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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Onychomycosis Clear all
Terminated Phase 3 Interventional

Safety & Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails

NCT01208168
View directory record Official record
Conditions
Onychomycosis
Interventions
NAB001, Vehicle alone
Drug
Lead sponsor
Promius Pharma, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
22
States / cities
Phoenix, Arkansas • Encino, California • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 1 Interventional

A Study of the Systemic Absorption of MOB015B

NCT03244280
View directory record Official record
Conditions
Onychomycosis
Interventions
MOB015B
Drug
Lead sponsor
Moberg Pharma AB
Industry
Eligibility
12 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Jul 21, 2026, 7:29 PM EDT
Not listed Not applicable Interventional

Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis

NCT06074315
View directory record Official record
Conditions
Distal Lateral Subungual Onychomycosis, Onychomycosis
Interventions
Nail Genesis DLSO Product, Nail Genesis DLSO Product (vehicle only)
Device
Lead sponsor
Nail Genesis LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
10
States / cities
Fayetteville, Arkansas • Montclair, California • Sacramento, California + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 2 Interventional

Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME II)

NCT00679601
View directory record Official record
Conditions
Onychomycosis
Interventions
AN2690
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Bryan, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Not applicable Interventional

Pilot Study to Evaluate Plasma Treatment of Onychomycosis

NCT01819051
View directory record Official record
Conditions
Onychomycosis
Interventions
MOE Antimicrobial Plasma Treatment System
Device
Lead sponsor
Moe Medical Devices
Industry
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Jul 21, 2026, 7:29 PM EDT
Not listed Phase 3 Interventional

TDT 067 Onychomycosis Study

NCT01145807
View directory record Official record
Conditions
Onychomycosis
Interventions
TDT067, Placebo, Transfersome
Drug
Lead sponsor
Celtic Pharma Development Services
Industry
Eligibility
18 Years to 75 Years
Enrollment
738 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Albequerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 31, 2012 · Synced Jul 21, 2026, 7:29 PM EDT
Not listed Phase 1 Interventional

Safety and Tolerability Study of SKX-16 in Subjects With Moderate to Severe Distal Subungual Onychomycosis

NCT05110638
View directory record Official record
Conditions
Onychomycosis of Toenail
Interventions
SKX-16 (Luliconazole 10% Solution)
Drug
Lead sponsor
SATO Pharmaceutical Co., Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Jun 13, 2022 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenail

NCT00453271
View directory record Official record
Conditions
Onychomycosis
Interventions
NB-002, Vehicle control
Drug
Lead sponsor
NanoBio Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
13
States / cities
Miami, Florida • Boise, Idaho • Evansville, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated May 22, 2013 · Synced Jul 21, 2026, 7:29 PM EDT
Not listed Phase 2Phase 3 Interventional

Treating Onychomychosis

NCT00776464
View directory record Official record
Conditions
Onychomycosis
Interventions
Noveon laser
Device
Lead sponsor
Nomir Medical Technologies
Industry
Eligibility
18 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2008 · Synced Jul 21, 2026, 7:29 PM EDT
Completed No phase listed Observational

An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection

NCT05202366
View directory record Official record
Conditions
Fungal Infection, Onychomycosis, Tinea Unguium
Interventions
CGB-400 Topical Gel
Drug
Lead sponsor
CAGE Bio Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioequivalency Study of Terbinafine Tablets Under Fed Conditions

NCT00602251
View directory record Official record
Conditions
Onychomycosis
Interventions
Terbinafine
Drug
Lead sponsor
Roxane Laboratories
Industry
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Jul 21, 2026, 7:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Spread of Dermatophytes Among Families

NCT00233493
View directory record Official record
Conditions
Onychomycosis, Tinea Pedis
Interventions
Not listed
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
14 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail

