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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pancreas Necrosis Clear all
Completed No phase listed Observational

A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes

NCT06227871
View directory record Official record
Conditions
Pancreatic Trauma, Pancreatic Duct Injury, Pancreas Necrosis, Pancreas Cyst, Pancreas; Fistula, Pancreas Abscess, Intra-Abdominal Abscess, Anastomotic Leak, Pancreas Injury
Interventions
Exploratory laparotomy
Procedure
Lead sponsor
Kern Medical Center
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2024 · Synced Jul 21, 2026, 1:26 PM EDT
Recruiting Not applicable Interventional

Necrosectomy With Cryotechnology for Accelerated Removal

NCT06553651
View directory record Official record
Conditions
Pancreatic Necrosis, Acute Pancreatitis, Acute Pancreatic Necrosis, Necrosis, Necrosis Pancreas, Walled-Off Pancreatic Necrosis
Interventions
Cryotechnology Necrosectomy Procedure
Device
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Early Phase 1 Interventional

Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer

NCT00436410
View directory record Official record
Conditions
Adrenocortical Carcinoma, Breast Cancer, Colorectal Cancer, Gastrointestinal Cancer, Kidney Cancer, Liver Cancer, Melanoma (Skin), Ovarian Cancer, Pancreatic Cancer, Sarcoma
Interventions
colloidal gold-bound tumor necrosis factor, electron microscopy, pharmacological study, conventional surgery
Biological · Other · Procedure
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 1, 2012 · Synced Jul 21, 2026, 1:26 PM EDT
Recruiting No phase listed Observational

Registry of Patients Undergoing Endoscopic Management of Pancreatic Fluid Collections

NCT06179459
View directory record Official record
Conditions
Acute Pancreatitis, Pancreatic Pseudocyst, Pancreatic Necrosis
Interventions
Endoscopic management of pancreatic fluid collections
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Minimally Invasive Surgery vs. Endoscopy Randomized (MISER) Trial for Necrotizing Pancreatitis

NCT02084537
View directory record Official record
Conditions
Necrosis of Pancreas, Infected Pancreatic Necrosis
Interventions
Endoscopic treatment, Minimally invasive surgical necrosectomy
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2019 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Early Phase 1 Interventional Results available

Pentoxifylline Treatment of Acute Pancreatitis

NCT01292005
View directory record Official record
Conditions
Acute Pancreatitis
Interventions
Pentoxifylline, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Jul 21, 2026, 1:26 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Imaging Modalities for Pancreatic Collections

NCT03556501
View directory record Official record
Conditions
Pancreas Necrosis
Interventions
Endoscopy
Diagnostic Test
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2023 · Synced Jul 21, 2026, 1:26 PM EDT
Recruiting No phase listed Observational

DEciphering CIrculating SIgnatures Of Infected Pancreatic Necrosis

NCT06899087
View directory record Official record
Conditions
Acute Pancreatitis
Interventions
not interventional
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Not applicable Interventional Results available

EndoRotor DEN (Direct Endoscopic Necrosectomy)Trial

NCT03694210
View directory record Official record
Conditions
Acute Pancreatic Necrosis, Acute Pancreatitis, Necrotizing Pancreatitis
Interventions
EndoRotor Therapy
Device
Lead sponsor
Interscope, Inc.
Industry
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
7
States / cities
Little Rock, Arkansas • Palo Alto, California • San Francisco, California + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Jul 21, 2026, 1:26 PM EDT
Completed No phase listed Observational

Rad Predictors for WON

NCT03801070
View directory record Official record
Conditions
Walled Off Pancreatic Necrosis (WON)
Interventions
endoscopic drainage of walled off pancreatic necrosis
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
19 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Jul 21, 2026, 1:26 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

PatientSpot Formerly Known as ArthritisPower

NCT03840928
View directory record Official record
Conditions
Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
Interventions
Not listed
Lead sponsor
Global Healthy Living Foundation
Other
Eligibility
19 Years and older
Enrollment
40,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Upper Nyack, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Jul 21, 2026, 1:26 PM EDT
Terminated Phase 1 Interventional

One Time Injection of Bacteria to Treat Solid Tumors That Have Not Responded to Standard Therapy

NCT00358397
View directory record Official record
Conditions
Tumors
Interventions
Clostridium novyi-NT spores
Drug
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2016 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Comparison of FCSEMS and Plastic Stents

NCT02685865
View directory record Official record
Conditions
Infected Pancreatic Necrosis, Acute Pancreatic Fluid Collection, Pancreatic and Peripancreatic Necrosis, Pancreatic Collection, Symptomatic Pancreatic Necrosis
Interventions
FCSEM Stent, Plastic Stent
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2019 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Videoendoscopic Drainage of Infected Pancreatic Collections

NCT00061269
View directory record Official record
Conditions
Pancreatitis, Acute Necrotizing
Interventions
Videoscopic-Assisted Retroperitoneal Debridement (VARD)
Procedure
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
5
States / cities
Portland, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jul 21, 2026, 1:26 PM EDT
Enrolling by invitation Not applicable Interventional

Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of Necrosis

NCT04814693
View directory record Official record
Conditions
Acute Pancreatitis, Necrosis; Pancreas, Acute (Infectious)
Interventions
EndoRotor® System (Interscope, Inc., Northbridge, MA USA),, Conventional endoscopic devices (according to standards of care)
Device · Procedure
Lead sponsor
Erasmus Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Birmingham, Alabama • San Francisco, California • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Endoscopic Necrosectomy Versus Step-up Endoscopic Intervention

NCT04113499
View directory record Official record
Conditions
Pancreatic Necrosis, Necrosis Pancreas
Interventions
Direct Endoscopic Intervention, Step-up Endoscopic Intervention
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Not applicable Interventional Results available

AXIOS Lumen Apposing Metal Stent for Walled Off Necrosis Drainage IDE Study

NCT03525808
View directory record Official record
Conditions
Walled Off Pancreatic Necrosis
Interventions
AXIOS
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
5
States / cities
Aurora, Colorado • Atlanta, Georgia • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2021 · Synced Jul 21, 2026, 1:26 PM EDT
Recruiting Not applicable Interventional

Strategic Timing of Endoscopic Interventions in Infected Necrotizing Pancreatitis

NCT07406698
View directory record Official record
Conditions
Pancreatitis, Acute Necrotizing
Interventions
EUS-guided transluminal drainage of necrotic collection
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 21, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Pancreatic Duct Stent for Acute Necrotizing Pancreatitis

NCT03115918
View directory record Official record
Conditions
Necrotizing Pancreatitis, Walled Off Necrosis
Interventions
Pancreatic Duct Stent Placement, No Pancreatic Duct Stent Placement
Device · Other
Lead sponsor
AdventHealth
Other
Eligibility
19 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Jul 21, 2026, 1:26 PM EDT
Terminated Not applicable Interventional Results available

Study of a Lumen- Apposing, Covered, Self-Expanding Metal Stent (Axios™) Versus Multiple Double Pigtail Stents

NCT02673541
View directory record Official record
Conditions
Pancreatic Necrosis
Interventions
AXIOS™ stent, Double Pigtail Stents
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 5, 2020 · Synced Jul 21, 2026, 1:26 PM EDT