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Conditions: Postoperative Pain
Interventions: Plain bupivacaine, Liposomal bupivacaine; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Aortic Aneurysm
Interventions: Endovascular Repair, Standard Open Repair; Procedure
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years and older
Enrollment: 881 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2012
U.S. locations: 42
States / cities: Birmingham, Alabama • Tucson, Arizona • No. Little Rock, Arkansas + 39 more

Conditions: Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Neoplasms, Endometrial Cancer
Interventions: Relacorilant 150 mg once daily (QD), Nab-paclitaxel 80 mg/m^2, Bevacizumab 10 mg/kg; Drug
Lead sponsor: Corcept Therapeutics; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 16
States / cities: Birmingham, Alabama • Palo Alto, California • San Francisco, California + 13 more

Conditions: Hernia, Incisional Hernia, Hernia, Inguinal, Indirect, Hernia, Inguinal, Direct, Inguinal Hernia
Interventions: Hernia repair; Procedure
Lead sponsor: Intuitive Surgical; Industry
Eligibility: 18 Years and older
Enrollment: 944 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 17
States / cities: Beverly Hills, California • Nashville, California • Oakland, California + 14 more

Conditions: Post-Operative Pain
Interventions: Sufentanil NanoTab PCA System/15 mcg, morphine IV PCA; Drug
Lead sponsor: Talphera, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 357 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 16
States / cities: Florence, Alabama • Montgomery, Alabama • Sheffield, Alabama + 13 more

Conditions: Urinary Tract Infections, Pyelonephritis Acute, Intraabdominal Infections
Interventions: Sulopenem; Drug
Lead sponsor: Iterum Therapeutics, International Limited; Industry
Eligibility: 12 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Hernia, Hernia, Ventral, Hernia, Abdominal, Hernia Abdominal Wall
Interventions: Transorb™ Self-Gripping Resorbable Mesh; Device
Lead sponsor: Medtronic - MITG; Industry
Eligibility: 18 Years and older
Enrollment: 163 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 6
States / cities: Evanston, Illinois • Lexington, Kentucky • Wilmington, North Carolina + 3 more

Conditions: Trauma to the Abdomen
Interventions: Not listed
Lead sponsor: Denver Health and Hospital Authority; Other
Eligibility: 18 Years to 98 Years
Enrollment: 515 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2022
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Ulcerative Colitis, Familial Polyposis
Interventions: SprayShield Adhesion Barrier System, Good Surgical Technique Alone; Device · Procedure
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Bedford, Massachusetts

Conditions: Central Abdominal Bulging
Interventions: LIPO-202; Drug
Lead sponsor: Neothetics, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2015
U.S. locations: 8
States / cities: Englewood, Colorado • Coral Gables, Florida • Snellville, Georgia + 5 more

Conditions: Gastric Foreign Body, Nos, Disorder of Abdomen (Disorder), Foreign Body in Esophagus, Prostatic Diseases, Disease of Small Intestine
Interventions: Natural Orifice Transluminal Endoscopic Surgery (NOTES), Natural Orifice Translumenal Endoscopic Surgery (NOTES); Procedure
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Ventral Hernia
Interventions: Repair of ventral hernia using biologic mesh, Repair of ventral hernia using suture repair or synthetic mesh; Procedure
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Ventral Hernia, Abdominal Hernia
Interventions: BOTOX Dose A, Placebo for BOTOX, BOTOX Dose B, BOTOX Dose C; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Mineola, New York • Charlotte, North Carolina

Conditions: Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
Interventions: Bupivicaine, Fentanyl, Thoracic epidural analgesia, Hydromorphone, Acetaminophen, Ketorolac, magnesium sulfate, Tramadol, Gabapentin, Cyclobenzaprine, transversus abdominis plane block; Drug · Device · Procedure
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Compartment Syndromes
Interventions: Percutaneous catheter drainage; Procedure
Lead sponsor: Orlando Regional Medical Center; Other
Eligibility: 15 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Necrotizing Pancreatitis
Interventions: Using ABTHERA Advance without a Wittmann Patch; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 22 Years and older
Enrollment: 3 participants
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Neoplasms
Interventions: EPO906 (Patupilone), doxorubicin; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 829 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 104
States / cities: Anchorage, Alaska • Flagstaff, Arizona • Scottsdale, Arizona + 82 more

