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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Oxytocin Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Intranasal Oxytocin on Appetite and Caloric Intake in Men and Women

NCT01513499
View directory record Official record
Conditions
Eating Behavior
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2019 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Potential Benefits of the Somatic Psychoeducational Intervention

NCT05766852
View directory record Official record
Conditions
Work Related Stress
Interventions
Somatic Psychoeducational Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 21, 2026, 11:35 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Potential Benefits of Sonic Augmentation Technology in Music

NCT07065227
View directory record Official record
Conditions
Biobehavioral State, Sonic Augmentation Technology, Oxytocin, Autonomic Reactivity
Interventions
Augmented Theme, Mozart Theme
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Early Phase 1 Interventional Results available

Oxytocin on HR in Sleep Apnea Patient

NCT02564068
View directory record Official record
Conditions
Sleep Apnea
Interventions
Oxytocin
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 26, 2023 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Phase 2 Interventional Results available

Oxytocin and Social Cognition in Schizophrenia

NCT00884897
View directory record Official record
Conditions
Social Cognition, Social Anxiety, Emotional Intelligence
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Jul 21, 2026, 11:35 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Brain Blood Flow Changes Elicited by Oxytocin in Volunteers With and Without Schizophrenia

NCT01123317
View directory record Official record
Conditions
Schizophrenia
Interventions
Oxytocin
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 18, 2019 · Synced Jul 21, 2026, 11:35 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

NCT05761860
View directory record Official record
Conditions
Pain
Interventions
OxyCODONE 5 mg Oral Tablet, OxyCODONE 2.5 mg Oral Tablet, Placebo oxyCODONE Oral Tablet, Oxytocin Nasal Spray (48 IU), Placebo Oxytocin Nasal Spray
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Induction of Labor With Oxytocin: When Should Oxytocin be Held?

NCT00957593
View directory record Official record
Conditions
Labor Induction, Cesarean Delivery
Interventions
Oxytocin, Oxytocin discontinuation
Drug
Lead sponsor
Lehigh Valley Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Not applicable Interventional

Adjuvant Oxytocin for Preinduction Ripening With a Foley catheter--a Clinical Trial

NCT00468520
View directory record Official record
Conditions
Pregnancy, Induced Labor, Cervical Ripening
Interventions
low dose oxytocin
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2011 · Synced Jul 21, 2026, 11:35 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Oxytocin and Arginine Vasopressin in Pain Relief

NCT01328561
View directory record Official record
Conditions
Placebo Analgesia
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 55 Years
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Phase 1 Interventional

Brain Imaging of Intranasal Oxytocin Treatment in Autism

NCT01945957
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Oxytocin
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
6 Years to 18 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Jul 21, 2026, 11:35 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Deciphering the Role of Oxytocin in Motivation: an fMRI Study. Part II

NCT02652195
View directory record Official record
Conditions
Healthy Controls, Alcohol Use Disorder
Interventions
Placebo, Oxytocin
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 45 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Jul 21, 2026, 11:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Oxytocin Levels in Typically Developing Boys

NCT02006381
View directory record Official record
Conditions
Healthy Boys
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
3 Years to 17 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 21, 2015 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intranasal Oxytocin and Maternal Neglect

NCT02737436
View directory record Official record
Conditions
Maternal Behavior
Interventions
Intranasal Oxytocin, Placebo, Functional MRI scanning
Drug · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
20 Years to 45 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
2
States / cities
Iowa City, Iowa • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Somatic Psychoeducational Intervention

NCT06580119
View directory record Official record
Conditions
Work Related Stress
Interventions
Somatic Psychoeducational Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Not applicable Interventional Results available

Oxytocin Treatment of Schizophrenia

NCT01028677
View directory record Official record
Conditions
Paranoia, Schizophrenia, Schizoaffective Disorder
Interventions
intranasal spray with oxytocin, nasal spray without oxytocin
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Jul 21, 2026, 11:35 PM EDT
Terminated Not applicable Interventional Results available

Open-label Study of the Efficacy of Intranasal Oxytocin in Schizophrenia

NCT02144155
View directory record Official record
Conditions
Schizophrenia
Interventions
Oxytocin: 24IU - 168 IU, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2019 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Understanding Cognition, Oxytocin & Pain in Elders

NCT03878589
View directory record Official record
Conditions
Knee Osteoarthritis, Osteoarthritis
Interventions
Oxytocin (OT), Placebo (P)
Drug
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 100 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Jul 21, 2026, 11:35 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Does Oxytocin Alter Tolerance to or Motivation for Alcohol

NCT05312008
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Intranasal oxytocin, Intranasal placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 60 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Phase 4 Interventional Results available

Comparison of Low-dose and High-dose Oxytocin Regimens for Labor Augmentation

NCT02487797
View directory record Official record
Conditions
Dystocia
Interventions
Oxytocin, Sodium Chloride 0.9%
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,003 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Phase 4 Interventional Results available

Oxytocin Regimen to Prevent Atony and Postpartum Hemorrhage During Vaginal Delivery: 3-arm RCT

NCT00790062
View directory record Official record
Conditions
Uterine Atony, Postpartum Hemorrhage
Interventions
Oxytocin
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Female only
Enrollment
1,798 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 7, 2016 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Phase 2 Interventional Results available

The Effects of Oxytocin in Obese Adults

NCT03043053
View directory record Official record
Conditions
Obesity
Interventions
oxytocin nasal spray, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Postpartum Oxytocin Administration in the Era of Delayed Cord Clamping

NCT04632264
View directory record Official record
Conditions
Postpartum Hemorrhage
Interventions
Initiation of standard postpartum oxytocin immediately following fetal shoulder delivery, Initiation of standard postpartum oxytocin immediately following placenta delivery, Saline Placebo
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 28, 2021 · Synced Jul 21, 2026, 11:35 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Oxytocin for Oxidative Stress and Inflammation

NCT04732247
View directory record Official record
Conditions
Oxidative Stress, Inflammation
Interventions
Oxytocin nasal spray, Placebo nasal spray
Drug
Lead sponsor
Florida Institute for Human and Machine Cognition
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
Phoenix, Arizona • Gainesville, Florida • Pensacola, Florida
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Jul 21, 2026, 11:35 PM EDT