- Conditions
- 1. Postoperative Cognitive Dysfunction
- Interventions
- The intervention will be Mini-Mental Status Examination (MMSE)
- Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- Loma Linda, California
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Showing 1–10
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- Conditions
- Post-Operative Confusion, Neuroinflammatory Response, Alzheimer Disease
- Interventions
- Montreal Cognitive Assessment, Stroop Test, 4AT Delirium, Grooved Pegboard, NACC Cognitive Battery, ERP Testing, Blood Plasma and Serum sampling, Cerebral Spinal Fluid Sample
- Behavioral · Diagnostic Test
- Lead sponsor
- University of Tennessee Graduate School of Medicine
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Knoxville, Tennessee
- Conditions
- Postoperative Delirium, PD, Postoperative Cognitive Dysfunction, POCD
- Interventions
- Precedex (Dexmedetomidine), Placebo
- Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 68 Years and older
- Enrollment
- 404 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2014
- U.S. locations
- 10
- States / cities
- Miami, Florida • Baltimore, Maryland • College Park, Maryland + 7 more
- Conditions
- Postoperative Cognitive Dysfunction, Delirium, Dementia, Neurotoxicity
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 65 Years to 95 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Hypertension
- Interventions
- Lumbar spine surgery, Neurologic/neuropsychometric examinations
- Procedure · Other
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 60 Years to 90 Years
- Enrollment
- 179 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2014
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Postoperative Cognitive Dysfunction, POCD
- Interventions
- Processed EEG
- Procedure
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 178 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Post-Operative Delirium, Postoperative Cognitive Dysfunction
- Interventions
- SctO2 < 60 %.
- Procedure
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Delirium
- Interventions
- Millipore biomarker assay plate
- Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 60 Years to 130 Years
- Enrollment
- 201 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Postoperative Delirium, PD, Postoperative Cognitive Dysfunction, POCD
- Interventions
- Precedex (Dexmedetomidine), Placebo
- Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Postoperative Cognitive Dysfunction
- Interventions
- Florbetapir F 18 (18F-AV-45), no intervention
- Drug · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2026
- U.S. locations
- 1
- States / cities
- San Francisco, California