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ClinicalTrials.gov public records Last synced Sep 30, 2026, 6:16 PM EDT

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Showing 25–47 of 47 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Osteoporosis Risk Clear all
Completed No phase listed Observational

Bone Mineral Density and Subsequent Cancer Risk

NCT00340262
View directory record Official record
Conditions
Endometrial Cancer, Breast Cancer
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
55 Years to 80 Years · Female only
Enrollment
15,595 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Phase 2 Interventional

Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy

NCT00165204
View directory record Official record
Conditions
Menopause, Postmenopausal Bone Loss, Breast Cancer
Interventions
Tibolone
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 21, 2007 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Not applicable Interventional Results available

Mitigation of Major Hip Injury Due to Fall With a Smart Belt

NCT05245097
View directory record Official record
Conditions
Hip Injuries, Fractures, Hip, Fall Injury, Fall Risk, Osteoporosis, Osteoporosis Risk
Interventions
Tango Belt, Standard of Care (SOC)
Device · Other
Lead sponsor
ActiveProtective Technologies, Inc
Industry
Eligibility
65 Years and older
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
10
States / cities
Sacramento, California • Bensalem, Pennsylvania • Gwynedd, Pennsylvania + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Assessing Risk for Osteoporosis on Physician and Patient Behaviors

NCT01572766
View directory record Official record
Conditions
Osteoporosis, Osteopenia
Interventions
FRAX Assessment Tool
Other
Lead sponsor
Duquesne University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2012 · Synced Sep 30, 2026, 6:16 PM EDT
Completed No phase listed Observational

Genomic Determinants and Shared Genetic Pathways of Periodontal Disease

NCT03437798
View directory record Official record
Conditions
Periodontal Diseases, Diabetes, Osteoporosis, Cardiovascular Risk Factor
Interventions
Disease status
Other
Lead sponsor
Tufts University
Other
Eligibility
45 Years to 100 Years · Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Sep 30, 2026, 6:16 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use

NCT01875458
View directory record Official record
Conditions
Osteoporosis, With or Without Treatment, Bisphosphonate Treatment, Atypical Femur Fracture, Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Healthy Volunteers
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2023 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise as an Modulator of Immunological Risk Factors for Osteoporosis

NCT02765945
View directory record Official record
Conditions
Osteoporosis
Interventions
Supervised exercise program
Other
Lead sponsor
East Tennessee State University
Other
Eligibility
30 Years to 60 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 1998
U.S. locations
1
States / cities
Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated May 9, 2016 · Synced Sep 30, 2026, 6:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

New Tools for Assessing Fracture Risk

NCT02436356
View directory record Official record
Conditions
Osteoporosis, Fracture Risk Assessment
Interventions
Osteoprobe-Reference Point Indentation (RPI), Dual-energy X-ray absorptiometry (DXA) Scans, MRI
Device · Radiation
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 30, 2026, 6:16 PM EDT
Completed No phase listed Observational

Determining the Risk Factors Such as Smoking, Alcohol, and Caffeine and Their Association With Osteoporosis in Men

NCT00011323
View directory record Official record
Conditions
Osteoporosis
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years and older · Male only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
1
States / cities
Jamaica Plain, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Analysis of Bone Micro-Architecture as a Clinical Biomarker for Image-Based Fracture Risk Estimation.

NCT03463850
View directory record Official record
Conditions
Osteoporosis
Interventions
Dual Energy CT (DECT), DEXA
Radiation
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
60 Years and older · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk

NCT04431960
View directory record Official record
Conditions
Postmenopausal Osteoporosis, Gut Microbiota, Cardiovascular Diseases
Interventions
blackcurrant (BC) extract
Drug
Lead sponsor
University of Connecticut
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD

NCT03534934
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive, Osteoporosis
Interventions
Vital signs, Urine Pregnancy Test, Questionnaires, Blood Test, Duel-energy X-ray absorptiometry scan, Multi-detector computed tomography, Dual-energy X-ray absorptiometry scan
Diagnostic Test · Other
Lead sponsor
Punam K Saha
Other
Eligibility
45 Years to 90 Years
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
Iowa City, Iowa • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 30, 2026, 6:16 PM EDT
Completed No phase listed Observational

Longitudinal Study of Bone Mineral Density in Survivors of Solid Pediatric Cancers

NCT00615485
View directory record Official record
Conditions
Osteoporosis
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
7 Years to 40 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2013 · Synced Sep 30, 2026, 6:16 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females

NCT07365514
View directory record Official record
Conditions
Postmenopausal Osteoporosis, Gut Microbiome, Menopause
Interventions
Blackcurrant (BC) extract, Placebo
Drug
Lead sponsor
University of Connecticut
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 30, 2026, 6:16 PM EDT
Withdrawn No phase listed Observational

Evaluation of the Risk for Radiographic and Clinical Nonunion in Patients With Previous Bisphosphonates Therapy.

NCT01731535
View directory record Official record
Conditions
Non-union or Delayed Healing Fractures
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
60 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 12, 2015 · Synced Sep 30, 2026, 6:16 PM EDT
Terminated Phase 2 Interventional

Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk

NCT03113994
View directory record Official record
Conditions
Spinal Cord Injuries, Osteoporosis, Metabolic Syndrome
Interventions
Rosuvastatin Calcium, Placebo Oral Tablet, Coenzyme Q10, Calcium Carbonate, Vitamin D
Drug · Dietary Supplement
Lead sponsor
Dr. B. Catharine. Craven
Other
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 30, 2026, 6:16 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Does Bone Structure Explain the Increased Fracture Risk in Type II Diabetes Patients? A Pilot Study

NCT00703417
View directory record Official record
Conditions
Osteoporosis
Interventions
magnetic Resonance Imaging, Computed Tomography, High resolution peripheral quantitative computed tomography
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 75 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2011 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Improving Osteoporosis Care in High-Risk Home Health Patients

NCT00679198
View directory record Official record
Conditions
Patient Compliance, Communication, Osteoporosis, Fractures, Bone
Interventions
nurse-patient communication
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Up to 95 Years
Enrollment
667 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteoporosis Choice Decision Aid for Use of Bisphosphonates in Postmenopausal Women

NCT00578981
View directory record Official record
Conditions
Osteoporosis, Bone Loss, Age Related, Postmenopausal Bone Loss, Postmenopausal Osteoporosis
Interventions
Osteoporosis Choice Decision Aid
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years to 90 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 30, 2026, 6:16 PM EDT
Recruiting Phase 2 Interventional

Effect of Acetylcholinesterase Inhibitors on Bone Metabolism

NCT06041789
View directory record Official record
Conditions
Osteoporosis
Interventions
Donepezil, Memantine
Drug
Lead sponsor
Duke University
Other
Eligibility
50 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Weight Loss on Bone in Men

NCT00472745
View directory record Official record
Conditions
Weight Loss, BMD
Interventions
Weight Loss, Weight Maintenance
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
50 Years to 72 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 30, 2026, 6:16 PM EDT
Completed Phase 4 Interventional Results available

A Study of Bonviva (Ibandronate) and Alendronate on Renal Function in Postmenopausal Women With Osteoporosis at High Risk for Renal Disease.

NCT00503113
View directory record Official record
Conditions
Post-Menopausal Osteoporosis
Interventions
ibandronate [Bonviva/Boniva], Alendronate
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
60 Years and older · Female only
Enrollment
801 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
15
States / cities
Birmingham, Alabama • Riverside, California • Lakewood, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2011 · Synced Sep 30, 2026, 6:16 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bone UltraSonic Scanner (BUSS) Clinical Optimization Study

NCT01056432
View directory record Official record
Conditions
Osteoporosis
Interventions
Not listed
Lead sponsor
Artann Laboratories
Industry
Eligibility
21 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Sep 30, 2026, 6:16 PM EDT