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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Pain Response Clear all
Terminated No phase listed Observational Accepts healthy volunteers

Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain

NCT05386693
View directory record Official record
Conditions
Hernia, Inguinal, Chronic Postoperative Pain
Interventions
Ilioinguinal nerve block
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 1 Interventional

Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products

NCT04226690
View directory record Official record
Conditions
Pain
Interventions
Active CBD/THC Dose 1, Active CBD/THC Dose 2, matched placebo comparator
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 68 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 2 Interventional Results available

Genetic Effects on Dopamine Response to an Opiate

NCT01878006
View directory record Official record
Conditions
Polymorphism-Genetic, Pain, Addiction
Interventions
Morphine, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 55 Years · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 2 Interventional Results available

Study of MR-107A-02 in the Treatment of Post Surgical Dental Pain.

NCT05317312
View directory record Official record
Conditions
Acute Pain, Post Operative Pain, Pain
Interventions
MR-107A-02, Placebo
Drug
Lead sponsor
Mylan Specialty, LP
Industry
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Jul 23, 2026, 7:01 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Human Behaviors Related to the Expectation of Pain

NCT03739645
View directory record Official record
Conditions
Fear Pain
Interventions
Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
16 Years to 88 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 4 Interventional Results available

Pain Response Evaluation of a Combined Intervention to Cope Effectively

NCT04395001
View directory record Official record
Conditions
Chronic Pain
Interventions
duloxetine, Web-based Cognitive Behavioral Therapy (CBT), Nurse-delivered Motivational Interviewing
Drug · Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Terminated Not applicable Interventional Results available

Irritable Bowel Syndrome (IBS) Functional Magnetic Resonance Imaging (fMRI) With Desipramine

NCT00880594
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Desipramine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Interventional Results available

Predicting Pain Response to Transcranial Direct Current Stimulation for Phantom Limb Pain in Limb Amputees

NCT02627495
View directory record Official record
Conditions
Phantom Limb Pain
Interventions
transcranial Direct Current Stimulation (tDCS): (Soterix ©)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 2 Interventional Results available

Randomized Trial Assessing Quinagolide Vaginal Ring for Endometriosis-related Pain

NCT03692403
View directory record Official record
Conditions
Endometriosis-related Pain
Interventions
Quinagolide 360 µg, Quinagolide 720 µg, Quinagolide 1080 µg, Placebo
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
43
States / cities
Mesa, Arizona • Little Rock, Arkansas • San Diego, California + 36 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2023 · Synced Jul 23, 2026, 7:01 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Music Based Intervention (MBI) on Pain Response and Neurodevelopment in Preterm Infants

NCT04286269
View directory record Official record
Conditions
Preterm Birth, Pain
Interventions
Music Based Intervention, Sham Treatment
Other
Lead sponsor
University of Minnesota
Other
Eligibility
28 Weeks to 32 Weeks
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

The Innate Central Nervous System Immune Response to an Experimental Immune Challenge in People With Fibromyalgia

NCT04263454
View directory record Official record
Conditions
Fibromyalgia
Interventions
Endotoxin, Escherichia Coli, Magnetic Resonance Spectroscopy
Drug · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional

Neuroimaging and Biomarkers in Chronic Visceral Pain

NCT01602575
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Mindfulness based Stress Reduction Training (MBSR)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 13, 2018 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 1 Interventional Results available

Epidural Neostigmine for Labor Pain

NCT00779467
View directory record Official record
Conditions
Labor Pain
Interventions
Neostigmine, Bupivacaine, fentanyl
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nutramax Joint Health Formulation Biochemical Response Study

NCT02614274
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Nutraceutical joint health formulation
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
40 Years to 64 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 4, 2018 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effera Dose Response: Women's Health

NCT07524270
View directory record Official record
Conditions
Womens Health, Menstrual Symptoms
Interventions
Effera® (human equivalent lactoferrin), Placebo
Dietary Supplement · Other
Lead sponsor
Helaina Inc.
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Altered Immune Response to Exercise in Patients With Fibromyalgia Before and After a Mind-body Intervention

NCT03441997
View directory record Official record
Conditions
Fibromyalgia
Interventions
Mind-body exercise, Light mobility exercises
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 2 Interventional

IMX-150 Cream for Diabetic Neuropathy

NCT00641953
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
IMX-150, Placebo
Drug
Lead sponsor
Procris Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
7
States / cities
Brooksville, Florida • Jupiter, Florida • Miami, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2008 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting Not applicable Interventional

Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response

NCT05188183
View directory record Official record
Conditions
Phantom Limb Pain
Interventions
M1 anodal home-based tDCS, Somatosensory Training, Usual Care
Device · Behavioral · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational

Myofascial Pain and Central Sensitization

NCT04929171
View directory record Official record
Conditions
Myofascial Pain, Physical Therapy
Interventions
Physical Therapy
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Pain After Buffered Vs Non Buffered Articaine

NCT06538233
View directory record Official record
Conditions
Pain
Interventions
Buffered articaine, Non buffered articaine
Drug
Lead sponsor
Cleveland Dental Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 4, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational

Spinal Cord Stimulation Research Study

NCT00737581
View directory record Official record
Conditions
Chronic Low Back and Leg Pain
Interventions
Not listed
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
Edina, Minnesota • Garland, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Response to Pain Control in People With Chronic Pain

NCT01878019
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 8, 2019 · Synced Jul 23, 2026, 7:01 AM EDT
Terminated Not applicable Interventional Results available

A Phase I/II Dose Escalation Study Using Extracranial Stereotactic Radiosurgery to Control Pain

NCT00802659
View directory record Official record
Conditions
Metastases
Interventions
Stereotactic radiotherapy
Radiation
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Jul 23, 2026, 7:01 AM EDT