NCT01302119
View directory record Official record
Conditions
Onychomycosis of Toenails
Interventions
AN2690 Topical Solution, 5%, Solution Vehicle
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
604 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
26
States / cities
Phoenix, Arizona • Novato, California • Oceanside, California + 22 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Efinaconazole 10% Solution in the Treatment of Onychomycosis in Diabetic Patients

NCT03168841
View directory record Official record
Conditions
Onychomycosis
Interventions
Efinaconazole Topical
Drug
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study of the Effects of Increasing Doses of a Drug for the Treatment of Nail Fungus

NCT01014962
View directory record Official record
Conditions
Onychomycosis
Interventions
Albaconozole, Placebo
Drug
Lead sponsor
Stiefel, a GSK Company
Industry
Eligibility
18 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Compare the Blood Levels of Albaconazole in Healthy Subjects Who Have Received a Single Dose of 400 mg Albaconazole as a Tablet Versus Albaconazole as a Capsule

NCT01039883
View directory record Official record
Conditions
Onychomycosis
Interventions
Albaconazole tablet 400mg, Albaconazole 100mg capsules, then albaconazole 400mg tablet
Drug
Lead sponsor
Stiefel, a GSK Company
Industry
Eligibility
18 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 2 Interventional

Deposition of Terbinafine After Iontophoretic Application of ETS Terbinafine Gel in Subjects With Distal Subungual Onychomycosis in the Great Toenail

NCT01484145
View directory record Official record
Conditions
Onychomycosis
Interventions
Terbinafine HCl
Drug
Lead sponsor
Nitric BioTherapeutics, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2012 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 3 Interventional Results available

Efficacy Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenail

NCT00443820
View directory record Official record
Conditions
Onychomycosis
Interventions
terbinafine, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
12 Years to 75 Years
Enrollment
526 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
20
States / cities
Novato, California • Northglenn, Colorado • Melbourne, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2011 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Not applicable Interventional

Blue Light Photodynamic Therapy Treatment for Distal and Lateral Subungual Toenail Onychomycosis

NCT03022903
View directory record Official record
Conditions
Toenail Onychomycosis, Distal and Lateral Subungual Toenail Onychomycosis
Interventions
Aminolevulinic Acid (ALA)
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 70 Years · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Jul 21, 2026, 7:29 PM EDT
Not listed Not applicable Interventional

Evaluating the Safety, Tolerability and Preliminary Efficacy of Plasma in Improving the Appearance of Onychomycosis

NCT02724384
View directory record Official record
Conditions
Onychomycosis
Interventions
MOE Plasma Delivery System A, MOE Plasma Delivery System B
Device
Lead sponsor
Moe Medical Devices
Industry
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Quincy, Massachusetts • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Jul 21, 2026, 7:29 PM EDT
Not listed Phase 2 Interventional

Using Light Therapy to Treat Toe Nail Fungus

NCT00771732
View directory record Official record
Conditions
Onychomycosis
Interventions
light therapy
Device
Lead sponsor
Nomir Medical Technologies
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Southborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 12, 2008 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 4 Interventional

Topical Penlac Nail Lacquer for Onychomycosis in Children

NCT01419847
View directory record Official record
Conditions
Onychomycosis
Interventions
Ciclopirox, Placebo
Drug
Lead sponsor
Rady Children's Hospital, San Diego
Other
Eligibility
2 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2011 · Synced Jul 21, 2026, 7:29 PM EDT
Completed Phase 2 Interventional

Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME I)

NCT00680160
View directory record Official record
Conditions
Onychomycosis
Interventions
AN2690
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Bryan, Texas
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Jul 21, 2026, 7:29 PM EDT
Not listed Phase 2 Interventional

To Evaluate Hallux Terbinafine Subungual Gel (HSG) in the Treatment of Onychomycosis

NCT05135910
View directory record Official record
Conditions
Onychomycosis of Toenail
Interventions
Hallux Terbinafine Subungual Gel
Drug
Lead sponsor
Hallux, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Mesa, Arizona • Parker, Colorado • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Jul 21, 2026, 7:29 PM EDT