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ClinicalTrials.gov public records Last synced Jul 23, 2026, 2:45 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Alzheimer Disease, Amyloid Beta-Peptides, Risk Assessment, Education, Neuropsychological Tests, Neuroimaging
Interventions
Alzheimer's Disease Risk Disclosure, Amyloid Brain Imaging and Alzheimer's Disease Risk Disclosure
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years to 80 Years
Enrollment
315 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
4
States / cities
Boston, Massachusetts • Ann Arbor, Michigan • Durham, North Carolina + 1 more
Completed No phase listed Observational Accepts healthy volunteers

DETECT and Retinal Outcomes in Hypertension

NCT01815567
Conditions
Hypertension, Retinal Disorder, Cognitive Impairment
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Suspended Not applicable Interventional Accepts healthy volunteers

Development of Novel Measures for Alzheimer's Disease Prevention Trials

NCT03900273
Conditions
Healthy Participants
Interventions
No Practice Effects (NPE) cognitive battery, and Miami Computerized Functional Assessment Scale (CFAS), Preclinical Alzheimer's Cognitive Composite (PACC), Alzheimer's Disease Assessment Scale-Cognitive Scale (ADAS-Cog), and Functional Assessment Questionnaire (FAQ)
Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
60 Years to 85 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
4
States / cities
Los Angeles, California • Miami, Florida • Manhasset, New York + 1 more
Conditions
Frontotemporal Dementia, Behavioral Variant Frontotemporal Dementia
Interventions
Assessments
Other
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 80 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • Boca Raton, Florida + 8 more
Completed Phase 2 Interventional Accepts healthy volunteers

CRT-Guanfacine for SPD

NCT02524899
Conditions
Schizotypal Personality Disorder, SPD
Interventions
Cognitive Remediation Therapy, Guanfacine, Placebo
Behavioral · Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
NeuroQuant, Automated Neuropsychological Assessment Matrices, EDSS, Physical Examination
Other
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 55 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Fear of Spiders, Acute Stress Reaction
Interventions
Propranolol, Hydrocortisone, Placebo (oral), Placebo (IM)
Drug
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 40 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Terminated No phase listed Observational Accepts healthy volunteers

Long-term Clinical Correlates of Traumatic Brain Injury

NCT01132898
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
354 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Active, not recruiting Not applicable Interventional

Impact of Intensive Computerized Cognitive Training

NCT06130735
Conditions
Acquired Brain Injury, Mild Cognitive Impairment, Mild Neurocognitive Disorder
Interventions
Cognitive Computerized Training
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Citicoline, Creatine, and Omega-3 Effects in Middle Age Women

NCT01502813
Conditions
Cognitive Benefits
Interventions
Citicoline, Omega-3 Fatty Acids and Creatine
Drug
Lead sponsor
Deborah Yurgelun-Todd
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
AIDS Dementia Complex, HIV Infections
Interventions
Zidovudine
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
12 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1990
U.S. locations
12
States / cities
Los Angeles, California • New Orleans, Louisiana • Baltimore, Maryland + 6 more
Terminated Not applicable Interventional Results available

Effect of Raised CBF During CEA on Cognition in DM Patients

NCT00597545
Conditions
Carotid Artery Disease, Carotid Artery Stenosis, Diabetes, Cognitive Dysfunction
Interventions
Carotid endarterectomy, Shunt
Procedure · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Mild Traumatic Brain Injury, Post-Concussive Symptoms
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 45 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Completed No phase listed Observational Accepts healthy volunteers

Neuroimaging Studies of Depression in Parkinson's Disease

NCT00518258
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Lee Blonder
Other
Eligibility
40 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Carotid Artery Disease, Carotid Artery Stenosis, Stroke, Transient Ischemic Attack
Interventions
Angioplasty, Stent, Neurological and neuropsychological evaluations, Angiography
Procedure · Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational Results available

PatiEnt Neuropsychological outcomeS After laseR Ablation

NCT05075850
Conditions
Cognitive Change
Interventions
Neuroblate System
Device
Lead sponsor
Monteris Medical
Industry
Eligibility
16 Years and older
Enrollment
81 participants
Timeline
2021 – 2023
U.S. locations
7
States / cities
Little Rock, Arkansas • Orlando, Florida • Kansas City, Kansas + 3 more
Conditions
Multiple Sclerosis
Interventions
Not listed
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
4
States / cities
Teaneck, New Jersey • West Orange, New Jersey • Buffalo, New York + 1 more
Conditions
Traumatic Brain Injury
Interventions
Intravenous sedation using propofol, Intravenous sedation with midazolam
Drug
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Lansing, Michigan
Conditions
Marijuana Dependence
Interventions
Standard CBT, CBT+CM/adherence, CM/abstinence, CM/abstinence+CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Active, not recruiting Early Phase 1 Interventional

Modafinil and Cognitive Function in POTS

NCT01988883
Conditions
Postural Tachycardia Syndrome
Interventions
Placebo, Modafinil, Propranolol
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Childhood Malignant Neoplasm
Interventions
Cognitive Assessment, Quality-of-Life Assessment
Procedure · Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
1 Month and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
163
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 119 more
Conditions
Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Metastases, Neoplasm
Interventions
Motexafin Gadolinium
Drug
Lead sponsor
Pharmacyclics LLC.
Industry
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
44
States / cities
Phoenix, Arizona • Fort Smith, Arkansas • Little Rock, Arkansas + 41 more
Conditions
Healthy Volunteers
Interventions
BPT, NP
Other
Lead sponsor
Lumos Labs, Inc.
Industry
Eligibility
70 Years to 89 Years
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
3
States / cities
Garden Grove, California • Oakland, California • Torrance, California
Terminated No phase listed Observational Accepts healthy volunteers

Study to Validate a Computerized Neuropsychological Test Battery

NCT01421446
Conditions
Healthy Elderly
Interventions
Not listed
Lead sponsor
LifeBridge Health
Other
Eligibility
60 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland