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Showing 1–24 of 107 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Oxygen Saturation Clear all
Completed No phase listed Observational Accepts healthy volunteers

Accuracy Performance Verification of the INVOS™ PM7100 System in Adults

NCT06581835
View directory record Official record
Conditions
Oxygen Saturation
Interventions
Observational
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Jul 22, 2026, 5:54 AM EDT
Terminated Not applicable Interventional

Effect of NIRS-assisted Assessment on Chronic Lower Extremity and Other Chronic Non-healing Ulcers

NCT06702852
View directory record Official record
Conditions
Ulcers
Interventions
NIRS imaging in addition to SOC
Device
Lead sponsor
Kent Imaging Inc
Industry
Eligibility
18 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
New Braunfels, Texas • San Antonio, Texas • San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Philps FAST2022 picoSAT Pulse Oximetry Desaturation Study

NCT05683366
View directory record Official record
Conditions
SpO2 (Peripheral Oxygen Saturation) Measurement Validation
Interventions
No Intervention
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 50 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Study of Peripheral Capillary Oxygen Saturation (SpO2): Vital Signs Patch (VSP)

NCT01899911
View directory record Official record
Conditions
Desaturation of Blood
Interventions
Vital Signs Patch (VSP)
Device
Lead sponsor
LifeWatch Services, Inc.
Industry
Eligibility
23 Years to 33 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2015 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

Utility of Continuous Pulse Oximetry for Pediatric Patients With Stable Respiratory Illness

NCT04407806
View directory record Official record
Conditions
Respiratory Disease, Asthma in Children, Pneumonia in Children, Bronchiolitis Acute
Interventions
Continous Pulse oximeter, Intermittent Pulse oximeter
Device
Lead sponsor
Corewell Health East
Other
Eligibility
3 Months to 14 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Jul 22, 2026, 5:54 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Hand Perfusion and Pulse Oximetry Performance

NCT06925646
View directory record Official record
Conditions
Oxygen Saturation
Interventions
Finger hyperperfusion via adenosine, Finger hypoperfusion via by norepinephrine, Baseline hypoxic test
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Tissue Oxygenation Measurement Using Multimodal Devices

NCT05784103
View directory record Official record
Conditions
Oxygen Saturation
Interventions
Clarifi Modulum, Perimed PeriFlux 5000, Apple Watch Oxygen Sensor, Innovo iP 900AP
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Indianapolis, Indiana • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational

Impact of Blood Storage Duration on Physiologic Measures

NCT01274390
View directory record Official record
Conditions
Cardiac Surgery, Erythrocyte Transfusion
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
4
States / cities
Boston, Massachusetts • Minneapolis, Minnesota • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep Apnea

NCT03471871
View directory record Official record
Conditions
Obstructive Sleep Apnea, Healthy Subjects
Interventions
Placebo, Lemborexant 10 mg, Lemborexant 25 mg
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
11
States / cities
Glendale, Arizona • Phoenix, Arizona • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2020 · Synced Jul 22, 2026, 5:54 AM EDT
Active, not recruiting Not applicable Interventional

Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension

NCT04938167
View directory record Official record
Conditions
Persistent Pulmonary Hypertension of the Newborn, Hypoxemic Respiratory Failure
Interventions
95% - 99% SpO2 target
Other
Lead sponsor
University of California, Davis
Other
Eligibility
0 Days to 28 Days
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Time Outside Target Oxygen Saturation Range in Preterm Infants and Long Term Outcomes and Preterm Infants

NCT00845624
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
1 Day to 12 Months
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Accuracy Validation of Belun Oxygen Saturation Pulse Oximeter FDA Submission Study

NCT03439306
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse Oximeter
Device
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 50 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational

Near Infrared Spectroscopy (St02)

NCT01062685
View directory record Official record
Conditions
Septic Shock
Interventions
Near-infrared spectroscopy assessment
Diagnostic Test
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Jul 22, 2026, 5:54 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Controlled Desaturation Study for Perin Health Patch Validation

NCT06680700
View directory record Official record
Conditions
Oxygen Saturation Measurement
Interventions
Perin Health Patch
Device
Lead sponsor
Perin Health Devices
Industry
Eligibility
18 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Woodland Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Normal Readings and Repeatability Across Skin Colors

NCT01326819
View directory record Official record
Conditions
Near Infrared Spectroscopy
Interventions
Not listed
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 12, 2013 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Accuracy Verification of the INVOS PM7100

NCT07166341
View directory record Official record
Conditions
Tissue Oxygenation
Interventions
Observational
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 46 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Recruiting No phase listed Observational

Endoscopic COlorectal Mucosal Evaluation of Oxygen Tension

NCT07467980
View directory record Official record
Conditions
Anastomotic Leak Rectum, Anastomotic Leak Large Intestine
Interventions
A novel endoscopic imaging system that displays real-time oxygen saturation levels
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Terminated Not applicable Interventional

Women In Steady Exercise Research - Window of Opportunity for Exercise and Tumor Biology

NCT05428709
View directory record Official record
Conditions
Breast Cancer
Interventions
Acute Exercise
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Jul 22, 2026, 5:54 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Performance Comparison of Masimo O3 Regional Oximetry Sensors in Neonates

NCT03828487
View directory record Official record
Conditions
Regional Saturation of Oxygen (rSO2)
Interventions
Masimo O3 Neonatal Sensors, 510(k) cleared sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
Up to 28 Days
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2021 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Phase 3 Interventional

Canadian Oxygen Trial (COT)

NCT00637169
View directory record Official record
Conditions
Respiratory Insufficiency of Prematurity
Interventions
Titration of oxygen therapy
Other
Lead sponsor
McMaster University
Other
Eligibility
Up to 24 Hours
Enrollment
1,201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
3
States / cities
Stony Brook, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 21, 2018 · Synced Jul 22, 2026, 5:54 AM EDT
Not listed Not applicable Interventional

PREMOD2 With Near Infrared Spectroscopy Sub-study

NCT03145142
View directory record Official record
Conditions
Hypoxia, Brain, Premature Birth
Interventions
Umbilical cord milking, Delayed Cord Clamping
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2021 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Philips FAST Evaluation

NCT06860230
View directory record Official record
Conditions
Oxygen Saturation Measurement
Interventions
Philips FAST SpO2 with Nellcor Pulse Oximetry Sensors
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation of Next Generation Cerebral and Tissue Oximeter

NCT03128372
View directory record Official record
Conditions
Oxygen Deficiency
Interventions
Desaturation
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 46 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2018 · Synced Jul 22, 2026, 5:54 AM EDT
Completed No phase listed Observational Results available

Oxygen Saturation Monitoring During Surgery

NCT01098851
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Medtronic - MITG
Industry
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Jul 22, 2026, 5:54 AM EDT