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ClinicalTrials.gov public records Last synced May 22, 2026, 1:39 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–10 of 10 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pachyonychia Congenita Clear all
Completed Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Epidermolysis Bullosa Simplex, Pachyonychia Congenita
Interventions
Jojoba oil with broccoli sprout extract, Jojoba oil (placebo)
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced May 22, 2026, 1:39 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Epidermolytic Ichthyosis, Palmoplantar Keratoderma, Pachyonychia Congenita
Interventions
Erlotinib
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced May 22, 2026, 1:39 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Pachyonychia Congenita
Interventions
Not listed
Lead sponsor
Pachyonychia Congenita Project
Other
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2030
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced May 22, 2026, 1:39 AM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Pachyonychia Congenita
Interventions
TD101, Normal saline (placebo)
Drug
Lead sponsor
Pachyonychia Congenita Project
Other
Eligibility
10 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 18, 2008 · Synced May 22, 2026, 1:39 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Pachyonychia Congenita
Interventions
QTORIN 3.9% rapamycin anhydrous gel, Vehicle
Drug
Lead sponsor
Palvella Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
7
States / cities
Palo Alto, California • New Haven, Connecticut • Orange Park, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced May 22, 2026, 1:39 AM EDT
Completed Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Pachyonychia Congenita
Interventions
PTX-022, Placebo
Drug
Lead sponsor
Palvella Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
9
States / cities
Phoenix, Arizona • Palo Alto, California • New Haven, Connecticut + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced May 22, 2026, 1:39 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Darier Disease, Hailey-Hailey Disease, Hyperkeratosis, Epidermolytic, Ichthyosis, Ichthyosis, Lamellar, Ichthyosis, X-Linked, Keratoderma
Interventions
Not listed
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
Not listed
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2004
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced May 22, 2026, 1:39 AM EDT
Completed Phase 1 Interventional Results available
View directory record Official record
Conditions
Pachyonychia Congenita
Interventions
1% sirolimus cream (TD201 1%)
Drug
Lead sponsor
TransDerm, Inc.
Industry
Eligibility
16 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced May 22, 2026, 1:39 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Pachyonychia Congenita
Interventions
PTX-022
Drug
Lead sponsor
Palvella Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
4
States / cities
Phoenix, Arizona • Palo Alto, California • Fridley, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced May 22, 2026, 1:39 AM EDT
Recruiting Phase 3 Interventional
View directory record Official record
Conditions
Pachyonychia Congenita
Interventions
PTX-022
Drug
Lead sponsor
Palvella Therapeutics, Inc.
Industry
Eligibility
16 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Brighton, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced May 22, 2026, 1:39 AM EDT