- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis, Autism, Autistic Disorder, Bacterial Meningitis, Bacterial Septicemia, Benzodiazepine, Bipolar Disorder, Bone and Joint Infections, Central Nervous System Infections, Convulsions, Cytomegalovirus Retinitis, Early-onset Schizophrenia Spectrum Disorders, Epilepsy, General Anesthesia, Gynecologic Infections, Herpes Simplex Virus, Infantile Hemangioma, Infection, Inflammation, Inflammatory Conditions, Intra-abdominal Infections, Lower Respiratory Tract Infections, Migraines, Pain, Pneumonia, Schizophrenia, Sedation, Seizures, Skeletal Muscle Spasms, Skin and Skin-structure Infections, Treatment-resistant Schizophrenia, Urinary Tract Infections, Withdrawal, Sepsis, Gram-negative Infection, Bradycardia, Cardiac Arrest, Cardiac Arrhythmia, Staphylococcal Infections, Nosocomial Pneumonia, Neuromuscular Blockade, Methicillin Resistant Staphylococcus Aureus, Endocarditis, Neutropenia, Headache, Fibrinolytic Bleeding, Pulmonary Arterial Hypertension, CMV Retinitis, Hypertension, Chronic Kidney Diseases, Hyperaldosteronism, Hypokalemia, Heart Failure, Hemophilia, Heavy Menstrual Bleeding, Insomnia
- Interventions
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Drug
- Lead sponsor
- Daniel Benjamin
- Other
- Eligibility
- Up to 21 Years
- Enrollment
- 3,520 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 43
- States / cities
- Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more
Search Results
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Showing 25–48
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- Conditions
- Infant, Newborn, Diseases, Early Onset Neonatal Sepsis, Early-Onset Meningitis
- Interventions
- Not listed
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 72 Hours
- Enrollment
- 570 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 20
- States / cities
- Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 16 more
- Conditions
- Catheter-associated Bloodstream Infections (CLABSI)
- Interventions
- Sample collection
- Other
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 1 Day to 3 Weeks
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Cytomegalovirus Infections, HIV Infections
- Interventions
- Valganciclovir
- Drug
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 13 Years and older
- Enrollment
- 350 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2006
- U.S. locations
- 56
- States / cities
- Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 33 more
- Conditions
- Necrotizing Enterocolitis, Necrotizing Enterocolitis of Newborn, Sepsis Newborn, Cows Milk Allergy
- Interventions
- Survey investigating Infant formula feeding in newborns
- Dietary Supplement
- Lead sponsor
- Neuroganics LLC
- Industry
- Eligibility
- 1 Day to 2 Years
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Northglenn, Colorado
- Conditions
- Sepsis, Septicemia, Sepsis Syndrome, Shock, Septic, Community Acquired Pneumonia
- Interventions
- Not listed
- Lead sponsor
- National Center for Genome Resources
- Other
- Eligibility
- 6 Years and older
- Enrollment
- 1,200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2010
- U.S. locations
- 3
- States / cities
- Detroit, Michigan • Durham, North Carolina
- Conditions
- Acute Kidney Injury, Acute Kidney Injury Due to Sepsis, Neonatal Sepsis
- Interventions
- Renal Angina Index (RAI)
- Other
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- Other
- Eligibility
- Up to 25 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Line Insertion Site, Central Line-associated Bloodstream Infection (CLABSI)
- Interventions
- Povidone-Iodine, Chlorhexidine gluconate, Pluronic Cream, control
- Drug · Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- Up to 7 Days
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Sepsis, Congenital Diaphragmatic Hernia, Neonatal Cardiopulmonary Failure
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- Up to 2 Months
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 2
- States / cities
- Salt Lake City, Utah
- Conditions
- Central Line Bloodstream Infections
- Interventions
- Silver Alginate
- Device
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 1 Day to 3 Weeks
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2015
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Bronchopulmonary Dysplasia, Respiration, Artificial, Respiratory Distress Syndrome, Newborn, Sepsis
- Interventions
- Vitamin A, Sham Procedure
- Drug · Other
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- 24 Hours to 96 Hours
