
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Cambridge, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Depression
Interventions
Thymatron, Magstim Theta
Device
Lead sponsor
Sarah Lisanby
Other
Eligibility
18 Years to 90 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Durham, North Carolina • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2015 · Synced May 22, 2026, 1:37 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Depression NOS, Major Depressive Disorder, Anxiety NOS
Interventions
Kirtan Kriya meditation, Relaxation
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
45 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2016 · Synced May 22, 2026, 1:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Depression and Suicide, Mood Disorders, Other Perinatal Conditions
Interventions
Not listed
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older · Female only
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
3
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced May 22, 2026, 1:37 AM EDT
Terminated Phase 2 Interventional Results available
View directory record Official record
Conditions
Major Depressive Disorder With Suicidal Ideation With Intent
Interventions
MIJ821 Intravenous Injection, Placebo Intravenous Injection
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
6
States / cities
Birmingham, Alabama • Farmington, Connecticut • Oakland Park, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Mood Disorders
Interventions
Lamotrigine
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
18
States / cities
San Diego, California • Santa Ana, California • Jacksonville, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2016 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 1Phase 2 Interventional Results available
View directory record Official record
Conditions
Major Depression, Dysthymia, Depressive Disorder Not Otherwise Specified
Interventions
Fluoxetine, Imipramine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Heart Failure, Systolic, Depression, Cardiovascular Disease
Interventions
Collaborative Care for Heart Failure, Collaborative Care for Depression
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
756 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced May 22, 2026, 1:37 AM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Depression Disorders
Interventions
Kandoo
Device
Lead sponsor
Child Mind Institute
Other
Eligibility
13 Years to 25 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced May 22, 2026, 1:37 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Bipolar Disorder, Depression
Interventions
Chronic Care Model for Mood Disorders
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Palo Alto, California • San Francisco, California • Denver, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2012 · Synced May 22, 2026, 1:37 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Anxiety in Pregnancy, Mood Disorder Due to Specified Medical Condition
Interventions
BE-OR: Brief Intervention to the Operating Room, Interaction: Facetime with Clinical Provider
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Dysthymic Disorder, Depressive Disorder NOS
Interventions
Duloxetine (Cymbalta)
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
20 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2017 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Bipolar Disorder I or II
Interventions
Tranylcypromine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced May 22, 2026, 1:37 AM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Mood Disorder, Mental Disorder Diagnosed in Childhood, Attention Deficit and Disruptive Behavior Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Add-on citalopram following optimized methylphenidate, Add-on placebo following optimized methylphenidate
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
7 Years to 17 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced May 22, 2026, 1:37 AM EDT