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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obsessive Compulsive Disorder (OCD) Clear all
Completed Not applicable Interventional

Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders

NCT01243606
View directory record Official record
Conditions
Anxiety Disorders, Mood Disorders
Interventions
Single Diagnosis Treatment Protocol, Unified Protocol (UP)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2017 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children

NCT03584945
View directory record Official record
Conditions
Obsessive-compulsive Disorders and Symptoms in Children
Interventions
Cognitive Behavioral Therapy, Community Referral as appropriate
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 14 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Ann Arbor, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Comparison of Treatment for Hoarding Disorder

NCT02040805
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Group Cognitive Behavioral Therapy, Peer Facilitated Support Group
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 4 Interventional

Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections

NCT00001658
View directory record Official record
Conditions
Autoimmune Disease, Mental Disorder, Obsessive Compulsive Disorder, Streptococcal Infection, Tic Disorder
Interventions
Amoxicillin
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 4 Interventional

Escitalopram for the Treatment of Obsessive Compulsive Disorder (OCD)

NCT00116532
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Escitalopram
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2007 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Not applicable Interventional

ERP Plus Improv Group Therapy for OCD (IMPROVE Study)

NCT06265233
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Group Improv sessions, Group Exposure and Response Prevention (ERP) Therapy
Other · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 1 Interventional

Self-control and Body-focused Repetitive Behaviors

NCT04455152
View directory record Official record
Conditions
Trichotillomania (Hair-Pulling Disorder), Skin-Picking
Interventions
self-control
Behavioral
Lead sponsor
American University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 17, 2026, 4:09 AM EDT
Withdrawn Phase 2 Interventional

Trial of Low-Dose Xenon For The Treatment Of Obsessive-Compulsive Disorder

NCT02098148
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Xenon, Placebo
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2014 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 3 Interventional

Behavior Therapy for Children and Adolescents With Obsessive-Compulsive Disorder (OCD)

NCT00000386
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure and Response Prevention, Family Treatment Program, Relaxation Training, Behavior therapy, Family Counseling
Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
8 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2003
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2008 · Synced Sep 17, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Interpretation Bias as a Mechanism of Treatment Response in OCD

NCT05224414
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive bias modification for interpretation bias, Psychoeducation
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 17, 2026, 4:09 AM EDT
Active, not recruiting Phase 2Phase 3 Interventional

Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors

NCT05796752
View directory record Official record
Conditions
Skin-Picking, Trichotillomania (Hair-Pulling Disorder)
Interventions
Memantine, ComB Behavioral Therapy
Drug · Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 17, 2026, 4:09 AM EDT
Completed No phase listed Observational

Genetics of Obsessive-Compulsive Disorder

NCT00001548
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
1,067 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Neuromodulation for Comorbid Hoarding Disorder and Depression

NCT05985356
View directory record Official record
Conditions
Hoarding Disorder, Hoarding, Depression
Interventions
iTBS
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 17, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

A Precision Medicine Approach to Target Engagement for Emotion Regulation

NCT05651295
View directory record Official record
Conditions
Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder, Obsessive-Compulsive Disorder, Posttraumatic Stress Disorder, Eating Disorders
Interventions
Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions
Behavioral
Lead sponsor
Matthew Southward, PhD
Other
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 1 Interventional

Psilocybin for Treatment of Obsessive Compulsive Disorder

NCT03300947
View directory record Official record
Conditions
Obsessive-compulsive Disorder (OCD)
Interventions
Psilocybin 100 mcg/kg, Psilocybin 300 mcg/kg, Lorazepam 1 mg
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Adjunctive Troriluzole in Obsessive-Compulsive Disorder

NCT04693351
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Troriluzole, Placebo
Drug
Lead sponsor
Biohaven Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
589 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
49
States / cities
Phoenix, Arizona • Culver City, California • La Jolla, California + 45 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Not applicable Interventional

Habit Reversal Training for Children and Adolescents With Trichotillomania

NCT01445444
View directory record Official record
Conditions
Trichotillomania
Interventions
Habit Reversal Training
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Mar 9, 2016 · Synced Sep 17, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Anxiety Skills Study

NCT07774481
View directory record Official record
Conditions
Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders, Social Anxiety Disorder, Panic Disorder (With or Without Agoraphobia), Generalized Anxiety Disorder, Obsessive-Compulsive Disorder, Specific Phobia
Interventions
Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 3 Interventional Results available

Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder

NCT00674219
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Interventions
Memantine
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 64 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Sep 17, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

NCT05467683
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
Interventions
Exposure-Based Therapy
Behavioral
Lead sponsor
Jasper A. Smits
Other
Eligibility
18 Years to 70 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)

NCT02422290
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Ketamine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
14 Years to 22 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Not applicable Interventional

Evaluation of a Brief Surf the Urge Intervention

NCT02771886
View directory record Official record
Conditions
Substance Use, Deliberate Self-harm, Trichotillomania, Aggression, Stealing, Eating Pathology, Gambling
Interventions
Surf the Urge
Behavioral
Lead sponsor
Kimberly N Schubert
Other
Eligibility
14 Years to 24 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Youth Mayo Clinic Anxiety Coach Pilot Study

NCT02205177
View directory record Official record
Conditions
Anxiety
Interventions
Mayo Clinic Anxiety Coach
Device
Lead sponsor
Stephen Whiteside
Other
Eligibility
7 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 4, 2019 · Synced Sep 17, 2026, 4:09 AM EDT
Completed Phase 3 Interventional

Study to Determine the Efficacy and Safety of Adjunctive Topiramate in the Treatment of Obsessive-Compulsive Disorder

NCT00187928
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Topiramate
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 4, 2011 · Synced Sep 17, 2026, 4:09 AM EDT