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ClinicalTrials.gov public records Last synced Oct 24, 2026, 11:04 AM EDT

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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Sleep Apnea of Child Clear all
Completed No phase listed Observational Accepts healthy volunteers

Behavioral Effects of Obstructive Sleep Apnea in Children

NCT00060723
View directory record Official record
Conditions
Sleep-disordered Breathing, Sleep Apnea, Obstructive, ADHD
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
5 Years to 12 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional

Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea

NCT00310323
View directory record Official record
Conditions
Sleep Apnea
Interventions
Dextromethorphan, Caffeine
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
4 Years to 16 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
2
States / cities
Louisville, Kentucky • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 19, 2009 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional Results available

Childhood Adenotonsillectomy Study for Children With OSAS

NCT00560859
View directory record Official record
Conditions
Obstructive Sleep Apnea, Snoring
Interventions
Adenotonsillectomy (AT) - removal of adenoids and tonsils, Watchful Waiting
Procedure · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
5 Years to 9 Years
Enrollment
453 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
6
States / cities
Boston, Massachusetts • St Louis, Missouri • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced Oct 24, 2026, 11:04 AM EDT
Recruiting Phase 2 Interventional

Down Syndrome Obstructive Sleep Apnea

NCT06043440
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Oxygen
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Los Angeles, California • Ann Arbor, Michigan • Cincinnati, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mask Study: One-handed vs. Two Handed Technique in Children

NCT03215121
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Year to 8 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 23, 2020 · Synced Oct 24, 2026, 11:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study

NCT01349205
View directory record Official record
Conditions
Obstructive Sleep Apnea, Enlargement of Tonsil or Adenoid
Interventions
Caffeine and sodium Benzoate 10 mg/kg IV, Caffeine and Sodium Benzoate 20 mg/kg IV, 0.9 NS Saline
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
2 Years to 12 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 24, 2026, 11:04 AM EDT
Completed No phase listed Observational Results available

Effect of Opioids on Ventilation in Children With Obstructive Sleep Apnea

NCT03938259
View directory record Official record
Conditions
Respiratory Depression, Obstructive Sleep Apnea
Interventions
Fentanyl
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
2 Years to 8 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2024 · Synced Oct 24, 2026, 11:04 AM EDT
Not listed No phase listed Observational

Use of Analgesics and Pain Scores After Pediatric Adenotonsillectomy

NCT04349397
View directory record Official record
Conditions
Pain, Postoperative, Obstructive Sleep Apnea of Child
Interventions
Medication Tracking Form
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
3 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 24, 2026, 11:04 AM EDT
Completed No phase listed Observational

Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents

NCT00222963
View directory record Official record
Conditions
Obesity, Obstructive Sleep Apnea Syndrome
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
8 Years to 18 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2009 · Synced Oct 24, 2026, 11:04 AM EDT
Completed No phase listed Observational

Surgical Treatment of Children With OSA and Small Tonsils or Down Syndrome

NCT05154214
View directory record Official record
Conditions
Obstructive Sleep Apnea of Child
Interventions
Adenotonsillectomy, Drug-induced sleep endoscopy directed surgery
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
2 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Phase 4 Interventional Results available

Effect of Ketorolac on Post Adenotonsillectomy Pain

NCT03467750
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Ketorolac, Standard of Care
Drug
Lead sponsor
Emory University
Other
Eligibility
2 Years to 18 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

WatchPAT Device Validation Study Compared to Polysomnography

NCT03188718
View directory record Official record
Conditions
Sleep Apnea Syndromes, Sleep Disorder, Sleep
Interventions
WatchPAT Intervention
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
4 Years to 12 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cytokine Persistence as a Marker of Inflammation in the at Risk, Low Socioeconomic Status Pediatric Population

NCT03134300
View directory record Official record
Conditions
Obstructive Sleep Apnea of Child
Interventions
Cytokine from blood
Diagnostic Test
Lead sponsor
Baylor College of Medicine
Other
Eligibility
5 Years to 10 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Oct 24, 2026, 11:04 AM EDT
Recruiting Not applicable Interventional

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

NCT06258837
View directory record Official record
Conditions
Otolaryngological Disease, Obstructive Sleep Apnea
Interventions
DISE-Directed Surgery, Adenotonsillectomy
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
2 Years to 17 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Ann Arbor, Michigan • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional Results available

Comparing Auto-adjustable Positive Airway Pressure to Continuous Positive Airway Pressure in Children With Sleep Apnea

NCT01846988
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
crossover treatment (REMstar Auto A-Flex)
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 20 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Phase 4 Interventional Results available

Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea

NCT01344759
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Dexmedetomidine, Propofol
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Months to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 24, 2026, 11:04 AM EDT
Withdrawn Phase 2 Interventional

Controlled Trial on Effect of Montelukast Treatment in Children With Obstructive Sleep Apnea Syndrome

NCT00599534
View directory record Official record
Conditions
Sleep Apnea
Interventions
Montelukast, Placebo
Drug
Lead sponsor
University of Louisville
Other
Eligibility
2 Years to 9 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Oct 24, 2026, 11:04 AM EDT
Withdrawn Not applicable Interventional

Airway Ultrasound Prediction and Correlation

NCT03313947
View directory record Official record
Conditions
Obstructive Sleep Apnea, Difficult Airway
Interventions
Ultrasound, Questionnaire
Procedure · Other
Lead sponsor
Vidya Raman
Other
Eligibility
3 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 24, 2026, 11:04 AM EDT
Terminated Not applicable Interventional Results available

The Role of Obstructive Sleep Apnea in Children With Fatty Liver Disease

NCT02134522
View directory record Official record
Conditions
Non Alcoholic Fatty Liver Disease
Interventions
Continuous positive airway pressure (CPAP).
Device
Lead sponsor
Yale University
Other
Eligibility
9 Years to 21 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 8, 2018 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Phase 2 Interventional Results available

The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).

NCT00273754
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Tonsillectomy, Adenoidectomy, Postoperative Complications
Interventions
Caffeine, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
30 Months to 18 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 16, 2016 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Adherence and Therapeutic Effectiveness of Bi-Flex Versus CPAP in Children With OSA

NCT00458406
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Bi-Flex, CPAP
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 16 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Adenotonsillectomy on Quality of Life in Children With Mild Obstructive Sleep Apnea

NCT01539278
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Adenotonsillectomy, Observation alone / no intervention
Procedure · Other
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
3 Years to 16 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2015 · Synced Oct 24, 2026, 11:04 AM EDT
Recruiting Not applicable Interventional

Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy

NCT05575401
View directory record Official record
Conditions
Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children, Sleep Apnea, Obstructive, Tonsillitis, Tonsillar Hypertrophy, Tonsil Stone, Tonsil Disease
Interventions
Lateral pharyngoplasty, Tonsillectomy
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
3 Years to 17 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
4
States / cities
Murrieta, California • Riverside, California • San Bernardino, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 24, 2026, 11:04 AM EDT
Completed Not applicable Interventional

HSAT for OSA Management in Children

NCT05516524
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes, Sleep Disturbance
Interventions
Home sleep apnea test, PSG
Diagnostic Test
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 12 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 24, 2026, 11:04 AM EDT