- Conditions
- Enterocolitis, Necrotizing, Congenital Heart Disease
- Interventions
- Bowel Ultrasound
- Device
- Lead sponsor
- Children's Mercy Hospital Kansas City
- Other
- Eligibility
- Up to 6 Months
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Kansas City, Missouri
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Necrotizing Enterocolitis of Newborn, Bowel Ischemic
- Interventions
- Sulfur hexafluoride lipid-type A microspheres
- Drug
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 0 Years to 18 Months
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Premature Newborn, Necrotizing Enterocolitis
- Interventions
- Citrulline samples
- Diagnostic Test
- Lead sponsor
- University of Miami
- Other
- Eligibility
- Not listed
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2017
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Infant, Very Low Birth Weight, Infant, Premature, Ductus Arteriosus, Patent
- Interventions
- Indomethacin, Placebo
- Drug
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- 2 Hours to 6 Hours
- Enrollment
- 1,202 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1993 – 2001
- U.S. locations
- 9
- States / cities
- Birmingham, Alabama • Palo Alto, California • Miami, Florida + 6 more
- Conditions
- Necrotizing Enterocolitis
- Interventions
- Not listed
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- Up to 7 Days
- Enrollment
- 450 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2026
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Congenital Heart Disease, Prematurity, Necrotizing Enterocolitis
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- Up to 1 Month
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Infection, Enterocolitis, Necrotizing, Ventilator-associated Pneumonia
- Interventions
- oropharyngeal mother's milk, oropharyngeal sterile water
- Other
- Lead sponsor
- Endeavor Health
- Other
- Eligibility
- 1 Day to 4 Days
- Enrollment
- 260 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 5
- States / cities
- Miami, Florida • Evanston, Illinois • Park Ridge, Illinois + 2 more
- Conditions
- Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
- Interventions
- Ampicillin, Gentamycin, Normal saline
- Drug
- Lead sponsor
- Michael Morowitz
- Other
- Eligibility
- Up to 4 Hours
- Enrollment
- 359 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 14
- States / cities
- Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more
- Conditions
- Total Parenteral Nutrition, Necrotizing Enterocolitis of Newborn
- Interventions
- Similac Probiotic Tri-Blend
- Dietary Supplement
- Lead sponsor
- Pediatrix
- Other
- Eligibility
- Not listed
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 2
- States / cities
- Mesa, Arizona • Phoenix, Arizona
- Conditions
- Cholestasis, Jaundice, Obstructive
- Interventions
- SMOFlipid
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 23 Weeks to 1 Year
- Enrollment
- 2 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Patent Ductus Arteriosus
- Interventions
- indomethacin (two different dosing regimens)
- Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- Up to 48 Hours
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 3
- States / cities
- Davis, California • Chicago, Illinois • Providence, Rhode Island
- Conditions
- Premature Birth of Newborn, Enterocolitis, Necrotizing
- Interventions
- Ampicillin, Gentamicins, Placebo
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Up to 6 Hours
- Enrollment
- 27 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
- Interventions
- Laparotomy, Drainage
- Procedure
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 8 Weeks
- Enrollment
- 529 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2019
- U.S. locations
- 22
- States / cities
- Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more
- Conditions
- Infant, Premature, Diseases, Hypoxia, Necrotizing Enterocolitis
- Interventions
- Near Infrared Spectroscopy
- Device
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- Up to 3 Weeks
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Necrotizing Enterocolitis (NEC)
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- Up to 1 Hour
- Enrollment
- 388 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2026
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Anemia
- Interventions
- Inhaled Nitric Oxide, Placebo
- Drug
- Lead sponsor
- New York Medical College
- Other
- Eligibility
- 2 Weeks and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 4
- States / cities
- Springfield, Massachusetts • Stony Brook, New York • Valhalla, New York + 1 more
- Conditions
- NEC, Necrotizing Enterocolitis, Intestinal Disease, Human Development
- Interventions
- Not listed
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- Up to 2 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2034
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Transfusions
- Interventions
- NPO, Control group: continue feedings
- Other
- Lead sponsor
- Christiana Care Health Services
- Other
- Eligibility
- 3 Days to 6 Months
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Necrotizing Enterocolitis, Digestive System Abnormalities, Cholestasis
- Interventions
- remove Mn from PN if evidence of increased brain Mn on MRI
- Dietary Supplement
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 30 Days to 12 Months
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Serious Systemic Infections, Necrotizing Enterocolitis
- Interventions
- Metronidazole
- Drug
- Lead sponsor
- Michael Cohen-Wolkowiez
- Other
- Eligibility
- Up to 90 Days
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011
- U.S. locations
- 3
- States / cities
- Orange, California • Wichita, Kansas • Durham, North Carolina
- Conditions
- Sepsis, Necrotising Enterocolitis Neonatal
- Interventions
- No Intervention: Observational Cohort
- Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- Not listed
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Anemia of Prematurity, Necrotizing Enterocolitis
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- Up to 12 Weeks
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 3
- States / cities
- Murray, Utah • Salt Lake City, Utah
- Conditions
- Necrotizing Enterocolitis, Bronchopulmonary Dysplasia, Growth Failure
- Interventions
- Not listed
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- Up to 33 Weeks
- Enrollment
- 300 participants
- Timeline
- 2018 – 2027
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Parenteral Nutrition, Necrotizing Enterocolitis, Digestive System Abnormalities, Cholestasis
- Interventions
- Remove Mn from PN if evidence of increased brain Mn on MRI
- Dietary Supplement
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 30 Days to 6 Years
- Enrollment
- 122 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2010
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee