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ClinicalTrials.gov public records Last synced Jul 23, 2026, 1:48 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Infant, Premature, Congenital Heart Disease, Patent Ductus Arteriosus, Necrotizing Enterocolitis
Interventions
Near-infrared spectroscopy (NIRS)
Procedure
Lead sponsor
University of Utah
Other
Eligibility
12 Days to 6 Months
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Conditions
Cardiovascular Diseases, Postoperative Complications
Interventions
INVOS cerebral oximeter
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nonin 4 Wavelength Cerebral Oximeter Study

NCT01762722
Conditions
Healthy
Interventions
Reduction of inspired oxygen
Device
Lead sponsor
Duke University
Other
Eligibility
21 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Super-Oxygenated Water on Blood Oxygen Saturation

NCT07016191
Conditions
Adult Subject
Interventions
Ingestion of Water
Other
Lead sponsor
Inhale, Inc
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Westlake Village, California
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of MABOS for Improved Pulse Oximeter Accuracy in Patients of Color

NCT05995613
Conditions
Oxygen Saturation
Interventions
MABOS, Nonin PureSat
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Hypoxemia, Altitude Hypoxia
Interventions
Continuous positive airway pressure, Ambient air
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Denver, Colorado
Completed Not applicable Interventional Results available

Use of NIRS in Preterm Population Born at Altitude

NCT04639583
Conditions
Prematurity; Extreme
Interventions
Near-infrared spectroscopy (NIRS) utilization
Device
Lead sponsor
University of New Mexico
Other
Eligibility
0 Hours to 24 Hours
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Study of Peripheral Capillary Oxygen Saturation (SpO2): Vital Signs Patch (VSP)

NCT01899911
Conditions
Desaturation of Blood
Interventions
Vital Signs Patch (VSP)
Device
Lead sponsor
LifeWatch Services, Inc.
Industry
Eligibility
23 Years to 33 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
San Francisco, California
Conditions
Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
Interventions
Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
Columbus, Ohio
Conditions
Infant, Premature, Neonatal Respiratory Distress, Oxygen Saturation, Bronchopulmonary Dysplasia
Interventions
Automated Control, Manual Control
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Salt Lake City, Utah • Seattle, Washington
Completed Not applicable Interventional Results available

The Videolaryngoscopy in Small Infants

NCT03396432
Conditions
Surgery, Anesthesia, Endotracheal
Interventions
Video Laryngoscopy for ET placement, Direct Laryngoscopy for ET Placement
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 12 Months
Enrollment
566 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
4
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania • Dallas, Texas + 1 more
Withdrawn No phase listed Observational

Presep and Vascath Interaction Study

NCT00739089
Conditions
Hemodynamics, Renal Dialysis, Sepsis, Shock
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Healthy
Interventions
RD Disposable Sensors
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 45 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Irvine, California
Conditions
Other Preterm Infants
Interventions
Mother-Infant Dyad
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
30 Weeks to 35 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Conditions
Anemia of Prematurity, Necrotizing Enterocolitis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 12 Weeks
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Completed Not applicable Interventional Results available

Neonatal Pulse Oximetry Sensor Study

NCT05250102
Conditions
Premature Birth
Interventions
Pulse oximeter sensors
Device
Lead sponsor
Medline Industries
Industry
Eligibility
1 Day to 28 Days
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Los Angeles, California • Greenville, North Carolina
Conditions
Obstructive Sleep Apnea, Healthy Subjects
Interventions
Placebo, Lemborexant 10 mg, Lemborexant 25 mg
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
11
States / cities
Glendale, Arizona • Phoenix, Arizona • San Diego, California + 7 more
Conditions
Oxidative Stress
Interventions
Titration of oxygen during neonatal resuscitation
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Apnea of Prematurity, Desaturation of Blood, Central Apnea, Periodic Breathing, Obstructive Apnea of Newborn
Interventions
Targeting SpO2 at 93-95%, Targeting SpO2 at 90-92%
Other
Lead sponsor
University of Miami
Other
Eligibility
Up to 18 Weeks
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Recruiting No phase listed Observational Accepts healthy volunteers

Controlled Desaturation Study for Perin Health Patch Validation

NCT06680700
Conditions
Oxygen Saturation Measurement
Interventions
Perin Health Patch
Device
Lead sponsor
Perin Health Devices
Industry
Eligibility
18 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Woodland Hills, California
Conditions
COPD
Interventions
Breath Responsive Variable Bolus Oxygen Conserving Device
Device
Lead sponsor
StratiHealth
Industry
Eligibility
65 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
3
States / cities
Oceanside, California • Vista, California • Westminster, California
Completed No phase listed Observational Accepts healthy volunteers

A Pilot Study Using Photo-plethysmographic (PPG) Camera

NCT01166867
Conditions
Infant Development
Interventions
Photo-plethysmography monitoring
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
1 Minute to 12 Months
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Orange, California
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Normal Readings and Repeatability Across Skin Colors

NCT01326819
Conditions
Near Infrared Spectroscopy
Interventions
Not listed
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Recruiting Not applicable Interventional Accepts healthy volunteers

Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

NCT06373289
Conditions
Bronchopulmonary Dysplasia, Pulmonary Hypertension
Interventions
higher oxygen saturation target using Nellcor pulse oximetry sensors, lower oxygen saturation target using Nellcor pulse oximetry sensors
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Month to 5 Months
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Birmingham, Alabama • New Haven, Connecticut