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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Necrotizing Pancreatitis Clear all
Completed No phase listed Observational

A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes

NCT06227871
View directory record Official record
Conditions
Pancreatic Trauma, Pancreatic Duct Injury, Pancreas Necrosis, Pancreas Cyst, Pancreas; Fistula, Pancreas Abscess, Intra-Abdominal Abscess, Anastomotic Leak, Pancreas Injury
Interventions
Exploratory laparotomy
Procedure
Lead sponsor
Kern Medical Center
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2024 · Synced Jul 21, 2026, 3:23 PM EDT
Recruiting Not applicable Interventional

Necrosectomy With Cryotechnology for Accelerated Removal

NCT06553651
View directory record Official record
Conditions
Pancreatic Necrosis, Acute Pancreatitis, Acute Pancreatic Necrosis, Necrosis, Necrosis Pancreas, Walled-Off Pancreatic Necrosis
Interventions
Cryotechnology Necrosectomy Procedure
Device
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 21, 2026, 3:23 PM EDT
Not listed Not applicable Interventional

Randomized Trial of Immediate Endoscopic Necrosectomy vs. Step-up Endoscopic Interventions in Necrotizing Pancreatitis

NCT05043415
View directory record Official record
Conditions
Pancreatitis,Acute Necrotizing
Interventions
Immediate endoscopic necrosectomy, Step-up endoscopic interventions
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Jul 21, 2026, 3:23 PM EDT
Recruiting No phase listed Observational

Registry of Patients Undergoing Endoscopic Management of Pancreatic Fluid Collections

NCT06179459
View directory record Official record
Conditions
Acute Pancreatitis, Pancreatic Pseudocyst, Pancreatic Necrosis
Interventions
Endoscopic management of pancreatic fluid collections
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Not applicable Interventional

Minimally Invasive Surgery vs. Endoscopy Randomized (MISER) Trial for Necrotizing Pancreatitis

NCT02084537
View directory record Official record
Conditions
Necrosis of Pancreas, Infected Pancreatic Necrosis
Interventions
Endoscopic treatment, Minimally invasive surgical necrosectomy
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2019 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Early Phase 1 Interventional Results available

Pentoxifylline Treatment of Acute Pancreatitis

NCT01292005
View directory record Official record
Conditions
Acute Pancreatitis
Interventions
Pentoxifylline, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Jul 21, 2026, 3:23 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Imaging Modalities for Pancreatic Collections

NCT03556501
View directory record Official record
Conditions
Pancreas Necrosis
Interventions
Endoscopy
Diagnostic Test
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2023 · Synced Jul 21, 2026, 3:23 PM EDT
Recruiting No phase listed Observational

DEciphering CIrculating SIgnatures Of Infected Pancreatic Necrosis

NCT06899087
View directory record Official record
Conditions
Acute Pancreatitis
Interventions
not interventional
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Not applicable Interventional Results available

EndoRotor DEN (Direct Endoscopic Necrosectomy)Trial

NCT03694210
View directory record Official record
Conditions
Acute Pancreatic Necrosis, Acute Pancreatitis, Necrotizing Pancreatitis
Interventions
EndoRotor Therapy
Device
Lead sponsor
Interscope, Inc.
Industry
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
7
States / cities
Little Rock, Arkansas • Palo Alto, California • San Francisco, California + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Phase 4 Interventional

A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died

NCT00061438
View directory record Official record
Conditions
Pancreatitis, Acute Necrotizing
Interventions
meropenem
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
9
States / cities
San Francisco, California • Tampa, Florida • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Jul 21, 2026, 3:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Molecular Analysis of Microbial DNA in Infected Necrotizing Pancreatitis

NCT01815489
View directory record Official record
Conditions
Necrotizing Pancreatitis
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Jul 21, 2026, 3:23 PM EDT
Completed No phase listed Observational

Rad Predictors for WON

NCT03801070
View directory record Official record
Conditions
Walled Off Pancreatic Necrosis (WON)
Interventions
endoscopic drainage of walled off pancreatic necrosis
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
19 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Not applicable Interventional

Comparison of FCSEMS and Plastic Stents

NCT02685865
View directory record Official record
Conditions
Infected Pancreatic Necrosis, Acute Pancreatic Fluid Collection, Pancreatic and Peripancreatic Necrosis, Pancreatic Collection, Symptomatic Pancreatic Necrosis
Interventions
FCSEM Stent, Plastic Stent
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2019 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Not applicable Interventional

Videoendoscopic Drainage of Infected Pancreatic Collections

NCT00061269
View directory record Official record
Conditions
Pancreatitis, Acute Necrotizing
Interventions
Videoscopic-Assisted Retroperitoneal Debridement (VARD)
Procedure
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
5
States / cities
Portland, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Not applicable Interventional

Endoscopic Necrosectomy Versus Step-up Endoscopic Intervention

NCT04113499
View directory record Official record
Conditions
Pancreatic Necrosis, Necrosis Pancreas
Interventions
Direct Endoscopic Intervention, Step-up Endoscopic Intervention
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Jul 21, 2026, 3:23 PM EDT
Completed No phase listed Observational

ABTHERA ADVANCE™ Use Without Wittman Patch

NCT04986943
View directory record Official record
Conditions
Necrotizing Pancreatitis
Interventions
Using ABTHERA Advance without a Wittmann Patch
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
22 Years and older
Enrollment
3 participants
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Not applicable Interventional Results available

AXIOS Lumen Apposing Metal Stent for Walled Off Necrosis Drainage IDE Study

NCT03525808
View directory record Official record
Conditions
Walled Off Pancreatic Necrosis
Interventions
AXIOS
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
5
States / cities
Aurora, Colorado • Atlanta, Georgia • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2021 · Synced Jul 21, 2026, 3:23 PM EDT
Recruiting Not applicable Interventional

Strategic Timing of Endoscopic Interventions in Infected Necrotizing Pancreatitis

NCT07406698
View directory record Official record
Conditions
Pancreatitis, Acute Necrotizing
Interventions
EUS-guided transluminal drainage of necrotic collection
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 21, 2026, 3:23 PM EDT
Completed No phase listed Observational

Patient-reported Outcome Scale in Acute Pancreatitis

NCT03650062
View directory record Official record
Conditions
Acute Pancreatitis
Interventions
Not listed
Lead sponsor
Enrique de-Madaria
Other
Eligibility
18 Years to 79 Years
Enrollment
525 participants
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Jul 21, 2026, 3:23 PM EDT
Completed Not applicable Interventional

Pancreatic Duct Stent for Acute Necrotizing Pancreatitis

NCT03115918
View directory record Official record
Conditions
Necrotizing Pancreatitis, Walled Off Necrosis
Interventions
Pancreatic Duct Stent Placement, No Pancreatic Duct Stent Placement
Device · Other
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Jul 21, 2026, 3:23 PM EDT
Terminated Not applicable Interventional Results available

Study of a Lumen- Apposing, Covered, Self-Expanding Metal Stent (Axios™) Versus Multiple Double Pigtail Stents

NCT02673541
View directory record Official record
Conditions
Pancreatic Necrosis
Interventions
AXIOS™ stent, Double Pigtail Stents
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 5, 2020 · Synced Jul 21, 2026, 3:23 PM EDT