- Enrollment
- 807 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 1999
- U.S. locations
- 11
- States / cities
- Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 8 more
- Conditions
- Infection, Enterocolitis, Necrotizing, Ventilator-associated Pneumonia
- Interventions
- oropharyngeal mother's milk, oropharyngeal sterile water
- Other
- Lead sponsor
- Endeavor Health
- Other
- Eligibility
- 1 Day to 4 Days
- Enrollment
- 260 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 5
- States / cities
- Miami, Florida • Evanston, Illinois • Park Ridge, Illinois + 2 more
- Conditions
- Hypothermia
- Interventions
- placement of plastic cap during delivery room stabilization, placement of routine cap during delivery room stabilization
- Other
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- Up to 1 Hour
- Enrollment
- 260 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Group B Streptococcus Neonatal Sepsis
- Interventions
- Not listed
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- Started 2006
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Complication of Prematurity, Immunologic Deficiency Syndromes
- Interventions
- Adjuvant, Blood Collection
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- Up to 55 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Serious Systemic Infections, Necrotizing Enterocolitis
- Interventions
- Metronidazole
- Drug
- Lead sponsor
- Michael Cohen-Wolkowiez
- Other
- Eligibility
- Up to 90 Days
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011
- U.S. locations
- 3
- States / cities
- Orange, California • Wichita, Kansas • Durham, North Carolina
- Conditions
- Neonatal SEPSIS
- Interventions
- Blood Collection Preterm, Blood Collection Term, Adult Blood collection
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 23 Weeks to 42 Weeks
- Enrollment
- 293 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2026
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Sepsis
- Interventions
- piperacillin-tazobactam
- Drug
- Lead sponsor
- Phillip Brian Smith
- Other
- Eligibility
- Up to 60 Days
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 4
- States / cities
- Indianapolis, Indiana • Wichita, Kansas • Kansas City, Missouri + 1 more
- Conditions
- Infection Associated With Catheter, Bacteremia, Sepsis
- Interventions
- Ethanol lock, Heparinized saline
- Drug
- Lead sponsor
- East Carolina University
- Other
- Eligibility
- Up to 32 Weeks
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2010
- U.S. locations
- 1
- States / cities
- Greenville, North Carolina
- Conditions
- Neonatal Staphylococcal Sepsis
- Interventions
- Pagibaximab (formerly BSYX-A110)
- Drug
- Lead sponsor
- Biosynexus Incorporated
- Industry
- Eligibility
- 3 Days to 7 Days
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2003
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Enterocolitis, Necrotizing, Bacteremia, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Periventricular Leukomalacia, Chronic Lung Disease, Ileal Perforation
- Interventions
- Antibiotic, Gastric fluid, Breast milk, Stool samples, Antibiotics
- Drug · Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 23 Weeks to 33 Weeks
- Enrollment
- 98 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Early Onset Sepsis, Preterm Neonates, NICU, Ampicillin, Safety and Pharmacokinetics
- Interventions
- Ampicillin prescribed by provider per standard of care for evaluation of early onset sepsis
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 0 Days to 7 Days
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Necrotizing Enterocolitis, Sepsis
- Interventions
- Fortified Pasteurized Donor Human Milk supplement, Preterm Formula supplement
- Behavioral
- Lead sponsor
- National Center for Research Resources (NCRR)
- NIH
- Eligibility
- 0 Years to 96 Hours
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1997
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Congenital Heart Disease, Viremia, Virus Diseases, Enterovirus, Enterovirus Infections, Heart Defects, Congenital, Heart Diseases, Prenatal Infection, Diabetes, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Diabetes Mellitus, Pregnancy in Diabetic, Pregnancy Complications, Prenatal
- Interventions
- Stool and Blood Specimen Collection, Follow-up Medical Record Review
- Other
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Enrollment
- 114 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 2
- States / cities
- St Louis, Missouri