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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:01 PM EDT

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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Numbness Clear all
Terminated Not applicable Interventional Results available

Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN

NCT03206216
View directory record Official record
Conditions
Burning Pain, Impaired Balance, Malignant Ovarian Neoplasm, Numbness, Peripheral Neuropathy, Pain, Acute, Tingling
Interventions
Diode Laser fiber type Selective Stimulator (DLss)
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Results available

Can rTMS Enhance Somatosensory Recovery After Stroke?

NCT02811913
View directory record Official record
Conditions
Stroke
Interventions
repetitive transcranial magnetic stimulation (rTMS), peripheral sensory stimulation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 29, 2022 · Synced Oct 21, 2026, 1:01 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

NCT06094257
View directory record Official record
Conditions
Sensation Disorders, Sensation, Phantom, Pain, Postoperative, Pain, Chronic, Numbness, Sensory Disorder, Sensory Defect, Phantom Pain, Phantom Sensation
Interventions
Sensory testing
Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2033
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve Compression

NCT00703209
View directory record Official record
Conditions
Painful Diabetic Neuropathy
Interventions
Nerve Decompression
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With Cancer

NCT01196442
View directory record Official record
Conditions
Cancer-related Problem/Condition, Neurotoxicity, Pain, Peripheral Neuropathy
Interventions
electrical stimulation pain therapy, questionnaire administration
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 23, 2013 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Lidocaine Versus Bupivacaine in Orthognathic Surgery

NCT06450028
View directory record Official record
Conditions
Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
Interventions
10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
15 Years to 35 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 21, 2026, 1:01 PM EDT
Enrolling by invitation Not applicable Interventional

Percussive vs. Gentle Massage for Recovery After Hip Replacement

NCT07790705
View directory record Official record
Conditions
Paresthesia, Total Hip Arthroplasty (THA), Direct Anterior Total Hip Arthroplasty, Lateral Femoral Cutaneous Nerve Injury
Interventions
Percussive Massage Therapy (Toloco or Hyperice Hypervolt GO 2), Gentle Manual Massage
Device · Other
Lead sponsor
Zachary M Ricciardelli
Network
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cumming, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional

Feasibility Study for Electroacupuncture for Chemotherapy- Induced Peripheral Neuropathy (CIPN)

NCT04092764
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Electroacupuncture, NeuroMetrix, Rydel-Seiffer tuning fork
Device
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Oct 21, 2026, 1:01 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Peer Support for Patients With Diabetic Foot Ulcers

NCT06004219
View directory record Official record
Conditions
Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot, Diabetes Complications, Peripheral Neuropathy
Interventions
Peer counseling group
Behavioral
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
3
States / cities
Downey, California • Los Angeles, California • Pomona, California
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 21, 2026, 1:01 PM EDT
Not listed Phase 2 Interventional

A Clinical Outcomes Study to Measure Reduction in Pain and Numbness During Administration of an Amino Acid Formulation in Subjects Diagnosed With Peripheral Neuropathy

NCT01537705
View directory record Official record
Conditions
Diabetic Neuropathy, Chemotherapy Induced Neuropathy, HIV Neuropathy, Trauma Induced Neuropathy
Interventions
Neuron012703 (Medical Food)
Drug
Lead sponsor
Targeted Medical Pharma
Industry
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2012 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Phase 2 Interventional

Study of NV-101 for Safety and Efficacy in Pediatric Dental Patients Undergoing Procedures

NCT00309322
View directory record Official record
Conditions
Anesthesia, Dental
Interventions
Phentolamine Mesylate (NV-101)
Drug
Lead sponsor
Novalar Pharmaceuticals, Inc.
Industry
Eligibility
4 Years to 11 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 17, 2006 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The THINK Study Incidence of Neurotrophic Keratopathy)

NCT06482164
View directory record Official record
Conditions
Dry Eye
Interventions
Dry Eye Disease
Diagnostic Test
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Laguna Beach, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multimodal Haptic Feedback for Plantar Sensory Substitution

NCT06232512
View directory record Official record
Conditions
Hypoesthesia
Interventions
Haptic Device
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 21, 2026, 1:01 PM EDT
Completed No phase listed Observational

Percutaneous Versus Open Plate Fixation of Diaphyseal Clavicle Fractures

NCT01405703
View directory record Official record
Conditions
Clavicle Fracture
Interventions
xrays
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 9, 2015 · Synced Oct 21, 2026, 1:01 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C

NCT04012996
View directory record Official record
Conditions
Symptomatic Cervical Disc Disease
Interventions
prodisc C SK and/or Vivo, Mobi-C Cervical Disc
Device
Lead sponsor
Centinel Spine
Industry
Eligibility
18 Years to 69 Years
Enrollment
390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
30
States / cities
Flagstaff, Arizona • Beverly Hills, California • Los Angeles, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 21, 2026, 1:01 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

The PAIN (Pelvic Area Injection for Numbness) Study

NCT05972681
View directory record Official record
Conditions
Vaginal Laceration During Delivery
Interventions
Bupivacaine, Epinephrine, Sham normal saline arm
Drug · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 21, 2026, 1:01 PM EDT
Terminated Phase 3 Interventional Results available

A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia

NCT01364259
View directory record Official record
Conditions
Trigeminal Neuralgia
Interventions
Amifostine, CyberKnife stereotactic radiosurgery
Drug · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 21, 2026, 1:01 PM EDT
Completed No phase listed Observational

Diffusion Tensor Imaging Magnetic Resonance Imaging (DTI MRI) as a Correlate to Pain Relief and Facial Numbness in Patients Following Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia

NCT01364272
View directory record Official record
Conditions
Trigeminal Neuralgia
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-surgical Intervention for Carpal Tunnel Syndrome

NCT03360344
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Susceptibility to
Interventions
Kinesio 12 inch Tape, Kinesio 4 inch Tape, Cock up Splint and Lumbrical exercises
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 99 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Early Phase 1 Interventional

Fingolimod in Treating Patients With Chemotherapy-Induced Neuropathy

NCT03943498
View directory record Official record
Conditions
Chemotherapy-Induced Peripheral Neuropathy, Numbness, Pain, Tingling
Interventions
Fingolimod, Fingolimod Hydrochloride, Questionnaire Administration
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Rochester, Minnesota • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2023 · Synced Oct 21, 2026, 1:01 PM EDT
Active, not recruiting Not applicable Interventional

Positioning for Hip Arthroscopic Surgery to Reduce Postoperative Numbness

NCT05038709
View directory record Official record
Conditions
Hip Osteoarthritis, Hip Injuries, Hip Sprain, Hip Strain
Interventions
The Pink Pad Hip Kit
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 88 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 21, 2026, 1:01 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Avazzia HVPC Bio-Electrical Stimulation Technology (BEST™) Microcurrent CTS RCT

NCT04271319
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
BEST™ HVPC microcurrent electrical stimulation PRO-SPORT Ultra® Device, Sham PRO-SPORT Ultra® Device
Device
Lead sponsor
Avazzia, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Symptom Management Program for Hemodialysis Patients

NCT01620580
View directory record Official record
Conditions
Haemodialysis-induced Symptom
Interventions
Self-management, Dietary Information
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2012 · Synced Oct 21, 2026, 1:01 PM EDT
Completed Phase 3 Interventional

Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures

NCT00309335
View directory record Official record
Conditions
Anesthesia, Dental
Interventions
Phentolamine Mesylate (NV-101)
Drug
Lead sponsor
Novalar Pharmaceuticals, Inc.
Industry
Eligibility
12 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 17, 2006 · Synced Oct 21, 2026, 1:01 PM EDT