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ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:17 PM EST

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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Necrotising Enterocolitis Neonatal Clear all

Conditions: Necrotizing Enterocolitis, Bronchopulmonary Dysplasia, Growth Failure
Interventions: Not listed
Lead sponsor: University of California, Davis; Other
Eligibility: Up to 33 Weeks
Enrollment: 300 participants
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Short Bowel Syndrome
Interventions: Distraction Enterogenesis in Adult Patients with Short Bowel Syndrome; Device
Lead sponsor: Eclipse Regenesis, Inc.; Other
Eligibility: 3 Months to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 5
States / cities: Palo Alto, California • San Francisco, California • Washington D.C., District of Columbia + 2 more

Conditions: Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis, Motor Skills Disorders
Interventions: delayed cord clamping; Procedure
Lead sponsor: University of Rhode Island; Other
Eligibility: Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
Interventions: Laparotomy, Drainage; Procedure
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: Up to 8 Weeks
Enrollment: 529 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 22
States / cities: Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more

Conditions: Patent Ductus Arteriosus, Surgery, Necrotizing Enterocolitis, Intestinal Perforation
Interventions: pharmacologic treatment of the PDA, no pharmacologic treatment of the PDA, NSAID; Other · Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 5 Days to 14 Days
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 13
States / cities: San Diego, California • San Francisco, California • San Jose, California + 9 more

Conditions: Prematurity, Necrotizing Enterocolitis
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: Up to 1 Year
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2020
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Cholestasis, Jaundice, Obstructive
Interventions: SMOFlipid; Drug
Lead sponsor: University of Florida; Other
Eligibility: 23 Weeks to 1 Year
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Necrotizing Enterocolitis of Newborn, Bowel Ischemic
Interventions: Sulfur hexafluoride lipid-type A microspheres; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 0 Years to 18 Months
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Premature Newborn, Necrotizing Enterocolitis
Interventions: Citrulline samples; Diagnostic Test
Lead sponsor: University of Miami; Other
Eligibility: Not listed
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Sepsis, Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Retinopathy of Prematurity, Systemic Inflammatory Response Syndrome
Interventions: Parenteral cysteine-HCl supplementation, Placebo - added premasol; Dietary Supplement
Lead sponsor: University of California, Los Angeles; Other
Eligibility: Up to 30 Days
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Serious Systemic Infections, Necrotizing Enterocolitis
Interventions: Metronidazole; Drug
Lead sponsor: Michael Cohen-Wolkowiez; Other
Eligibility: Up to 90 Days
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 3
States / cities: Orange, California • Wichita, Kansas • Durham, North Carolina

Conditions: Cholestasis, Prematurity, Gastroschisis, Intestinal Atresia, Necrotizing Enterocolitis
Interventions: Parenteral Nutrition; Dietary Supplement
Lead sponsor: University of Miami; Other
Eligibility: Up to 7 Days
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Anemia, Neonatal, Necrotizing Enterocolitis, Dysbiosis
Interventions: Not listed
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 7 Days to 30 Days
Enrollment: 57 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Anemia
Interventions: Inhaled Nitric Oxide, Placebo; Drug
Lead sponsor: New York Medical College; Other
Eligibility: 2 Weeks and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 4
States / cities: Springfield, Massachusetts • Stony Brook, New York • Valhalla, New York + 1 more

Conditions: Necrotizing Enterocolitis
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 1 Day to 2 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2003
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Enterocolitis, Necrotizing, Congenital Heart Disease
Interventions: Bowel Ultrasound; Device
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: Up to 6 Months
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Necrotizing Enterocolitis (NEC)
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: Up to 1 Hour
Enrollment: 388 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2026
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Infant, Very Low Birth Weight, Infant, Premature, Ductus Arteriosus, Patent
Interventions: Indomethacin, Placebo; Drug
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: 2 Hours to 6 Hours
Enrollment: 1,202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1993 – 2001
U.S. locations: 9
States / cities: Birmingham, Alabama • Palo Alto, California • Miami, Florida + 6 more

Conditions: NEC, Necrotizing Enterocolitis, Intestinal Disease, Human Development
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Up to 2 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2034
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Necrotizing Enterocolitis
Interventions: Not listed
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: Up to 7 Days
Enrollment: 450 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Patent Ductus Arteriosus
Interventions: indomethacin (two different dosing regimens); Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: Up to 48 Hours
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 3
States / cities: Davis, California • Chicago, Illinois • Providence, Rhode Island

Conditions: Anemia of Prematurity, Necrotizing Enterocolitis
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: Up to 12 Weeks
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 3
States / cities: Murray, Utah • Salt Lake City, Utah

Conditions: Neonatal Infection, Neonatal Necrotizing Enterocolitis
Interventions: Gloves; Other
Lead sponsor: University of Virginia; Other
Eligibility: Up to 8 Days
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Total Parenteral Nutrition, Necrotizing Enterocolitis of Newborn
Interventions: Similac Probiotic Tri-Blend; Dietary Supplement
Lead sponsor: Pediatrix; Other
Eligibility: Not listed
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Mesa, Arizona • Phoenix, Arizona

Search by objective public record fields.

A Cohort Study of the Intestinal Microbiota of Premature Infants

A Feasibility Study to Evaluate Safety and Probable Benefit of the Eclipse XL1 System for Distraction Enterogenesis in Adult and Pediatric Patients With Short Bowel Syndrome

Effects of Delayed Cord Clamping in Very Low Birth Weight Infants

Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis

Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus

Neutrophil Extracellular Trap Formation in Newborn Infants at Risk for Inflammatory Syndromes

SMOFlipid to Lessen the Severity of Neonatal Cholestasis

CEUS Evaluation of Bowel Perfusion in Necrotizing Enterocolitis

Defining Normal Citrulline Levels as a Diagnostic Tool for Screening of Gastrointestinal Disease in Premature Infants

Cysteine Supplementation in Critically Ill Neonates

Metronidazole Pharmacokinetics (PK) in Premature Infants

Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in Infants

Alteration of Stool Microbiota in Preterm Infants With Anemia

Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNO

Necrotizing Enterocolitis (NEC) Surgical Database

Utility of Bowel Ultrasound in Diagnosing Necrotizing Eneterocolitis in Congenital Heart Disease

NETs: Protection or Harm in Neonatal Inflammation or Infection

Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)

Study of Normal Intestinal Development and Disease in Premature and Term Neonates

Early Predictors of Necrotizing Enterocolitis in Neonates

Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus

Transfusion-related Inflammatory Cytokine and Neutrophil Extracellular Trap Quantification in Neonates

Study to Determine if Gloving in Addition to Hand Hygiene Will Prevent Invasive Infections and Necrotizing Enterocolitis

Probiotics/TPN in the NICU