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ClinicalTrials.gov public records Last synced Sep 17, 2026, 5:16 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Orthopaedic Trauma Clear all
Completed Phase 4 Interventional Results available

Methadone Versus Morphine for Orthopedic Surgery Patients

NCT00892606
View directory record Official record
Conditions
Fracture, Pain, Postoperative
Interventions
Methadone, Morphine
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

Emotional Awareness and Expression Therapy for People With Persistent Pain Following Orthopedic Trauma

NCT05989230
View directory record Official record
Conditions
Orthopaedic Trauma, Chronic Pain, Musculoskeletal Injury
Interventions
Emotional Awareness and Expression Therapy
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery

NCT06429267
View directory record Official record
Conditions
Pediatric, Fracture, Orthopedic Devices Associated With Misadventures, Surgical Instruments, Materials and Devices (Including Sutures), Patient Satisfaction
Interventions
Bioabsorbable Screw, Metal/Titanium Screw
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
Up to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Sep 17, 2026, 5:16 AM EDT
Not yet recruiting Not applicable Interventional

Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test

NCT07158892
View directory record Official record
Conditions
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis, Trigger Digit, Dupuytren Contracture, Rotator Cuff Tendinopathy, De Quervain Disease
Interventions
Diagnostic Advance Care Planning Discussion, Informational Statement Only
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Withdrawn Phase 2 Interventional

Open Label Trial of NanoDOX Hydrogel in Orthopedic Trauma Wounds With and Without Vacuum Assisted Closure Therapy

NCT01518491
View directory record Official record
Conditions
Orthopedic Trauma Wounds
Interventions
NanoDOX Hydrogel, VAC Alone
Drug · Other
Lead sponsor
NanoSHIFT LLC
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
2
States / cities
Bethesda, Maryland • Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Sep 17, 2026, 5:16 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Peripheral Nerve Blocks in Pediatric Orthopedic Patients

NCT02236130
View directory record Official record
Conditions
Pediatric Extremity Fracture, Pediatric Extremity Soft Tissue Injury
Interventions
Regional block, General Anesthesia, Local Anesthetic Ropivacaine, Opioids Morphine, Oral pain medication Acetaminophen with Hydrocodone
Procedure · Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
6 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 12, 2017 · Synced Sep 17, 2026, 5:16 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The TCU Division I Collegiate Athlete Study

NCT07006051
View directory record Official record
Conditions
Orthopaedic Injuries, Concussion (Diagnosis)
Interventions
Exposed group
Other
Lead sponsor
Texas Christian University
Other
Eligibility
17 Years to 30 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Not applicable Interventional Results available

Virtual Phone Visits Compared to In-Person Physical Visits for Post-Operative Follow-Up at a Sports Medicine Clinic

NCT05998148
View directory record Official record
Conditions
Patient Satisfaction, Sports Injury, Surgery, Orthopedic Disorder
Interventions
virtual phone appointment visits
Other
Lead sponsor
Jonathan Wu
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain

NCT00685295
View directory record Official record
Conditions
Pain, Fracture, Sprain
Interventions
Fentanyl, Lansoprazole, Oxycodone
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Not applicable Interventional Results available

Prospective Evaluation of Cognitive Outcomes After Anesthesia on Patients in the Beach Chair Position

NCT02674334
View directory record Official record
Conditions
Injury as a Result of Positioning
Interventions
NIRS, NIRS monitored not treated
Device
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 10, 2017 · Synced Sep 17, 2026, 5:16 AM EDT
Terminated Phase 3 Interventional Results available

Ketamine Patient-Controlled Analgesia for Acute Pain

NCT02062879
View directory record Official record
Conditions
Acute Pain, Multiple Trauma, Fractures
Interventions
Ketamine, Hydromorphone
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 20, 2017 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Not applicable Interventional Results available

Toolkit for Optimal Recovery After Orthopedic Injury

NCT04973696
View directory record Official record
Conditions
Acute Orthopedic Injury
Interventions
Toolkit for Optimal Recovery after Orthopedic Injury, Minimally Enhanced Usual Care (MEUC)
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Multi-Center Protocol for Obtaining and Storing Human Samples for Immediate or Future Microbial, Immune, or Host-Microbe Scientific Study

NCT00764023
View directory record Official record
Conditions
Infections
Interventions
Not listed
Lead sponsor
Southwest Regional Wound Care Center
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Phase 4 Interventional

Identifying and Treating Depression in the Orthopaedic Trauma Population

NCT05976347
View directory record Official record
Conditions
Depression
Interventions
Fluoxetine 20 MG, Duloxetine 30 MG, Observation
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Phase 4 Interventional

Length of Post Operative Dressing After Carpal Tunnel Release

NCT01310218
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
extended postoperative dressing, short postoperative dressing
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 7, 2011 · Synced Sep 17, 2026, 5:16 AM EDT
Withdrawn No phase listed Observational

Use of 5-Aminolevulinic Acid to Assess Bone and Tissue Profusion in Orthopaedic Infection Patients

NCT04976049
View directory record Official record
Conditions
Trauma, Infection, Bone Fracture
Interventions
Imaging using 5-Aminolevulinic Acid (5-ALA) during surgery
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 27, 2022 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Early Phase 1 Interventional Results available

IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery

NCT03855059
View directory record Official record
Conditions
Lower Limb Injury
Interventions
Placebos, Dexamethasone Sodium Phosphate
Drug
Lead sponsor
University of Arizona
Other
Eligibility
5 Years to 25 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional

Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture

NCT06869343
View directory record Official record
Conditions
Orthopedic Disorder, Humerus Fracture, Shoulder Arthroplasty, Reverse Shoulder Replacement
Interventions
Physical Therapy
Other
Lead sponsor
University of Virginia
Other
Eligibility
50 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Enrolling by invitation Not applicable Interventional

Immediate Weightbearing vs Delayed Weightbearing

NCT05595148
View directory record Official record
Conditions
Rehabilitation
Interventions
Immediate WBAT, No Intervention: Delayed WBAT
Procedure · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland • Cheverly, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Not applicable Interventional

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

NCT06366633
View directory record Official record
Conditions
Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
Interventions
Web-TIRELESS
Behavioral
Lead sponsor
Jafar Bakhshaie
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 17, 2026, 5:16 AM EDT
Recruiting Phase 4 Interventional

Single Shot Exparel vs Catheters in Lower Extremity Trauma

NCT07221019
View directory record Official record
Conditions
Fracture Dislocation of Ankle Joint, Fracture Leg, Fracture Femur, Fracture Lower Leg, Fracture
Interventions
Bupivacaine, Exparel + Bupivacaine
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Phase 4 Interventional Results available

Assessing the Efficacy of IV Ibuprofen for Treatment of Pain in Orthopedic Trauma Patients

NCT02152163
View directory record Official record
Conditions
Pain
Interventions
IV Ibuprofen, placebo
Drug
Lead sponsor
Delray Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Delray Beach, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Sep 17, 2026, 5:16 AM EDT
Completed Phase 3 Interventional Results available

PREVENTion of Clot in Orthopaedic Trauma

NCT02984384
View directory record Official record
Conditions
Blood Clot, Trauma
Interventions
Acetylsalicylic acid, Low Molecular Weight Heparin (LMWH)
Drug
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years and older
Enrollment
12,424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
19
States / cities
Tucson, Arizona • Miami, Florida • Indianapolis, Indiana + 16 more
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 17, 2026, 5:16 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Ergonomics in the Cardiac Catheterization Laboratory

NCT06506968
View directory record Official record
Conditions
Ergonomics, Orthopedic Injury, Wellness
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 17, 2026, 5:16 AM EDT