Conditions: Postoperative Pain
Interventions: Continuous Erector Spinae Plane Nerve Block, Continuous Quadratus Lumborum Nerve Block, Single Erector Spinae Plane Nerve Block, Single Quadratus Lumborum Nerve Block, Lidocaine IV, Ropivacaine 0.5% Injectable Solution, Dexamethasone, Dexmedetomidine, Lidocaine; Procedure · Drug
Lead sponsor: Jeremy Kearns; Other
Eligibility: 18 Years to 90 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Complicated Intra-abdominal Infection, Hosptial Acquired Pneumonia, Ventilator Associated Pneumonia
Interventions: ATM-AVI, MTZ, MER, COL; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years and older
Enrollment: 422 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 5
States / cities: Tucson, Arizona • Torrance, California • Springfield, Illinois

Conditions: Ovarian Neoplasms, Peritoneal Neoplasms, Fallopian Tube Neoplasms
Interventions: epothilone b; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2001
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Abdominal Aortic Aneurysm
Interventions: Evolocumab, Placebo; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Moderated-high Risk of Postoperative Pulmonary Complication, Abdominal Surgery Expected More Than Two Hours
Interventions: Alveolar recruitment maneuver, Calculation of optimal PEEP, Postoperative CPAP; Procedure
Lead sponsor: Fundación para la Investigación del Hospital Clínico de Valencia; Other
Eligibility: 18 Years and older
Enrollment: 920 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Gastrointestinal Disorders (FGIDs), Gastrointestinal and Digestive Disorder, Abdominal Pain/ Discomfort, Pain, Functional Dyspepsia
Interventions: Guided Imagery Therapy; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 12 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Austin, Texas • Houston, Texas

Conditions: Inguinal Hernias
Interventions: Standard open tension-free inguinal hernia repair with mesh; Procedure
Lead sponsor: Creighton University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 720 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2004
U.S. locations: 1
States / cities: Omaha, Nebraska

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TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management

Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

A Prospective Study to Compare the Clinical Outcomes, Pain and Patient Quality of Life for Hernia Patients

A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain

Safety, Tolerability, and Pharmacokinetics of Sulopenem in Adolescents

Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia

Enteral Feeding in the Post-Injury Open Abdomen

An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surgery

An Open-Label Study to Evaluate Retreatment With LIPO-202

Transluminal Flexible Endoscopic Procedure in Foregut and Urologic Surgery

Phasix Mesh Use in Complex Open Ventral Hernias Study

A Study to Evaluate Adverse Events and Effectiveness of OnabotulinumtoxinA in Participants Undergoing Open Abdominal Ventral Hernia Repair for the Achievement of Primary Fascial Closure Without the Use of Component Separation Technique

Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release

Percutaneous Catheter Decompression in the Treatment of Elevated Intra-abdominal Pressure

ABTHERA ADVANCE™ Use Without Wittman Patch

Patupilone Versus Doxorubicin in Patients With Ovarian, Primary Fallopian, or Peritoneal Cancer

Continuous Nerve Block Block vs Combination of Single Block Plus Intravenous Lidocaine for Postoperative Pain.

A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria.

EPO906 Therapy in Patients With Advanced Ovarian, Primary Fallopian, or Primary Peritoneal Cancer

Mechanistic Clinical Trial of PCSK9 Inhibition for AAA

Individualized Perioperative Open Lung Ventilatory Strategy

Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children

Inguinal Hernia Management: Watchful Waiting vs. Tension-Free Open Repair