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Showing 1–24 of 338 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pain, Neck Clear all
Recruiting Phase 3 Interventional

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

NCT06992427
View directory record Official record
Conditions
Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8, Stage II Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8, Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8, Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Interventions
Gabapentin, Placebo, Chemotheraphy, Radiation Therapy, Analgesic Agent, Biospecimen Collection, Survey Administration
Drug · Radiation · Procedure + 1 more
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
200
States / cities
Gilbert, Arizona • Peoria, Arizona • Phoenix, Arizona + 162 more
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 22, 2026, 6:41 PM EDT
Active, not recruiting No phase listed Observational

Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes

NCT05450679
View directory record Official record
Conditions
Cervical Facet Joint Pain, Chronic Pain, Neck Pain
Interventions
Cervical Radiofrequency Ablation (RFA)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimizing Mental Health in Orthopedic Care

NCT05194722
View directory record Official record
Conditions
Anxiety, Depression, Back Pain, Neck Pain
Interventions
Wysa mobile app
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 22, 2026, 6:41 PM EDT
Recruiting Not applicable Interventional

Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain

NCT07137715
View directory record Official record
Conditions
Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
Interventions
Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Osteopathic Manipulative Treatment on Neuromuscular Control of the Head-neck System

NCT02261259
View directory record Official record
Conditions
Neck Pain
Interventions
Osteopathic manipulative treatment
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
21 Years to 65 Years
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
3
States / cities
East Lansing, Michigan • Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

DilaCheck Cervical Dilation Measurement Trial

NCT03440723
View directory record Official record
Conditions
Cervical Dilation, Labor Pain, Labor Fast, Labor; Irregular
Interventions
DilaCheck, Cervical dilation examination
Device · Diagnostic Test
Lead sponsor
Elm Tree Medical Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Jul 22, 2026, 6:41 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

ATI Evidence-based Guide Investigating Clinical Services

NCT02285868
View directory record Official record
Conditions
Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee, Shoulder, Cervical/Thoracic, Foot/Ankle, Hip, Elbow, Neurological, Vestibular, Pelvic Floor, TMJ, Fibromyalgia, Headaches, Lymphedema
Interventions
Not listed
Lead sponsor
ATI Holdings, LLC
Industry
Eligibility
Not listed
Enrollment
4,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Lidocaine Patch for Neck Pain

NCT04378959
View directory record Official record
Conditions
Neck Pain, Neck Pain, Posterior
Interventions
Lidocaine patch, Placebo patch
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Jul 22, 2026, 6:41 PM EDT
Active, not recruiting Not applicable Interventional

Trident Multi-tined Cannula for Cervical MBRFA Compared to the Conventional Cannula

NCT05424198
View directory record Official record
Conditions
Cervical Pain, Cervical Facet Joint Pain
Interventions
Cervical Medial Branch Radiofrequency Ablation
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Farmington, Utah • Salt Lake City, Utah • South Jordan, Utah
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Clavicle Splint for Pain Reduction After Posterior Cervicothoracic Surgery

NCT01977690
View directory record Official record
Conditions
Posterior Cervical Surgery, Posterior Cervical Fusion, Posterior Cervical Laminectomy, Posterior Cervical Laminoplasty
Interventions
Clavicle Brace
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2017 · Synced Jul 22, 2026, 6:41 PM EDT
Active, not recruiting Not applicable Interventional

Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance

NCT06275074
View directory record Official record
Conditions
Neck Pain, Sleep Disturbance
Interventions
Dry Needling, Therapeutic Exercise
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Phase 1 Interventional

Patients With Neck Pain Likely to Benefit From Thoracic Spine Thrust Mobilization

NCT00504686
View directory record Official record
Conditions
Neck Pain
Interventions
manual therapy, exercise
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years to 60 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 2, 2009 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Phase 3 Interventional Results available

A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease

NCT01176240
View directory record Official record
Conditions
Orthostatic Hypotension, Parkinson's Disease
Interventions
Droxidopa, Placebo
Drug · Other
Lead sponsor
Chelsea Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
60
States / cities
Alabaster, Alabama • Gilbert, Arizona • Phoenix, Arizona + 53 more
Source: ClinicalTrials.gov public record
Updated May 19, 2014 · Synced Jul 22, 2026, 6:41 PM EDT
Suspended Not applicable Interventional

A Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain

NCT02972710
View directory record Official record
Conditions
Neck Pain
Interventions
Supine thoracic spine thrust manipulation, Seated thoracic spine thrust manipulation
Other
Lead sponsor
Northern Arizona University
Other
Eligibility
20 Years to 50 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Short-Term Effects of Combined Manual Therapy to the Cervical and Thoracic Spine

NCT01318720
View directory record Official record
Conditions
Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Masefield and Cavallaro Physical Therapy
Other
Eligibility
18 Years to 60 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Phase 2Phase 3 Interventional

Validation of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation: A Randomized Clinical Trial

NCT01571674
View directory record Official record
Conditions
Shoulder Pain
Interventions
Manipulation + Exercise Group, Exercise Group
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
9
States / cities
Aurora, Colorado • Boulder, Colorado • Concord, New Hampshire + 5 more
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Surgeons Can Avoid Lasting Pain Through Exercise Literacy

NCT05175443
View directory record Official record
Conditions
Neck Pain, Shoulder Pain
Interventions
Exercise
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
18 Years to 99 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Jul 22, 2026, 6:41 PM EDT
Withdrawn Phase 4 Interventional

Ketamine in Patients Undergoing Anterior Cervical Discectomy and Fusion

NCT02378740
View directory record Official record
Conditions
Anesthesia, Pain, Surgery
Interventions
Saline, Ketamine
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 14, 2016 · Synced Jul 22, 2026, 6:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neuroinflammation in Chronic Systemic Symptoms (CSS)

NCT04636723
View directory record Official record
Conditions
Cancer, Cancer Head Neck, Neuroinflammatory Response, Chronic Inflammation, Chronic Disease, Chronic Pain
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Palpatory Neuromodulation of the Trigeminal Nerve for Tenderness in the Posterior Neck Musculature

NCT04936659
View directory record Official record
Conditions
Neuromodulation, Neck Pain
Interventions
neuromodulation
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 65 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Jul 22, 2026, 6:41 PM EDT
Terminated Phase 3 Interventional

S9908: Glutamine in Treating Mucositis Caused by Radiation Therapy in Patients With Newly Diagnosed Cancer of the Mouth or Throat

NCT00006994
View directory record Official record
Conditions
Cancer-related Problem/Condition, Head and Neck Cancer, Pain
Interventions
glutamine, radiation therapy, l-glutamine placebo
Dietary Supplement · Radiation · Drug
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years to 90 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
106
States / cities
Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 68 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2015 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated

NCT03100539
View directory record Official record
Conditions
Neck Pain, Chronic Pain, Pain, Arthritis, Musculoskeletal Pain, Osteoarthritis
Interventions
Therapist treated massage, Care ally assisted massage
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Jul 22, 2026, 6:41 PM EDT
Completed No phase listed Observational

Investigation of Pain and Symptom Burden in Patients With Newly Diagnosed Head and Neck Cancer

NCT00655005
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
questionnaire administration, quality-of-life assessment
Other · Procedure
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 9, 2012 · Synced Jul 22, 2026, 6:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Tenaculum Pain Control Study

NCT01421641
View directory record Official record
Conditions
Cervical Pain, Pelvic Pain
Interventions
Intracervical Lidocaine Injection, Topical Lidocaine Gel
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Jul 22, 2026, 6:41 PM EDT