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Showing 1–24 of 650 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pain, Nerve Clear all
Withdrawn Not applicable Interventional

Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes

NCT03543033
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Corticosteroid injection
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
30 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Sep 12, 2026, 7:11 PM EDT
Not listed No phase listed Observational

SEXI: Sciatic Expression and Identification of Differential Proteins in Traumatized Versus Nontraumatized Nerves

NCT01710618
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Sep 12, 2026, 7:11 PM EDT
Terminated No phase listed Observational

A Pilot Study to Evaluate the Contribution of the Saphenous Nerve in Ankle Pain of Patients With Degenerative Joint Disease of the Ankle

NCT01716650
View directory record Official record
Conditions
Degenerative Joint Disease of the Ankle
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 7, 2019 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery

NCT04424810
View directory record Official record
Conditions
Anxiety, Carpal Tunnel Syndrome, Trigger Finger, Engagement, Patient, Pain
Interventions
High-quality, physician created video, Standard of care
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional Results available

Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia

NCT02898103
View directory record Official record
Conditions
Postoperative Pain
Interventions
Percutaneous peripheral nerve stimulation, Sham stimulation
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 12, 2026, 7:11 PM EDT
Terminated No phase listed Observational

Surgical Treatment of Chronic Neuropathic Pain

NCT04287075
View directory record Official record
Conditions
Chronic Neuropathic Pain
Interventions
Surgical Management of Neuroma
Procedure
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
Tampa, Florida • Indianapolis, Indiana • Salt Lake City, Utah + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for the Treatment of Back Pain Using Peripheral Nerve Stimulation (PNS)

NCT03179202
View directory record Official record
Conditions
Back Pain, Low Back Pain
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
8
States / cities
Peoria, Arizona • Walnut Creek, California • Washington D.C., District of Columbia + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Phase 4 Interventional Results available

Optimizing Local Anesthetic Concentration for Continuous Femoral Nerve Blocks

NCT00923598
View directory record Official record
Conditions
Total Knee Arthroplasty, Knee Pain
Interventions
0.1% and 0.4% perineural ropivicaine
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 1, 2019 · Synced Sep 12, 2026, 7:11 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

PatientSpot Formerly Known as ArthritisPower

NCT03840928
View directory record Official record
Conditions
Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
Interventions
Not listed
Lead sponsor
Global Healthy Living Foundation
Other
Eligibility
19 Years and older
Enrollment
40,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Upper Nyack, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Nerve Stimulation for Pain Control During First-trimester Abortion

NCT05320432
View directory record Official record
Conditions
Abortion in First Trimester, Pain
Interventions
Transcutaneous electrical nerve stimulation (TENS), Sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TENS for Testicular Pain (ICO): A Randomized Controlled Trial

NCT04866784
View directory record Official record
Conditions
Pain Management
Interventions
Transcutaneous Electrical Nerve Stimulation (TENS)
Device
Lead sponsor
Jennifer E. Lee
Other
Eligibility
18 Years to 99 Years · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional

Continuous Femoral Nerve Block Following Total Knee Replacement

NCT00135889
View directory record Official record
Conditions
Pain
Interventions
Femoral perineural infusion
Drug
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
La Jolla, California • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 7, 2009 · Synced Sep 12, 2026, 7:11 PM EDT
Recruiting Not applicable Interventional

Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain

NCT07166952
View directory record Official record
Conditions
Lower Back Pain
Interventions
SPRINT PNS System
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Continuous TAP Blocks: Relative Effects of a Basal Infusion vs. Repeated Bolus Doses

NCT02662023
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bolus, Basal
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries

NCT02313675
View directory record Official record
Conditions
Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
Interventions
Acetaminophen, Ketorolac Tromethamine, Saline
Drug
Lead sponsor
John Fowler
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Sep 12, 2026, 7:11 PM EDT
Not listed Not applicable Interventional

Peripheral Nerve Block Compared to Intra-articular Injection for TAA Post-operative Pain

NCT03674905
View directory record Official record
Conditions
Ankle Arthritis, Ankle Arthropathy
Interventions
Intra-articular injection, Peripheral nerve block
Procedure
Lead sponsor
Slocum Research & Education Foundation
Other
Eligibility
40 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 12, 2026, 7:11 PM EDT
Withdrawn Phase 4 Interventional

Adductor Canal Vs Adductor Canal Plus SPANK Block for Postoperative Pain in Knee Arthroplasty Surgery

NCT04290442
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Anesthesia, Conduction, Acute Pain
Interventions
adductor canal block, SPANK, Ropivacaine
Procedure · Drug
Lead sponsor
Bruce Ben-David
Other
Eligibility
19 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional Results available

Effects of TENS Therapy Following Arthroscopic Knee Surgery

NCT01528228
View directory record Official record
Conditions
Meniscus Tear
Interventions
TENS Treatment with functional or disabled unit
Device
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Sep 12, 2026, 7:11 PM EDT
Terminated Not applicable Interventional Results available

Peripheral Nerve Stimulation for Back

NCT04538430
View directory record Official record
Conditions
Back Pain
Interventions
SPRINT percutaneous peripheral nerve stimulator placed
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional Results available

Comparison of Pre-op and Post-op Pectoralis Nerve Block

NCT03653988
View directory record Official record
Conditions
Breast Cancer, Postoperative Pain, Anesthesia, Nerve Block
Interventions
PEC I/II blocks by anesthesiologist - pre-operative, PEC I/II blocks by surgeon - intra-operative
Procedure
Lead sponsor
Melinda Seering
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Sep 12, 2026, 7:11 PM EDT
Not listed Not applicable Interventional

Lumbar Plexus Catheter Versus Femoral Nerve Catheter for Postoperative Pain After Anterior Cruciate Ligament (ACL) Repair

NCT01068275
View directory record Official record
Conditions
Postoperative Pain
Interventions
lumbar plexus catheter, femoral nerve catheter, single-shot femoral block
Procedure
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 21 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 25, 2010 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lap-assisted vs. US-Guided Visualization of TAP Blocks

NCT04226300
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Laparoscopic, Ultrasound
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Up to 18 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2021 · Synced Sep 12, 2026, 7:11 PM EDT
Completed Phase 3 Interventional Results available

Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy

NCT00232141
View directory record Official record
Conditions
HIV Infections, Peripheral Neuropathy
Interventions
pregabalin, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
41
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 29 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Sep 12, 2026, 7:11 PM EDT
Recruiting Not applicable Interventional

Use of the Neurolyser XR for the Treatment of Low Back Pain Related to Sacroiliitis

NCT06053255
View directory record Official record
Conditions
Sacroiliitis
Interventions
High-intensity focused ultrasound for Sacroiliitis using the Neurolyser XR
Device
Lead sponsor
FUSMobile Inc.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 12, 2026, 7:11 PM EDT